target,target_id,target_uniprot,target_species,ligand,ligand_id,ligand_species,ligand_pubchem_cid,smiles,inchi,inchikey,type,action,action_comment,endogenous,primary_target,concentration_range,affinity_parameter,affinity_high,affinity_median,affinity_low,original_affinity_units,original_affinity_low_nm,original_affinity_median_nm,original_affinity_high_nm,original_affinity_relation,assay_description,receptor_site,ligand_context,pubmed_id bone morphogenetic protein receptor type IA,1786,P36894,Human,compound 13d [PMID: 23639540],8120,,60182389,O1CCN(CC1)c1ccc(cc1)c1cnc2n(c1)ncc2c1ccnc2c1cccc2,"InChI=1S/C25H21N5O/c1-2-4-24-22(3-1)21(9-10-26-24)23-16-28-30-17-19(15-27-25(23)30)18-5-7-20(8-6-18)29-11-13-31-14-12-29/h1-10,15-17H,11-14H2",SZVLDZCYMADNPG-UHFFFAOYSA-N,Inhibitor,Inhibition,,,yes,,pIC50,,8.3,,IC50,,5.0,,<,,,,23639540, bone morphogenetic protein receptor type IA,1786,P36894,Human,ML347,8121,,44577753,COc1ccc(cc1)c1cnc2n(c1)ncc2c1cccc2c1cccn2,"InChI=1S/C22H16N4O/c1-27-17-9-7-15(8-10-17)16-12-24-22-20(13-25-26(22)14-16)18-4-2-6-21-19(18)5-3-11-23-21/h2-14H,1H3",FVRYPYDPKSZGNS-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,4.97,,IC50,,10800.0,,=,,,,23639540, bone morphogenetic protein receptor type IA,1786,P36894,Human,compound 13r [PMID: 23639540],8144,,60182364,CN1CCN(CC1)c1ccc(cc1)c1cnc2n(c1)ncc2c1ccnc2c1cccc2,"InChI=1S/C26H24N6/c1-30-12-14-31(15-13-30)21-8-6-19(7-9-21)20-16-28-26-24(17-29-32(26)18-20)22-10-11-27-25-5-3-2-4-23(22)25/h2-11,16-18H,12-15H2,1H3",XBGWAKUQSRNWMA-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,8.3,,IC50,,5.0,,<,,,,23639540, bone morphogenetic protein receptor type IA,1786,P36894,Human,compound 13a [PMID: 23639540],8155,,60182393,O1CCN(CC1)c1ccc(cc1)c1cnc2n(c1)ncc2c1cn[nH]c1,"InChI=1S/C19H18N6O/c1-3-17(24-5-7-26-8-6-24)4-2-14(1)16-9-20-19-18(12-23-25(19)13-16)15-10-21-22-11-15/h1-4,9-13H,5-8H2,(H,21,22)",WCDLCPLAAKUJNY-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,7.98,,IC50,,10.4,,=,,,,23639540, bone morphogenetic protein receptor type IA,1786,P36894,Human,LDN-214117,8481,,91754554,COc1cc(cc(c1OC)OC)c1cc(cnc1C)c1ccc(cc1)N1CCNCC1,"InChI=1S/C25H29N3O3/c1-17-22(19-14-23(29-2)25(31-4)24(15-19)30-3)13-20(16-27-17)18-5-7-21(8-6-18)28-11-9-26-10-12-28/h5-8,13-16,26H,9-12H2,1-4H3",BHUXVRVMMYAXKN-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,5.93,,IC50,,1171.0,,=,,,,25101911, bone morphogenetic protein receptor type IA,1786,P36894,Human,zilurgisertib,11888,,138628908,Nc1ncc(cc1C(=O)NC12CCC(CC1)(CC2)O)c1ccc(cc1)[C@]12CN(C[C@H]1C2)C1CCOCC1,"InChI=1S/C30H38N4O3/c31-26-25(27(35)33-28-7-10-29(36,11-8-28)12-9-28)15-21(17-32-26)20-1-3-22(4-2-20)30-16-23(30)18-34(19-30)24-5-13-37-14-6-24/h1-4,15,17,23-24,36H,5-14,16,18-19H2,(H2,31,32)(H,33,35)/t23-,28?,29?,30+/m1/s1",KPRPFTOLWQQUAV-OCVAFRRMSA-N,Inhibitor,Inhibition,,,,,pIC50,,6.04,,IC50,,914.0,,=,,,,, bone morphogenetic protein receptor type IA,1786,P36894,Human,K02288,13266,,46173038,COC1=CC(=CC(=C1OC)OC)C2=C(N=CC(=C2)C3=CC(=CC=C3)O)N,"InChI=1S/C20H20N2O4/c1-24-17-9-13(10-18(25-2)19(17)26-3)16-8-14(11-22-20(16)21)12-5-4-6-15(23)7-12/h4-11,23H,1-3H3,(H2,21,22)",CJLMANFTWLNAKC-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,7.46,,IC50,,34.3,,=,,,,34780900,