target,target_id,target_uniprot,target_species,ligand,ligand_id,ligand_species,ligand_pubchem_cid,smiles,inchi,inchikey,type,action,action_comment,endogenous,primary_target,concentration_range,affinity_parameter,affinity_high,affinity_median,affinity_low,original_affinity_units,original_affinity_low_nm,original_affinity_median_nm,original_affinity_high_nm,original_affinity_relation,assay_description,receptor_site,ligand_context,pubmed_id activin A receptor type 1B,1787,P36896,Human,galunisertib,7797,,10090485,Cc1cccc(n1)c1nn2c(c1c1ccnc3c1cc(cc3)C(=O)N)CCC2,"InChI=1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28)",IVRXNBXKWIJUQB-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,7.11,,IC50,,78.0,,=,Value determined usinfg the DiscoverX KINOMEscan platform.,,,29467918, activin A receptor type 1B,1787,P36896,Human,vactosertib,8107,,54766013,Cc1cccc(n1)c1[nH]c(nc1c1ccc2n(c1)ncn2)CNc1ccccc1F,"InChI=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)",FJCDSQATIJKQKA-UHFFFAOYSA-N,Inhibitor,Inhibition,,,yes,,pIC50,,7.89,,IC50,,13.0,,=,Measured using Reaction Biology Corporation's HotSpot kinase assay,,,24786585, activin A receptor type 1B,1787,P36896,Human,compound 13d [PMID: 23639540],8120,,60182389,O1CCN(CC1)c1ccc(cc1)c1cnc2n(c1)ncc2c1ccnc2c1cccc2,"InChI=1S/C25H21N5O/c1-2-4-24-22(3-1)21(9-10-26-24)23-16-28-30-17-19(15-27-25(23)30)18-5-7-20(8-6-18)29-11-13-31-14-12-29/h1-10,15-17H,11-14H2",SZVLDZCYMADNPG-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,6.49,,IC50,,326.0,,=,,,,23639540, activin A receptor type 1B,1787,P36896,Human,compound 13r [PMID: 23639540],8144,,60182364,CN1CCN(CC1)c1ccc(cc1)c1cnc2n(c1)ncc2c1ccnc2c1cccc2,"InChI=1S/C26H24N6/c1-30-12-14-31(15-13-30)21-8-6-19(7-9-21)20-16-28-26-24(17-29-32(26)18-20)22-10-11-27-25-5-3-2-4-23(22)25/h2-11,16-18H,12-15H2,1H3",XBGWAKUQSRNWMA-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,6.74,,IC50,,183.0,,=,,,,23639540, activin A receptor type 1B,1787,P36896,Human,BMS-986260,10662,,122510453,OCCn1cnc(c1c1ccc2n(n1)c(C#N)cn2)c1ccc(c(c1)Cl)F,"InChI=1S/C18H12ClFN6O/c19-13-7-11(1-2-14(13)20)17-18(25(5-6-27)10-23-17)15-3-4-16-22-9-12(8-21)26(16)24-15/h1-4,7,9-10,27H,5-6H2",VZZBCNXVZFAIQX-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,7.48,,IC50,,33.3,,=,,,,32071685,