[
    {
        "interactionId": 78539,
        "targetId": 2579,
        "targetName": "integrin &alpha;IIb&beta;3",
        "ligandAsTargetId": 0,
        "targetSpecies": "Human",
        "primaryTarget": true,
        "targetBindingSite": "",
        "ligandId": 6585,
        "ligandName": "eptifibatide",
        "ligandContext": "",
        "endogenous": false,
        "type": "Inhibitor",
        "action": "Inhibition",
        "actionComment": "",
        "selectivity": "Not Determined",
        "concentrationRange": "",
        "affinity": "6.2 - 6.8",
        "affinityParameter": "pIC50",
        "originalAffinity": "5.7x10<sup>-7</sup> - 1.4x10<sup>-7</sup>",
        "originalAffinityType": "IC50",
        "originalAffinityRelation": "=",
        "assayDescription": "inhibition of human platelet aggregation. The IC50 varies according to the anti-coagulant used during blood collection.",
        "assayConditions": "",
        "useDependent": false,
        "voltageDependent": false,
        "voltage": "",
        "physiologicalVoltage": false,
        "conciseView": true,
        "refs": [
            {
                "referenceId": 30053,
                "pmid": 10999999,
                "type": "Journal",
                "title": "J Med Chem",
                "year": 2000,
                "volume": "43",
                "issue": "19",
                "pages": "3453-73",
                "articleTitle": "Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents.",
                "authors": "Scarborough RM, Gretler DD",
                "pubStatus": ""
            }
        ]
    }
]