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P2B P-type ATPases: Ca2+-ATPases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

847
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Target Id 847
Nomenclature SPCA1
Previous and unofficial names ATPase 2C1 | ATP-dependent Ca2+ pump PMR1 | ATP2C1A | BCPM | PMR1 | benign chronic pemphigus (Hailey-Hailey disease) | secretory pathway Ca2+/Mn2+ ATPase 1 | ATPase, Ca++ transporting, type 2C, member 1 | ATPase, Ca++-sequestering | calcium-transporting ATPase 2C1 | SPCA | ATPase, Ca� transporting, type 2C, member 1 | ATPase
Genes ATP2C1 (Hs), Atp2c1 (Mm), Atp2c1 (Rn)
Ensembl ID ENSG00000017260 (Hs), ENSMUSG00000032570 (Mm), ENSRNOG00000013305 (Rn)
UniProtKB AC P98194 (Hs), Q80XR2 (Mm), Q64566 (Rn)
EC number
3.6.3.8

SPCA2 Show summary »

How to cite this family page

Database page citation:

P2B P-type ATPases: Ca2+-ATPases. Accessed on 16/08/2026. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1045.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Gibb AJ, Kelly E, Mathie AA, Peach CJ, Veale EL, Armstrong JF, Faccenda E, Harding SD, Southan C, Davies JA et al. (2025) The Concise Guide to PHARMACOLOGY 2025/26: Transporters. Br J Pharmacol. 182: S404-S496.