[
    {
        "interactionId": 77126,
        "targetId": 246,
        "targetName": "ghrelin receptor",
        "ligandAsTargetId": 0,
        "targetSpecies": "Human",
        "primaryTarget": false,
        "targetBindingSite": "",
        "ligandId": 5867,
        "ligandName": "ibutamoren",
        "ligandContext": "",
        "endogenous": false,
        "type": "Agonist",
        "action": "Full agonist",
        "actionComment": "",
        "selectivity": "Not Determined",
        "concentrationRange": "",
        "affinity": "9.3",
        "affinityParameter": "pKi",
        "originalAffinity": "4.6x10<sup>-10</sup>",
        "originalAffinityType": "Ki",
        "originalAffinityRelation": "=",
        "assayDescription": "",
        "assayConditions": "",
        "useDependent": false,
        "voltageDependent": false,
        "voltage": "",
        "physiologicalVoltage": false,
        "conciseView": false,
        "refs": [
            {
                "referenceId": 19864,
                "pmid": 10427162,
                "type": "Journal",
                "title": "Eur J Endocrinol",
                "year": 1999,
                "volume": "141",
                "issue": "2",
                "pages": "180-9",
                "articleTitle": "Pharmacological characterisation of a new oral GH secretagogue, NN703.",
                "authors": "Hansen BS, Raun K, Nielsen KK, Johansen PB, Hansen TK, Peschke B, Lau J, Andersen PH, Ankersen M",
                "pubStatus": ""
            }
        ]
    },
    {
        "interactionId": 77127,
        "targetId": 246,
        "targetName": "ghrelin receptor",
        "ligandAsTargetId": 0,
        "targetSpecies": "Human",
        "primaryTarget": false,
        "targetBindingSite": "",
        "ligandId": 5867,
        "ligandName": "ibutamoren",
        "ligandContext": "",
        "endogenous": false,
        "type": "Agonist",
        "action": "Full agonist",
        "actionComment": "Calcium release, IP<sub>3</sub> accumulation.",
        "selectivity": "Not Determined",
        "concentrationRange": "",
        "affinity": "8.6 - 9.7",
        "affinityParameter": "pEC50",
        "originalAffinity": "2.4x10<sup>-9</sup> - 1.9x10<sup>-10</sup>",
        "originalAffinityType": "EC50",
        "originalAffinityRelation": "=",
        "assayDescription": "",
        "assayConditions": "",
        "useDependent": false,
        "voltageDependent": false,
        "voltage": "",
        "physiologicalVoltage": false,
        "conciseView": false,
        "refs": [
            {
                "referenceId": 19860,
                "pmid": 15905359,
                "type": "Journal",
                "title": "Mol Endocrinol",
                "year": 2005,
                "volume": "19",
                "issue": "9",
                "pages": "2400-11",
                "articleTitle": "Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling.",
                "authors": "Holst B, Brandt E, Bach A, Heding A, Schwartz TW",
                "pubStatus": ""
            },
            {
                "referenceId": 19864,
                "pmid": 10427162,
                "type": "Journal",
                "title": "Eur J Endocrinol",
                "year": 1999,
                "volume": "141",
                "issue": "2",
                "pages": "180-9",
                "articleTitle": "Pharmacological characterisation of a new oral GH secretagogue, NN703.",
                "authors": "Hansen BS, Raun K, Nielsen KK, Johansen PB, Hansen TK, Peschke B, Lau J, Andersen PH, Ankersen M",
                "pubStatus": ""
            }
        ]
    }
]