{
    "comments": "Human, rat and mouse glucagon sequences are identical. The compound used as a drug is recombinantly produced.",
    "bioactivityComments": "",
    "clinicalUse": "Used to treat low blood sugar levels in hypoglycemic patients. As glucagon relaxes the smooth muscles of the gastrointestinal tract it is sometimes used in gastric imaging procedures.",
    "mechanismOfAction": "Glucagon acts in the liver resulting in the conversion of glycogen stores to glucose. The first step of the process is glucagon-induced activation of the glucagon receptor, triggering a signalling cascade which culminates in the activation of phosphorylase A, the enzyme responsible for the release of glucose-1-phosphate from glycogen polymers.",
    "absorptionAndDistribution": "",
    "metabolism": "",
    "elimination": "",
    "populationPharmacokinetics": "",
    "organFunctionImpairment": "",
    "immuno": "",
    "gtmp": ""
}