target,target_id,target_uniprot,target_species,ligand,ligand_id,ligand_species,ligand_pubchem_cid,smiles,inchi,inchikey,type,action,action_comment,endogenous,primary_target,concentration_range,affinity_parameter,affinity_high,affinity_median,affinity_low,original_affinity_units,original_affinity_low_nm,original_affinity_median_nm,original_affinity_high_nm,original_affinity_relation,assay_description,receptor_site,ligand_context,pubmed_id dual specificity tyrosine phosphorylation regulated kinase 2,2011,Q92630,Human,compound 3b [PMID: 23454515],8127,,136234578,NCCOCCOCCOCCOc1ccc(cc1)NC1=N/C(=C\c2ccc3c(c2)OCO3)/C(=O)N1,"InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30)/b21-15-",ZBYBDKHFLSHGBP-QNGOZBTKSA-N,Inhibitor,Inhibition,,,,,pIC50,,6.89,,IC50,,130.0,,=,,,,23454515, dual specificity tyrosine phosphorylation regulated kinase 2,2011,Q92630,Human,leucettine L41,8167,,135398522,O=C1NC(=N/C/1=C\c1ccc2c(c1)OCO2)Nc1ccccc1,"InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21)/b13-8-",PGPHHJBZEGSUNE-JYRVWZFOSA-N,Inhibitor,Inhibition,,,yes,,pIC50,,9.46,,IC50,,0.35,,=,,,,21615147, dual specificity tyrosine phosphorylation regulated kinase 2,2011,Q92630,Human,compound 5b [PMID: 24900464],8171,,136254272,N#Cc1cnn2c1nc(cc2NC1CC1)c1c[nH]c2c1cc(cc2)NC(=O)C,"InChI=1S/C20H17N7O/c1-11(28)24-14-4-5-17-15(6-14)16(10-22-17)18-7-19(25-13-2-3-13)27-20(26-18)12(8-21)9-23-27/h4-7,9-10,13,22,25H,2-3H2,1H3,(H,24,28)",UZZGMJZTCZOSGC-UHFFFAOYSA-N,Inhibitor,Inhibition,,,,,pIC50,,7.22,,IC50,,60.0,,=,,,,24900464,