target,target_id,target_uniprot,target_species,ligand,ligand_id,ligand_species,ligand_pubchem_cid,smiles,inchi,inchikey,type,action,action_comment,endogenous,primary_target,concentration_range,affinity_parameter,affinity_high,affinity_median,affinity_low,original_affinity_units,original_affinity_low_nm,original_affinity_median_nm,original_affinity_high_nm,original_affinity_relation,assay_description,receptor_site,ligand_context,pubmed_id Fc fragment of IgG receptor and transporter,2985,P55899,Human,efgartigimod alfa,9777,,,,,,Antibody,Binding,,,,,,,,,,,,,=,,,,, Fc fragment of IgG receptor and transporter,2985,P55899,Human,rozanolixizumab,9801,,,,,,Antibody,Binding,,,,,pKd,8.7,,8.22,Kd,6.0,,2.0,~,"In a cell- based in vitro assay using neutral buffer. Note this affinity range is for the 01519.g57 Fab or PEGylated Fab fragment, not the intact IgG4P antibody.",,,, Fc fragment of IgG receptor and transporter,2985,P55899,Human,DX-2507,9959,,,,,,Antibody,Antagonist,,,yes,,pKd,,8.74,,Kd,,1.8,,=,Binding affinity at acidic pH (6.0).,,,25954273, Fc fragment of IgG receptor and transporter,2985,P55899,Human,ziltivekimab,11552,,,,,,Antibody,Binding,,,,,pKd,,6.65,,Kd,,226.0,,=,,,,21723291, Fc fragment of IgG receptor and transporter,2985,,Monkey,ziltivekimab,11552,,,,,,Antibody,Binding,,,,,pKd,,6.44,,Kd,,365.0,,=,Binding affinity for cynomolgus monkey FcRn,,,21723291,