{
    "comments": "Macimorelin is a ghrelin peptidomimetic <Reference id=33980/>. It is a growth hormone (GH) secretagogue. The approved drug is the acetate salt (PubChem <a href=\"https://pubchem.ncbi.nlm.nih.gov/compound/71526737\" target=\"_blank\">CID 71526737</a>)- we show the parent molecule in this entry.",
    "bioactivityComments": "In human subjects macimorelin stimulates rapid GH release after <i>i.v.</i> injection.<Reference id=33980/>. The acetate salt is orally active.",
    "clinicalUse": "Macimorelin is FDA approved as a GH secretagogue for use in the diagnosis of adult GH deficiency <Reference id=33981/><Reference id=33982/>.",
    "mechanismOfAction": "Macimorelin binds to the ptiuitary ghrelin receptor and stimulates GH release.",
    "absorptionAndDistribution": "",
    "metabolism": "",
    "elimination": "",
    "populationPharmacokinetics": "",
    "organFunctionImpairment": "",
    "immuno": "",
    "gtmp": ""
}