[
{
"ligandId": 2779,
"name": "1,25-dihydroxyvitamin D3",
"type": "Metabolite",
"abbreviation": "",
"inn": "calcitriol",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1013,
"name": "17β-estradiol",
"type": "Metabolite",
"abbreviation": "E2",
"inn": "estradiol",
"approvalSource": "FDA (1954, prior history unavailable)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7655
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4108,
"name": "5α-pregnan-3α-ol-20-one",
"type": "Metabolite",
"abbreviation": "",
"inn": "brexanolone",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4784,
"name": "5-aminolevulinic acid",
"type": "Metabolite",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1999)m EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4789,
"name": "5-fluorouracil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluorouracil",
"approvalSource": "FDA (1962)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6799,
4801
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6574,
"name": "6-aminocaproic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aminocaproic acid",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11152,
"name": "abacavir",
"type": "Synthetic organic",
"abbreviation": "ABC",
"inn": "abacavir",
"approvalSource": "FDA (1998), EMA (1999)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8299,
"name": "abaloparatide",
"type": "Peptide",
"abbreviation": "",
"inn": "abaloparatide",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 1188,
"name": "abarelix",
"type": "Peptide",
"abbreviation": "",
"inn": "abarelix",
"approvalSource": "FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6891,
"name": "abatacept",
"type": "Peptide",
"abbreviation": "",
"inn": "abatacept",
"approvalSource": "FDA (2005), EMA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6584,
"name": "abciximab",
"type": "Antibody",
"abbreviation": "",
"inn": "abciximab",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7382,
"name": "abemaciclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "abemaciclib",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9288,
"name": "abiraterone acetate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "EMA & FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6745
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9991,
"name": "abrocitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "abrocitinib",
"approvalSource": "UK, Japan & EMA (2021), FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8912,
"name": "acalabrutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acalabrutinib",
"approvalSource": "FDA (2017), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7106,
"name": "acamprosate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acamprosate",
"approvalSource": "FDA (2004)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6791,
"name": "acarbose",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acarbose",
"approvalSource": "FDA (2007), UK (2009), Germany, France, Hungary, Poland, Portugal (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7107,
"name": "acebutolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acebutolol",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14102,
"name": "aceclidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aceclidine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9015,
"name": "acenocoumarol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acenocoumarol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6792,
"name": "acetazolamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acetazolamide",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6793,
"name": "acetohexamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acetohexamide",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10945,
"name": "acetylcysteine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acetylcysteine",
"approvalSource": "FDA (1963), UK (1992)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6794,
"name": "acetyldigitoxin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acetyldigitoxin",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4829,
"name": "aciclovir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aciclovir",
"approvalSource": "FDA (1982, prior history not available)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1596,
"name": "acipimox",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acipimox",
"approvalSource": "UK (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7598,
"name": "acitretin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acitretin",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7449,
"name": "aclidinium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aclidinium bromide",
"approvalSource": "FDA and EMA (2012)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4343,
"name": "acoltremon",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acoltremon",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13628,
"name": "acoramidis",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "acoramidis",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3633,
"name": "ACTH",
"type": "Peptide",
"abbreviation": "",
"inn": "corticotropin",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 10888,
"name": "adagrasib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "adagrasib",
"approvalSource": "FDA (2022), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4860,
"name": "adalimumab",
"type": "Antibody",
"abbreviation": "",
"inn": "adalimumab",
"approvalSource": "FDA (2002), EMA (2003)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5429,
"name": "adapalene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "adapalene",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13085,
"name": "adebrelimab",
"type": "Antibody",
"abbreviation": "",
"inn": "adebrelimab",
"approvalSource": "China NMPA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2844,
"name": "adenosine",
"type": "Metabolite",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 479,
"name": "(-)-adrenaline",
"type": "Metabolite",
"abbreviation": "",
"inn": "epinephrine,racepinefrine",
"approvalSource": "FDA (no history prior to 1951)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8325,
"name": "aducanumab",
"type": "Antibody",
"abbreviation": "",
"inn": "aducanumab",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1324,
"name": "afamelanotide",
"type": "Peptide",
"abbreviation": "",
"inn": "afamelanotide",
"approvalSource": "EMA (2014), FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 5667,
"name": "afatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "afatinib",
"approvalSource": "EMA & FDA (2013)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11524,
"name": "aficamten",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aficamten",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6786,
"name": "aflibercept",
"type": "Peptide",
"abbreviation": "",
"inn": "aflibercept",
"approvalSource": "FDA (2011), EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 198,
"name": "agomelatine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "agomelatine",
"approvalSource": "EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13766,
"name": "ainuovirine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8746,
"name": "ajmalicine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7386,
"name": "albiglutide",
"type": "Peptide",
"abbreviation": "",
"inn": "albiglutide",
"approvalSource": "FDA and EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7587,
"name": "alcaftadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alcaftadine",
"approvalSource": "FDA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7739,
"name": "alectinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alectinib",
"approvalSource": "FDA (2015), EMA (2017), Japan (unknown)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6787,
"name": "alefacept",
"type": "Peptide",
"abbreviation": "",
"inn": "alefacept",
"approvalSource": "FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6770,
"name": "alemtuzumab",
"type": "Antibody",
"abbreviation": "",
"inn": "alemtuzumab",
"approvalSource": "FDA (2001), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3141,
"name": "alendronate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alendronic acid",
"approvalSource": "FDA (1995), EMA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7108,
"name": "alfentanil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alfentanil",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7109,
"name": "alfuzosin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alfuzosin",
"approvalSource": "FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7561,
"name": "alglucosidase alfa",
"type": "Peptide",
"abbreviation": "",
"inn": "alglucosidase alfa",
"approvalSource": "EMA (2006), FDA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7237,
"name": "alimemazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alimemazine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6744,
"name": "alirocumab",
"type": "Antibody",
"abbreviation": "",
"inn": "alirocumab",
"approvalSource": "EMA & FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4812,
"name": "aliskiren",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aliskiren",
"approvalSource": "EMA & FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2645,
"name": "alitretinoin",
"type": "Metabolite",
"abbreviation": "",
"inn": "alitretinoin",
"approvalSource": "FDA (1999), EMA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11141,
"name": "alizapride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alizapride",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6795,
"name": "allopurinol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "allopurinol",
"approvalSource": "FDA (1966), EMA (2018)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7110,
"name": "almotriptan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "almotriptan",
"approvalSource": "FDA (2001), UK (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6319,
"name": "alogliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alogliptin",
"approvalSource": "EMA & FDA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2296,
"name": "alosetron",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alosetron",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7955,
"name": "alpelisib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alpelisib",
"approvalSource": "FDA (2019),EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7487,
"name": "alpha1-proteinase inhibitor",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6956,
"name": "alpha-methyltyrosine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "racemetirosine",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7111,
"name": "alprazolam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alprazolam",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 563,
"name": "alprenolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alprenolol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7373,
"name": "AlprolixTM",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7112,
"name": "altretamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "altretamine",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14185,
"name": "alverine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alverine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7471,
"name": "alvimopan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "alvimopan",
"approvalSource": "FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4128,
"name": "amantadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amantadine",
"approvalSource": "FDA (1966)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3951,
"name": "ambrisentan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ambrisentan",
"approvalSource": "FDA (2007), EMA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10692,
"name": "ambroxol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
11218
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7060,
"name": "amcinonide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amcinonide",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7565,
"name": "amfenac",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amfenac",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7564
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8032,
"name": "amifampridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amifampridine",
"approvalSource": "EMA (2009), FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10894,
"name": "amikacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amikacin",
"approvalSource": "FDA (1981), EMA (2020)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2421,
"name": "amiloride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amiloride",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7054,
"name": "aminoglutethimide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aminoglutethimide",
"approvalSource": "FDA (1980)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4810,
"name": "aminohippuric acid",
"type": "Metabolite",
"abbreviation": "PAH",
"inn": "",
"approvalSource": "FDA (1944)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2566,
"name": "amiodarone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amiodarone",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 963,
"name": "amisulpride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amisulpride",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 200,
"name": "amitriptyline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amitriptyline",
"approvalSource": "FDA (1961)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10505,
"name": "amivantamab",
"type": "Antibody",
"abbreviation": "",
"inn": "amivantamab",
"approvalSource": "FDA & EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7113,
"name": "amlexanox",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amlexanox",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6981,
"name": "amlodipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amlodipine",
"approvalSource": "FDA (1992), EMA (2007)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10018,
"name": "amodiaquine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amodiaquine",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14013,
"name": "amorolfine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 201,
"name": "amoxapine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amoxapine",
"approvalSource": "FDA (1980)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10895,
"name": "amoxicillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amoxicillin",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4804,
"name": "amphetamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amfetamine",
"approvalSource": "FDA (no history prior to 1976)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10896,
"name": "ampicillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ampicillin",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
12263,
12274,
12289,
12290,
12292,
12920
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12681,
"name": "amprenavir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amprenavir",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
12682
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11582,
"name": "anagliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "anagliptin",
"approvalSource": "Japan (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7114,
"name": "anagrelide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "anagrelide",
"approvalSource": "FDA (1997), EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6972,
"name": "anakinra",
"type": "Peptide",
"abbreviation": "",
"inn": "anakinra",
"approvalSource": "FDA (no history prior to 2001), EMA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 14127,
"name": "anamorelin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "anamorelin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5137,
"name": "anastrozole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "anastrozole",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7576,
"name": "andexanet alfa",
"type": "Peptide",
"abbreviation": "",
"inn": "andexanet alfa",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 2504,
"name": "angiotensin II",
"type": "Peptide",
"abbreviation": "",
"inn": "angiotensin II",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human, Mouse, Rat"
},
{
"ligandId": 8258,
"name": "anifrolumab",
"type": "Antibody",
"abbreviation": "",
"inn": "anifrolumab",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7115,
"name": "anileridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "anileridine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4133,
"name": "aniracetam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aniracetam",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6960,
"name": "anisindione",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "anisindione",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14403,
"name": "anrikefon",
"type": "Peptide",
"abbreviation": "",
"inn": "anrikefon",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7116,
"name": "antazoline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "antazoline",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14323,
"name": "antofloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "China NMPA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9043,
"name": "apalutamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "apalutamide",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6390,
"name": "apixaban",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "apixaban",
"approvalSource": "EMA (2011), FDA (2012)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 33,
"name": "apomorphine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "EMA (2001), FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13293,
"name": "aponermin",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "China (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7117,
"name": "apraclonidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "apraclonidine",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7372,
"name": "apremilast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "apremilast",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3490,
"name": "aprepitant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aprepitant",
"approvalSource": "FDA and EMA (2003)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7623
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10070,
"name": "aprocitentan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aprocitentan",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6570,
"name": "aprotinin",
"type": "Peptide",
"abbreviation": "",
"inn": "aprotinin",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Bovine"
},
{
"ligandId": 11744,
"name": "aranidipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aranidipine",
"approvalSource": "Japan (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7345,
"name": "arbekacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "arbekacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7479,
"name": "arformoterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6385,
"name": "argatroban",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "argatroban",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8271,
"name": "arimoclomol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "arimoclomol",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 34,
"name": "aripiprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aripiprazole",
"approvalSource": "FDA (2002), EMA (2004)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9955,
"name": "artemether",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "artemether",
"approvalSource": "FDA (2009) in combination with lumefantrine",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9957,
"name": "artenimol",
"type": "Natural product",
"abbreviation": "",
"inn": "artenimol",
"approvalSource": "EMA (2011) in combination with piperaquine",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9956,
"name": "artesunate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "artesunate",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8962,
"name": "asciminib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "asciminib",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 22,
"name": "asenapine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "asenapine",
"approvalSource": "FDA (2009), EMA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4139,
"name": "aspirin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (no history prior to 1965)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12293,
"name": "aspoxicillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aspoxicillin",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2603,
"name": "astemizole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "astemizole",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10882,
"name": "asunaprevir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "asunaprevir",
"approvalSource": "Japan (2014), Canada (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7341,
"name": "ataluren",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ataluren",
"approvalSource": "EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11138,
"name": "atazanavir",
"type": "Synthetic organic",
"abbreviation": "ATV",
"inn": "atazanavir",
"approvalSource": "FDA (2003), EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 548,
"name": "atenolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "atenolol",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7990,
"name": "atezolizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "atezolizumab",
"approvalSource": "FDA (2016), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9730,
"name": "atogepant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "atogepant",
"approvalSource": "FDA (2021), EMA & UK (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7118,
"name": "atomoxetine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "atomoxetine",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2949,
"name": "atorvastatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "atorvastatin",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6705,
7359
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2213,
"name": "atosiban",
"type": "Peptide",
"abbreviation": "",
"inn": "atosiban",
"approvalSource": "EMA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 9695,
"name": "atovaquone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "atovaquone",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9537,
"name": "atracurium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "atracurium besilate",
"approvalSource": "FDA (1983), UK (1999)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3487,
"name": "atrasentan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "atrasentan",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 320,
"name": "atropine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1973)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11136,
"name": "aumolertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aumolertinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6306,
"name": "auranofin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "auranofin",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12857,
"name": "avacincaptad pegol",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "avacincaptad pegol",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9450,
"name": "avacopan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "avacopan",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7448,
"name": "avanafil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "avanafil",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10368,
"name": "avapritinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "avapritinib",
"approvalSource": "FDA & EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9953,
"name": "avatrombopag",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "avatrombopag",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8735,
"name": "avelumab",
"type": "Antibody",
"abbreviation": "",
"inn": "avelumab",
"approvalSource": "EMA & FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10761,
"name": "avibactam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "avibactam",
"approvalSource": "FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
12949
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10891,
"name": "aviptadil",
"type": "Peptide",
"abbreviation": "",
"inn": "aviptadil",
"approvalSource": "Sweden (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 11867,
"name": "avutometinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "avutometinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13497,
"name": "axatilimab",
"type": "Antibody",
"abbreviation": "",
"inn": "axatilimab",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5659,
"name": "axitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "axitinib",
"approvalSource": "FDA and EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6796,
"name": "azacitidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azacitidine",
"approvalSource": "FDA (2004), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2285,
"name": "azasetron",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azasetron",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7119,
"name": "azatadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azatadine",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7120,
"name": "azathioprine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azathioprine",
"approvalSource": "FDA (1968), EMA (2021)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7226
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7484,
"name": "azelaic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azelaic acid",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7121,
"name": "azelastine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azelastine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12397,
"name": "azidamfenicol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azidamfenicol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6900,
"name": "azilsartan medoxomil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azilsartan medoxomil",
"approvalSource": "EMA & FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6901
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6510,
"name": "azithromycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azithromycin",
"approvalSource": "FDA & UK (1991)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": true,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12260,
"name": "azlocillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "azlocillin",
"approvalSource": "FDA",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10763,
"name": "aztreonam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "aztreonam",
"approvalSource": "FDA (1986), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12292,
"name": "bacampicillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bacampicillin",
"approvalSource": "FDA (1980)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10896
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12812,
"name": "bacitracin A",
"type": "Natural product",
"abbreviation": "",
"inn": "bacitracin",
"approvalSource": "FDA (1948)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1084,
"name": "baclofen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "baclofen",
"approvalSource": "FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13105,
"name": "balofloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "balofloxacin",
"approvalSource": "Korean FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11748,
"name": "baloxavir marboxil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "baloxavir marboxil",
"approvalSource": "Japan & FDA (2018), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11569,
"name": "balsalazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "balsalazide",
"approvalSource": "UK (1997), FDA (2000),",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2700
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6601,
"name": "bambuterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bambuterol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
560
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7792,
"name": "baricitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "baricitinib",
"approvalSource": "EMA (2017), FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6879,
"name": "basiliximab",
"type": "Antibody",
"abbreviation": "",
"inn": "basiliximab",
"approvalSource": "FDA (1998), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7355,
"name": "bazedoxifene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bazedoxifene",
"approvalSource": "EMA (2009), FDA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7059,
"name": "beclometasone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "beclometasone",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
5894
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5894,
"name": "beclometasone dipropionate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7059
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14392,
"name": "becotatug vedotin",
"type": "Antibody",
"abbreviation": "",
"inn": "becotatug vedotin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11171,
"name": "bedaquiline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bedaquiline",
"approvalSource": "FDA (2012), EMA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12951,
"name": "befotertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "befotertinib",
"approvalSource": "China NMPA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12863,
"name": "beinaglutide",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "China NMPA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 12182,
"name": "bekanamycin",
"type": "Natural product",
"abbreviation": "",
"inn": "bekanamycin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11117,
"name": "belantamab mafodotin",
"type": "Antibody",
"abbreviation": "",
"inn": "belantamab mafodotin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6892,
"name": "belatacept",
"type": "Peptide",
"abbreviation": "",
"inn": "belatacept",
"approvalSource": "FDA (2011), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6887,
"name": "belimumab",
"type": "Antibody",
"abbreviation": "",
"inn": "belimumab",
"approvalSource": "FDA (2011), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7496,
"name": "belinostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "belinostat",
"approvalSource": "FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9558,
"name": "belumosudil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11251,
"name": "belzutifan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "belzutifan",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8321,
"name": "bempedoic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bempedoic acid",
"approvalSource": "EMA & FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6374,
"name": "benazepril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benazepril",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6375
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6375,
"name": "benazeprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benazeprilat",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6374
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7478,
"name": "bendamustine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bendamustine",
"approvalSource": "FDA (2008), UK (2010)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7122,
"name": "bendroflumethiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bendroflumethiazide",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14184,
"name": "benfluorex",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benfluorex",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10159,
"name": "benidipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benidipine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13790,
"name": "benmelstobart",
"type": "Antibody",
"abbreviation": "",
"inn": "benmelstobart",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9215,
"name": "benperidol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benperidol",
"approvalSource": "UK (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7674,
"name": "benralizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "benralizumab",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5150,
"name": "benserazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benserazide",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7601,
"name": "benzatropine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benzatropine",
"approvalSource": "FDA (1954)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13477,
"name": "benzgalantamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benzgalantamine",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6693
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7611,
"name": "benzonatate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benzonatate",
"approvalSource": "FDA (1958)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14331,
"name": "(+)-benzphetamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7124,
"name": "benzquinamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benzquinamide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7125,
"name": "benzthiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benzthiazide",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7466,
"name": "bepotastine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bepotastine",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2337,
"name": "bepridil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bepridil",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11347,
"name": "berotralstat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "berotralstat",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12877,
"name": "besifloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "besifloxacin",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11937,
"name": "betahistine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "betahistine",
"approvalSource": "FDA (1970s)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7061,
"name": "betamethasone",
"type": "Metabolite",
"abbreviation": "",
"inn": "betamethasone",
"approvalSource": "FDA (1961)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7618,
"name": "betanidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "betanidine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 549,
"name": "betaxolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "betaxolol",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7126,
"name": "betazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "betazole",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 297,
"name": "bethanechol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (no history prior to 1948)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9602,
"name": "betrixaban",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "betrixaban",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6771,
"name": "bevacizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "bevacizumab",
"approvalSource": "FDA (2004), EMA (2005)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13953,
"name": "bevifibatide",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 12335,
"name": "bexagliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bexagliflozin",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2807,
"name": "bexarotene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bexarotene",
"approvalSource": "FDA (1999), EMA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2668,
"name": "bezafibrate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bezafibrate",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13334,
"name": "bezlotoxumab",
"type": "Antibody",
"abbreviation": "",
"inn": "bezlotoxumab",
"approvalSource": "FDA (2016), EMA (2017), Japan (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12022,
"name": "biapenem",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "biapenem",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2863,
"name": "bicalutamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bicalutamide",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11575,
"name": "bictegravir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bictegravir",
"approvalSource": "EMA & FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11742,
"name": "bifemelane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bifemelane",
"approvalSource": "Japan only",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11579,
"name": "bilastine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bilastine",
"approvalSource": "UK (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1958,
"name": "bimatoprost",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bimatoprost",
"approvalSource": "FDA (2001), EMA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
1959
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9411,
"name": "bimekizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "bimekizumab",
"approvalSource": "EMA (2021), FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7921,
"name": "binimetinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "binimetinib",
"approvalSource": "FDA and EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7128,
"name": "biperiden",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "biperiden",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14404,
"name": "bireociclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7129,
"name": "bisoprolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bisoprolol",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6470,
"name": "bivalirudin",
"type": "Peptide",
"abbreviation": "",
"inn": "bivalirudin",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7384,
"name": "blinatumomab",
"type": "Antibody",
"abbreviation": "",
"inn": "blinatumomab",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7670,
"name": "blonanserin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "blonanserin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7876,
"name": "boceprevir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "boceprevir",
"approvalSource": "EMA & FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6413,
"name": "borneol",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6391,
"name": "bortezomib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bortezomib",
"approvalSource": "FDA (2003), EMA (2004)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3494,
"name": "bosentan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bosentan",
"approvalSource": "FDA (2001), EMA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5710,
"name": "bosutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bosutinib",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4890,
"name": "brain natriuretic peptide",
"type": "Peptide",
"abbreviation": "BNP",
"inn": "nesiritide",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 10408,
"name": "bremelanotide",
"type": "Peptide",
"abbreviation": "",
"inn": "bremelanotide",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 9412,
"name": "brensocatib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "brensocatib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6772,
"name": "brentuximab vedotin",
"type": "Antibody",
"abbreviation": "",
"inn": "brentuximab vedotin",
"approvalSource": "FDA (2011), EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7130,
"name": "bretylium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bretylium tosilate",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7672,
"name": "brexpiprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "brexpiprazole",
"approvalSource": "FDA (2015), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7741,
"name": "brigatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "brigatinib",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 520,
"name": "brimonidine (UK14304)",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "brimonidine",
"approvalSource": "FDA (1996), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11556,
"name": "brincidofovir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "brincidofovir",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6797,
"name": "brinzolamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "brinzolamide",
"approvalSource": "FDA (1998), EMA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9041,
"name": "brivaracetam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "brivaracetam",
"approvalSource": "EMA & FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7540,
"name": "brodalumab",
"type": "Antibody",
"abbreviation": "",
"inn": "brodalumab",
"approvalSource": "Japan (2016), FDA (2017), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8713,
"name": "brolucizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "brolucizumab",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7131,
"name": "bromfenac",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bromfenac",
"approvalSource": "FDA (2004), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11218,
"name": "bromhexine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bromhexine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10692
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 35,
"name": "bromocriptine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bromocriptine",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7132,
"name": "bromodiphenhydramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bromazine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7133,
"name": "brompheniramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "brompheniramine",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7134,
"name": "buclizine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "buclizine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7434,
"name": "budesonide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "budesonide",
"approvalSource": "FDA (1997), EMA (2018)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7498,
"name": "bufexamac",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bufexamac",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12775,
"name": "bulevirtide",
"type": "Peptide",
"abbreviation": "",
"inn": "bulevirtide",
"approvalSource": "EMA (2020), UK HMRA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 4837,
"name": "bumetanide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bumetanide",
"approvalSource": "FDA (1983)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 570,
"name": "bunolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bunolol",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2397,
"name": "bupivacaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bupivacaine",
"approvalSource": "FDA (1972), EMA (2020)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 550,
"name": "bupranolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bupranolol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1670,
"name": "buprenorphine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "buprenorphine",
"approvalSource": "FDA (1981), EMA (2006)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7135,
"name": "bupropion",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "bupropion",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9292,
"name": "burosumab",
"type": "Antibody",
"abbreviation": "",
"inn": "burosumab",
"approvalSource": "EMA & FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3860,
"name": "buserelin",
"type": "Peptide",
"abbreviation": "",
"inn": "buserelin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 36,
"name": "buspirone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "buspirone",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7136,
"name": "busulfan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "busulfan",
"approvalSource": "FDA (1954), EMA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7137,
"name": "butabarbital",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "secbutabarbital",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7138,
"name": "butalbital",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "butalbital",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7591,
"name": "butorphanol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "butorphanol",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6798,
"name": "cabazitaxel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cabazitaxel",
"approvalSource": "FDA (2010), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 37,
"name": "cabergoline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cabergoline",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11386,
"name": "cabotegravir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cabotegravir",
"approvalSource": "EMA (2020), FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5887,
"name": "cabozantinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cabozantinib",
"approvalSource": "FDA (2012), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12966,
"name": "cadonilimab",
"type": "Antibody",
"abbreviation": "",
"inn": "cadonilimab",
"approvalSource": "China NMPA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 407,
"name": "caffeine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (no history prior to 1999), EMA (2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6921,
"name": "calcifediol",
"type": "Metabolite",
"abbreviation": "",
"inn": "calcifediol",
"approvalSource": "FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2778,
"name": "calcipotriol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "calcipotriol",
"approvalSource": "UK (1991), FDA (1993)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 685,
"name": "calcitonin",
"type": "Peptide",
"abbreviation": "CT",
"inn": "calcitonin",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 6973,
"name": "calcitonin (salmon)",
"type": "Peptide",
"abbreviation": "CT (salmon)",
"inn": "",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6432,
"name": "camostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "camostat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9758,
"name": "camrelizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "camrelizumab",
"approvalSource": "China (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4582,
"name": "canagliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "canagliflozin",
"approvalSource": "FDA & EMA (2013)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6773,
"name": "canakinumab",
"type": "Antibody",
"abbreviation": "",
"inn": "canakinumab",
"approvalSource": "FDA (2009), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 587,
"name": "candesartan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "candesartan",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
8352
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1776,
"name": "cangrelor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cangrelor",
"approvalSource": "FDA & EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4150,
"name": "cannabidiol",
"type": "Natural product",
"abbreviation": "CBD",
"inn": "cannabidiol",
"approvalSource": "FDA (2018), EMA (2019), UK (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13963,
"name": "canrenone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "canrenone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13081,
"name": "cantharidin",
"type": "Natural product",
"abbreviation": "",
"inn": "cantharidin",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6799,
"name": "capecitabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "capecitabine",
"approvalSource": "FDA (1998), EMA (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
4789
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7709,
"name": "capivasertib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "capivasertib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9123,
"name": "caplacizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "caplacizumab",
"approvalSource": "EMA (2018), FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7904,
"name": "capmatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "capmatinib",
"approvalSource": "FDA (2020), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13256,
"name": "capreomycin IB",
"type": "Natural product",
"abbreviation": "",
"inn": "capreomycin",
"approvalSource": "UK, FDA (1971)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6878,
"name": "capromab",
"type": "Antibody",
"abbreviation": "",
"inn": "capromab",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2486,
"name": "capsaicin",
"type": "Natural product",
"abbreviation": "",
"inn": "capsaicin",
"approvalSource": "EMA & FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5158,
"name": "captopril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "captopril",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 569,
"name": "carazolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carazolol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 298,
"name": "carbachol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carbachol",
"approvalSource": "FDA (1972)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5339,
"name": "carbamazepine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carbamazepine",
"approvalSource": "FDA (1968)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10768,
"name": "carbenicillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carbenicillin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
12276,
12288
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11169,
"name": "carbetocin",
"type": "Peptide",
"abbreviation": "",
"inn": "carbetocin",
"approvalSource": "UK (2007)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 5159,
"name": "carbidopa",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carbidopa",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7139,
"name": "carbinoxamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carbinoxamine",
"approvalSource": "FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7624,
"name": "carboplatin",
"type": "Inorganic",
"abbreviation": "",
"inn": "carboplatin",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12288,
"name": "carfecillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carfecillin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10768
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7420,
"name": "carfilzomib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carfilzomib",
"approvalSource": "FDA (2012), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7458,
"name": "carglumic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carglumic acid",
"approvalSource": "EMA (2003), FDA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12276,
"name": "carindacillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carindacillin",
"approvalSource": "FDA (1972)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10768
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7671,
"name": "cariprazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cariprazine",
"approvalSource": "FDA (2015), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7610,
"name": "carisoprodol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carisoprodol",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7225
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6800,
"name": "carmustine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carmustine",
"approvalSource": "FDA (1977), EMA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10510,
"name": "carotegrast methyl",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carotegrast",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10511
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7140,
"name": "carphenazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carfenazine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7141,
"name": "carprofen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carprofen",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7142,
"name": "carteolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carteolol",
"approvalSource": "FDA (1988)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12296,
"name": "carumonam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carumonam",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 551,
"name": "carvedilol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "carvedilol",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11444,
"name": "casimersen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "casimersen",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11327,
"name": "casirivimab",
"type": "Antibody",
"abbreviation": "",
"inn": "casirivimab",
"approvalSource": "Japan, EMA and UK MHRA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9601,
"name": "catequentinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "catequentinib",
"approvalSource": "China (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7385,
"name": "catumaxomab",
"type": "Antibody",
"abbreviation": "",
"inn": "catumaxomab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11101,
"name": "cedazuridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cedazuridine",
"approvalSource": "FDA (2020), EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10897,
"name": "cefaclor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefaclor",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4831,
"name": "cefadroxil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefadroxil",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12193,
"name": "cefaloglycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefaloglycin",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8798,
"name": "cefalotin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefalotin",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12210,
"name": "cefamandole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefamandole",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12191,
"name": "cefapirin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefapirin",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10935,
"name": "cefazolin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefazolin",
"approvalSource": "FDA (1973)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12053,
"name": "cefcapene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefcapene",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12023,
"name": "cefdinir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefdinir",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12030,
"name": "cefditoren",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefditoren",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10772,
"name": "cefepime",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefepime",
"approvalSource": "FDA (1996), UK (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10776,
"name": "cefiderocol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefiderocol",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10898,
"name": "cefixime",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefixime",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12024,
"name": "cefmenoxime",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefmenoxime",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12215,
"name": "cefmetazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefmetazole",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12217,
"name": "cefonicid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefonicid",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12025,
"name": "cefoperazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefoperazone",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12218,
"name": "ceforanide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceforanide",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12034,
"name": "cefoselis",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefoselis",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10893,
"name": "cefotaxime",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefotaxime",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10936,
"name": "cefotetan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefotetan",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10937,
"name": "cefoxitin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefoxitin",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12054,
"name": "cefozopran",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefozopran",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12027,
"name": "cefpiramide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefpiramide",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12033,
"name": "cefpirome",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefpirome",
"approvalSource": "Thailand (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10780,
"name": "cefpodoxime",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefpodoxime",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12219,
"name": "cefprozil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefprozil",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13619,
"name": "cefroxadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefroxadine",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10899,
"name": "ceftaroline fosamil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceftaroline fosamil",
"approvalSource": "FDA (2010), EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10762,
"name": "ceftazidime",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceftazidime",
"approvalSource": "UK (1983), FDA (1985)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11051,
"name": "cefteram",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefteram",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12029,
"name": "ceftibuten",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceftibuten",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10785,
"name": "ceftizoxime",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceftizoxime",
"approvalSource": "FDA (1983)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
10786
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10787,
"name": "ceftobiprole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceftobiprole",
"approvalSource": "UK (2013), FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10788,
"name": "ceftolozane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceftolozane",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5326,
"name": "ceftriaxone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceftriaxone",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10900,
"name": "cefuroxime",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefuroxime",
"approvalSource": "FDA (1983)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2892,
"name": "celecoxib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "celecoxib",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9064,
"name": "celiprolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "celiprolol",
"approvalSource": "UK (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10090,
"name": "cemiplimab",
"type": "Antibody",
"abbreviation": "",
"inn": "cemiplimab",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10773,
"name": "cenobamate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cenobamate",
"approvalSource": "FDA (2019), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4832,
"name": "cephalexin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefalexin",
"approvalSource": "FDA (1971, prior history not available)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4830,
"name": "cephradine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cefradine",
"approvalSource": "FDA (1974, prior history not available)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7397,
"name": "ceritinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceritinib",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2950,
"name": "cerivastatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cerivastatin",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6774,
"name": "certolizumab pegol",
"type": "Antibody",
"abbreviation": "",
"inn": "certolizumab pegol",
"approvalSource": "FDA (2008), EMA (2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7589,
"name": "ceruletide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ceruletide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13952,
"name": "cetagliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11433,
"name": "cetilistat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cetilistat",
"approvalSource": "Japan (213)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1222,
"name": "cetirizine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cetirizine",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1190,
"name": "cetrorelix",
"type": "Peptide",
"abbreviation": "",
"inn": "cetrorelix",
"approvalSource": "EMA (1999), FDA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6882,
"name": "cetuximab",
"type": "Antibody",
"abbreviation": "",
"inn": "cetuximab",
"approvalSource": "Switzerland (2003), EMA & FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9658,
"name": "cevimeline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cevimeline",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 608,
"name": "chenodeoxycholic acid",
"type": "Metabolite",
"abbreviation": "CDCA",
"inn": "chenodeoxycholic acid",
"approvalSource": "FDA (1983), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12287,
"name": "chiglitazar",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "China (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7324,
"name": "chlophedianol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clofedanol",
"approvalSource": "FDA (date unknown)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7143,
"name": "chlorambucil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlorambucil",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10901,
"name": "chloramphenicol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chloramphenicol",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3370,
"name": "chlordiazepoxide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlordiazepoxide",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14052,
"name": "chlorhexidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlorhexidine",
"approvalSource": "FDA (1976), UK",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7323,
"name": "chlormezanone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlormezanone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7145,
"name": "chloroprocaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chloroprocaine",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5535,
"name": "chloroquine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chloroquine",
"approvalSource": "FDA (1949), UK (2000)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4835,
"name": "chlorothiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlorothiazide",
"approvalSource": "FDA (1958)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7146,
"name": "chlorotrianisene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlorotrianisene",
"approvalSource": "FDA (date unknown)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6976,
"name": "chlorpheniramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlorphenamine",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 83,
"name": "chlorpromazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlorpromazine",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6801,
"name": "chlorpropamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlorpropamide",
"approvalSource": "FDA (1958)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11976,
"name": "chlorprothixene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlorprothixene",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13537,
"name": "chlortetracycline",
"type": "Natural product",
"abbreviation": "",
"inn": "chlortetracycline",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7147,
"name": "chlorthalidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlortalidone",
"approvalSource": "FDA (1960), UK (1998)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2322,
"name": "chlorzoxazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlorzoxazone",
"approvalSource": "FDA (1958)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 609,
"name": "cholic acid",
"type": "Metabolite",
"abbreviation": "CA",
"inn": "",
"approvalSource": "EMA (2013), FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7469,
"name": "ciclesonide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ciclesonide",
"approvalSource": "FDA (2006)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11349,
"name": "ciclopirox",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ciclopirox",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5166,
"name": "cilastatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cilastatin",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6459,
"name": "cilazapril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cilazapril",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6461
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6461,
"name": "cilazaprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cilazaprilat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6459
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11329,
"name": "cilgavimab",
"type": "Antibody",
"abbreviation": "",
"inn": "cilgavimab",
"approvalSource": "EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7767,
"name": "cilnidipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cilnidipine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7148,
"name": "cilostazol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cilostazol",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1231,
"name": "cimetidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cimetidine",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3308,
"name": "cinacalcet",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cinacalcet",
"approvalSource": "EMA & FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9072,
"name": "cinnarizine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cinnarizine clofibrate",
"approvalSource": "UK (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12401,
"name": "cinoxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cinoxacin",
"approvalSource": "UK (1979), FDA (1980)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3438,
"name": "ciprofibrate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ciprofibrate",
"approvalSource": "UK (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10902,
"name": "ciprofloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ciprofloxacin",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 240,
"name": "cisapride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cisapride",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5343,
"name": "cisplatin",
"type": "Inorganic",
"abbreviation": "",
"inn": "cisplatin",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7547,
"name": "citalopram",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "citalopram",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4799,
"name": "cladribine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cladribine",
"approvalSource": "FDA (1993), EMA (2004)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10903,
"name": "clarithromycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clarithromycin",
"approvalSource": "FDA (1991), UK (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11215,
"name": "clascoterone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clascoterone",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11128,
"name": "clavulanic acid",
"type": "Natural product",
"abbreviation": "",
"inn": "clavulanic acid",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12286,
"name": "clazosentan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clazosentan",
"approvalSource": "Japan (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6063,
"name": "clemastine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clemastine",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7468,
"name": "clevidipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clevidipine",
"approvalSource": "FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 366,
"name": "clidinium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clidinium bromide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10607,
"name": "clindamycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clindamycin",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7149,
"name": "clobazam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clobazam",
"approvalSource": "FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7062,
"name": "clobetasol propionate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clobetasol",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9088,
"name": "clobetasone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clobetasone",
"approvalSource": "UK (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9605,
"name": "clodronic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clodronic acid",
"approvalSource": "UK (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6802,
"name": "clofarabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clofarabine",
"approvalSource": "FDA (2004), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9184,
"name": "clofazimine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clofazimine",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2667,
"name": "clofibrate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clofibrate",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12926,
"name": "clofoctol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clofoctol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4159,
"name": "clomiphene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clomifene",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2398,
"name": "clomipramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clomipramine",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13541,
"name": "clomocycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clomocycline",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6963,
"name": "clonazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clonazepam",
"approvalSource": "FDA (1975)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 516,
"name": "clonidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clonidine",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7150,
"name": "clopidogrel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clopidogrel",
"approvalSource": "FDA (1997), EMA (1998)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
1772
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7548,
"name": "clorazepate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dipotassium clorazepate",
"approvalSource": "FDA (1972)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2330,
"name": "clotrimazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clotrimazole",
"approvalSource": "FDA (1975)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11126,
"name": "cloxacillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cloxacillin",
"approvalSource": "FDA (1971)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 38,
"name": "clozapine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "clozapine",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7535,
"name": "cobicistat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cobicistat",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7626,
"name": "cobimetinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cobimetinib",
"approvalSource": "FDA & EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2286,
"name": "cocaine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1673,
"name": "codeine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (no history prior to 2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13765,
"name": "cofrogliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cofrogliptin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2367,
"name": "colchicine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2799,
"name": "colfosceril palmitate",
"type": "Metabolite",
"abbreviation": "",
"inn": "colfosceril palmitate",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10794,
"name": "colistin",
"type": "Natural product",
"abbreviation": "",
"inn": "colistin",
"approvalSource": "UK (2006)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11182,
"name": "concizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "concizumab",
"approvalSource": "Health Canada (2023), FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7627,
"name": "conestat alfa",
"type": "Peptide",
"abbreviation": "",
"inn": "conestat alfa",
"approvalSource": "EMA (2010), FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 2203,
"name": "conivaptan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "conivaptan",
"approvalSource": "FDA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10795,
"name": "contezolid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "contezolid",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
10796
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7875,
"name": "copanlisib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "copanlisib",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 508,
"name": "corbadrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "corbadrine",
"approvalSource": "FDA (1960), in combination with mepivacaine hydrochloride",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6967,
"name": "corticotropin zinc hydroxide",
"type": "Peptide",
"abbreviation": "",
"inn": "corticotropin zinc hydroxide",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 2868,
"name": "cortisol",
"type": "Metabolite",
"abbreviation": "",
"inn": "hydrocortisone",
"approvalSource": "FDA (1953, prior history unavailable), EMA (2011)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13676,
"name": "cosibelimab",
"type": "Antibody",
"abbreviation": "",
"inn": "cosibelimab",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6965,
"name": "cosyntropin",
"type": "Peptide",
"abbreviation": "",
"inn": "tetracosactide",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 3533,
"name": "crinecerfont",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "crinecerfont",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9151,
"name": "crisaborole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "crisaborole",
"approvalSource": "FDA (2016), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7347,
"name": "crisantaspase",
"type": "Peptide",
"abbreviation": "",
"inn": "crisantaspase",
"approvalSource": "FDA (no history prior to 2011), EMA (2023)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 13764,
"name": "crisugabalin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "crisugabalin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10550,
"name": "crizanlizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "crizanlizumab",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4903,
"name": "crizotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "crizotinib",
"approvalSource": "FDA (2011), EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7453,
"name": "crofelemer",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7608,
"name": "cromoglicic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cromoglicic acid",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11165,
"name": "Crotamiton",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "crotamiton",
"approvalSource": "FDA (1955), UK (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12790,
"name": "crovalimab",
"type": "Antibody",
"abbreviation": "",
"inn": "crovalimab",
"approvalSource": "China NMPA, FDA & EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12077,
"name": "culmerciclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "culmerciclib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4817,
"name": "cyclacillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ciclacillin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7151,
"name": "cyclizine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cyclizine",
"approvalSource": "FDA (date unknown)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7152,
"name": "cyclobenzaprine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cyclobenzaprine",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7899,
"name": "cyclopenthiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cyclopenthiazide",
"approvalSource": "UK (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7153,
"name": "cyclopentolate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cyclopentolate",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7154,
"name": "cyclophosphamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cyclophosphamide",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1024,
"name": "cyclosporin A",
"type": "Peptide",
"abbreviation": "",
"inn": "ciclosporin",
"approvalSource": "FDA and UK (1983), EMA (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 4167,
"name": "cyclothiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cyclothiazide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 277,
"name": "cyproheptadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cyproheptadine",
"approvalSource": "FDA (1961)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2865,
"name": "cyproterone acetate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4827,
"name": "cytarabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cytarabine",
"approvalSource": "FDA (1969), EMA (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6379,
"name": "dabigatran etexilate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dabigatran etexilate",
"approvalSource": "EMA (2008), FDA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6380
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6494,
"name": "dabrafenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dabrafenib",
"approvalSource": "FDA and EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9075,
"name": "dacarbazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dacarbazine",
"approvalSource": "FDA (1975)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11266,
"name": "daclatasvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "daclatasvir",
"approvalSource": "EMA (2014), FDA (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6880,
"name": "daclizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "daclizumab",
"approvalSource": "FDA FDA (1997), EMA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7422,
"name": "dacomitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dacomitinib",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10876,
"name": "dalbavancin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dalbavancin",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10797,
"name": "dalfopristin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dalfopristin",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11189,
"name": "dalpiciclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dalpiciclib",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6803,
"name": "dalteparin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dalteparin sodium",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6804,
"name": "danaparoid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "danaparoid sodium",
"approvalSource": "FDA (1996), still marketed outside the U.S.",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6942,
"name": "danazol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "danazol",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11988,
"name": "danicopan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "danicopan",
"approvalSource": "Japan PMDA, FDA and EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4172,
"name": "dantrolene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dantrolene",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4594,
"name": "dapagliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dapagliflozin",
"approvalSource": "EMA (2012), FDA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7155,
"name": "dapiprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dapiprazole",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7901,
"name": "dapoxetine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dapoxetine",
"approvalSource": "UK (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8455,
"name": "daprodustat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "daprodustat",
"approvalSource": "Japan (2020), FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10934,
"name": "dapsone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dapsone",
"approvalSource": "FDA (1979), UK (1988)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10904,
"name": "daptomycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "daptomycin",
"approvalSource": "FDA (2003), EMA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7395,
"name": "daratumumab",
"type": "Antibody",
"abbreviation": "",
"inn": "daratumumab",
"approvalSource": "FDA (2015), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11648,
"name": "daridorexant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "daridorexant",
"approvalSource": "FDA & EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 321,
"name": "darifenacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "darifenacin",
"approvalSource": "EMA & FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10439,
"name": "darolutamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "darolutamide",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11243,
"name": "darunavir",
"type": "Synthetic organic",
"abbreviation": "DRV",
"inn": "darunavir",
"approvalSource": "FDA (2006), EMA (2007)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11270,
"name": "dasabuvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dasabuvir",
"approvalSource": "EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5678,
"name": "dasatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dasatinib",
"approvalSource": "FDA & EMA (2006)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13304,
"name": "datopotamab deruxtecan",
"type": "Antibody",
"abbreviation": "",
"inn": "datopotamab deruxtecan",
"approvalSource": "FDA (2025)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7063,
"name": "daunorubicin",
"type": "Natural product",
"abbreviation": "",
"inn": "daunorubicin",
"approvalSource": "FDA (1979), EMA (2018)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9489,
"name": "D-cycloserine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cycloserine",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6805,
"name": "decitabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "decitabine",
"approvalSource": "FDA (2006), EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7910,
"name": "defactinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "defactinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7456,
"name": "deferiprone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "deferiprone",
"approvalSource": "EMA (1999), FDA (2011)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9087,
"name": "defibrotide",
"type": "Natural product",
"abbreviation": "",
"inn": "defibrotide",
"approvalSource": "EMA (2013), FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9477,
"name": "deflazacort",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "UK (1994), FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5585,
"name": "degarelix",
"type": "Peptide",
"abbreviation": "",
"inn": "degarelix",
"approvalSource": "FDA (2008), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 2370,
"name": "dehydroepiandrosterone",
"type": "Metabolite",
"abbreviation": "DHEA",
"inn": "prasterone",
"approvalSource": "FDA (2016), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10799,
"name": "delafloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "delafloxacin",
"approvalSource": "FDA (2017), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12876,
"name": "delamanid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "delamanid",
"approvalSource": "EMA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12674,
"name": "delavirdine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "delavirdine",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9619,
"name": "delgocitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "delgocitinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2424,
"name": "Δ9-tetrahydrocannabinol",
"type": "Natural product",
"abbreviation": "THC",
"inn": "dronabinol",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10905,
"name": "demeclocycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "demeclocycline",
"approvalSource": "FDA (1960), UK (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7044,
"name": "denileukin diftitox",
"type": "Peptide",
"abbreviation": "",
"inn": "denileukin diftitox",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6886,
"name": "denosumab",
"type": "Antibody",
"abbreviation": "",
"inn": "denosumab",
"approvalSource": "FDA and EMA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 610,
"name": "deoxycholic acid",
"type": "Metabolite",
"abbreviation": "DCA",
"inn": "",
"approvalSource": "FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14305,
"name": "depemokimab",
"type": "Antibody",
"abbreviation": "",
"inn": "depemokimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7064,
"name": "deserpidine",
"type": "Natural product",
"abbreviation": "",
"inn": "deserpidine",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7156,
"name": "desflurane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "desflurane",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2399,
"name": "desipramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "desipramine",
"approvalSource": "FDA (no history prior to 1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6458,
"name": "desirudin",
"type": "Peptide",
"abbreviation": "",
"inn": "desirudin",
"approvalSource": "FDA (no history prior to 2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6806,
"name": "deslanoside",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "deslanoside",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7157,
"name": "desloratadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "desloratadine",
"approvalSource": "FDA and EMA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2182,
"name": "desmopressin",
"type": "Peptide",
"abbreviation": "",
"inn": "desmopressin",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7065,
"name": "desogestrel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "desogestrel",
"approvalSource": "FDA (1992), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7590
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7066,
"name": "desonide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "desonide",
"approvalSource": "FDA (1972)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7067,
"name": "desoximetasone",
"type": "Metabolite",
"abbreviation": "",
"inn": "desoximetasone",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7158,
"name": "desvenlafaxine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "desvenlafaxine",
"approvalSource": "FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10432,
"name": "deucravacitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "deucravacitinib",
"approvalSource": "FDA (2022), EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11410,
"name": "deuruxolitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "deuruxolitinib",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14402,
"name": "deutenzalutamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "deutenzalutamide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8707,
"name": "deutetrabenazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "deutetrabenazine",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13695,
"name": "deutivacaftor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "deutivacaftor",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2768,
"name": "dexamethasone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dexamethasone",
"approvalSource": "FDA (1958), EMA (2010)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2147,
"name": "dexamfetamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dexamfetamine",
"approvalSource": "FDA (1955, in complex; 1975 as Dextroamphetamine sulphate)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7213
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7588,
"name": "dexbrompheniramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dexbrompheniramine",
"approvalSource": "FDA",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 354,
"name": "dexetimide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benzetimide,dexetimide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5487,
"name": "dexlansoprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dexlansoprazole,lansoprazole",
"approvalSource": "FDA (2009); (1995 as lansoprazole)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 521,
"name": "dexmedetomidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dexmedetomidine",
"approvalSource": "FDA (1999), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7554,
"name": "dexmethylphenidate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dexmethylphenidate",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
11450
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7330,
"name": "dexrazoxane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dexrazoxane",
"approvalSource": "FDA (1995), EMA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6953,
"name": "dextromethorphan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dextromethorphan",
"approvalSource": "FDA (no history prior to 1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7593,
"name": "dextropropoxyphene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dextropropoxyphene",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6951,
"name": "dextrothyroxine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dextrothyroxine sodium",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10800,
"name": "diacerein",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diacerein",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3364,
"name": "diazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diazepam",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2409,
"name": "diazoxide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diazoxide",
"approvalSource": "FDA (1973)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12134,
"name": "dibekacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dibekacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7159,
"name": "dibucaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cinchocaine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2714,
"name": "diclofenac",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diclofenac",
"approvalSource": "FDA (1988)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6807,
"name": "diclofenamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diclofenamide",
"approvalSource": "FDA (1958)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12261,
"name": "dicloxacillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dicloxacillin",
"approvalSource": "FDA (1968)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6808,
"name": "dicumarol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1944)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 355,
"name": "dicyclomine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dicycloverine",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4833,
"name": "didanosine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "didanosine",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7160,
"name": "dienestrol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dienestrol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7654,
"name": "dienogest",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dienogest",
"approvalSource": "FDA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7161,
"name": "diethylpropion",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amfepramone",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7398
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2801,
"name": "diethylstilbestrol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diethylstilbestrol",
"approvalSource": "FDA (1973)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9776,
"name": "difamilast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "difamilast",
"approvalSource": "Japan (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9044,
"name": "difelikefalin",
"type": "Peptide",
"abbreviation": "",
"inn": "difelikefalin",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7592,
"name": "difenoxin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "difenoxin",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7068,
"name": "diflorasone diacetate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diflorasone",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7162,
"name": "diflunisal",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diflunisal",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7474,
"name": "difluprednate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "difluprednate",
"approvalSource": "FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6782,
"name": "digitoxin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "digitoxin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4726,
"name": "digoxin",
"type": "Natural product",
"abbreviation": "",
"inn": "digoxin",
"approvalSource": "FDA (no history prior to 1975)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7594,
"name": "dihydrocodeine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dihydrocodeine",
"approvalSource": "FDA (1958, as bitartrate with aspirin and caffeine)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 121,
"name": "dihydroergotamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dihydroergotamine",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12163,
"name": "dihydrostreptomycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dihydrostreptomycin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2298,
"name": "diltiazem",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diltiazem",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7045,
"name": "dimethyl fumarate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
5786
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10101,
"name": "dimetindene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dimetindene",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7979,
"name": "dinutuximab",
"type": "Antibody",
"abbreviation": "",
"inn": "dinutuximab",
"approvalSource": "FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1224,
"name": "diphenhydramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diphenhydramine",
"approvalSource": "FDA (1946)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7163,
"name": "diphenidol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "difenidol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7164,
"name": "diphenoxylate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diphenoxylate",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7165,
"name": "diphenylpyraline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diphenylpyraline",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9081,
"name": "dipipanone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dipipanone",
"approvalSource": "UK (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7166,
"name": "dipivefrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dipivefrine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
509
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4807,
"name": "dipyridamole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dipyridamole",
"approvalSource": "FDA (1961)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12928,
"name": "dirithromycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dirithromycin",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10525,
"name": "diroximel fumarate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "diroximel fumarate",
"approvalSource": "FDA (2019), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
5786
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13811,
"name": "dirozalkib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dirozalkib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13716,
"name": "disitamab vedotin",
"type": "Antibody",
"abbreviation": "",
"inn": "disitamab vedotin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7167,
"name": "disopyramide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "disopyramide",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7168,
"name": "disulfiram",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "disulfiram",
"approvalSource": "FDA (1951)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13087,
"name": "divozilimab",
"type": "Antibody",
"abbreviation": "",
"inn": "divozilimab",
"approvalSource": "Russia (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 535,
"name": "dobutamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dobutamine",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6809,
"name": "docetaxel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "docetaxel",
"approvalSource": "FDA (1996), EMA (1995)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2604,
"name": "dofetilide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dofetilide",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7365,
"name": "dolutegravir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dolutegravir",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 965,
"name": "domperidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "domperidone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8357,
"name": "donanemab",
"type": "Antibody",
"abbreviation": "",
"inn": "donanemab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6599,
"name": "donepezil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "donepezil",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13610,
"name": "donidalorsen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "donidalorsen",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 940,
"name": "dopamine",
"type": "Metabolite",
"abbreviation": "",
"inn": "dopamine",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12679,
"name": "doravirine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "doravirine",
"approvalSource": "FDA & EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9978,
"name": "dordaviprone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dordaviprone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12183,
"name": "doripenem",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "doripenem",
"approvalSource": "FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12124,
"name": "dorzagliatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dorzagliatin",
"approvalSource": "China (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6810,
"name": "dorzolamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dorzolamide",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11518,
"name": "dostarlimab",
"type": "Antibody",
"abbreviation": "",
"inn": "dostarlimab",
"approvalSource": "EMA & FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7549,
"name": "dosulepin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dosulepin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11389,
"name": "dotinurad",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dotinurad",
"approvalSource": "Japan (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7169,
"name": "doxapram",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "doxapram",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7170,
"name": "doxazosin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "doxazosin",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1225,
"name": "doxepin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "doxepin",
"approvalSource": "FDA (1969)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2790,
"name": "doxercalciferol",
"type": "Metabolite",
"abbreviation": "",
"inn": "doxercalciferol",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7069,
"name": "doxorubicin",
"type": "Natural product",
"abbreviation": "",
"inn": "doxorubicin",
"approvalSource": "FDA (1974), EMA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6464,
"name": "doxycycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "doxycycline",
"approvalSource": "FDA (1967), UK (2000)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": true,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7171,
"name": "doxylamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "doxylamine",
"approvalSource": "FDA (1948)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6947,
"name": "dromostanolone propionate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "drostanolone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7465,
"name": "dronedarone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dronedarone",
"approvalSource": "FDA and EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7172,
"name": "droperidol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "droperidol",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2874,
"name": "drospirenone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "drospirenone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6788,
"name": "drotrecogin alfa",
"type": "Peptide",
"abbreviation": "",
"inn": "drotrecogin alfa (activated)",
"approvalSource": "FDA (2001), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7391,
"name": "droxidopa",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "droxidopa",
"approvalSource": "FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
505
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7638,
"name": "dulaglutide",
"type": "Peptide",
"abbreviation": "",
"inn": "dulaglutide",
"approvalSource": "EMA & FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 202,
"name": "duloxetine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "duloxetine",
"approvalSource": "FDA & EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7574,
"name": "dupilumab",
"type": "Antibody",
"abbreviation": "",
"inn": "dupilumab",
"approvalSource": "EMA & FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12693,
"name": "durlobactam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "durlobactam",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7985,
"name": "durvalumab",
"type": "Antibody",
"abbreviation": "",
"inn": "durvalumab",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7457,
"name": "dutasteride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dutasteride",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7795,
"name": "duvelisib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "duvelisib",
"approvalSource": "FDA (2018), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7173,
"name": "dyclonine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dyclonine",
"approvalSource": "FDA (date unknown)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2878,
"name": "dydrogesterone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dydrogesterone",
"approvalSource": "FDA-no information available-discontinued",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7070,
"name": "dyphylline",
"type": "Metabolite",
"abbreviation": "",
"inn": "diprophylline",
"approvalSource": "FDA (1951)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13875,
"name": "ebdarokimab",
"type": "Antibody",
"abbreviation": "",
"inn": "ebdarokimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13786,
"name": "ebronucimab",
"type": "Antibody",
"abbreviation": "",
"inn": "ebronucimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6955,
"name": "ecallantide",
"type": "Peptide",
"abbreviation": "",
"inn": "ecallantide",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 9074,
"name": "echothiophate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2446,
"name": "econazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "econazole",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6884,
"name": "eculizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "eculizumab",
"approvalSource": "FDA (2011), EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5638,
"name": "edotreotide",
"type": "Peptide",
"abbreviation": "",
"inn": "edotreotide",
"approvalSource": "EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7575,
"name": "edoxaban",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "edoxaban",
"approvalSource": "EMA & FDA (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7984,
"name": "edrecolomab",
"type": "Antibody",
"abbreviation": "",
"inn": "edrecolomab",
"approvalSource": "Germany (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9073,
"name": "edrophonium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "edrophonium chloride",
"approvalSource": "FDA (1951)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6593,
"name": "efalizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "efalizumab",
"approvalSource": "FDA (2003), EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13086,
"name": "efanesoctocog alfa",
"type": "Peptide",
"abbreviation": "",
"inn": "efanesoctocog alfa",
"approvalSource": "FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 11287,
"name": "efavirenz",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "efavirenz",
"approvalSource": "FDA (1998), EMA (1999)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9777,
"name": "efgartigimod alfa",
"type": "Antibody",
"abbreviation": "",
"inn": "efgartigimod alfa",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12180,
"name": "eflapegrastim",
"type": "Peptide",
"abbreviation": "",
"inn": "eflapegrastim",
"approvalSource": "FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 5176,
"name": "eflornithine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eflornithine",
"approvalSource": "FDA (2000), EMA (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12565,
"name": "efonidipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "efonidipine",
"approvalSource": "Japan (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12339,
"name": "elacestrant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "elacestrant",
"approvalSource": "FDA & EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11135,
"name": "elafibranor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "elafibranor",
"approvalSource": "EMA & FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8362,
"name": "elagolix",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "elagolix",
"approvalSource": "FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14276,
"name": "elamipretide",
"type": "Peptide",
"abbreviation": "",
"inn": "elamipretide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 2783,
"name": "eldecalcitol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eldecalcitol",
"approvalSource": "Japan only",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 40,
"name": "eletriptan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eletriptan",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10552,
"name": "elexacaftor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "elexacaftor",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7536,
"name": "eliglustat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eliglustat",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12691,
"name": "elinzanetant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "elinzanetant",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9996,
"name": "elobixibat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "elobixibat",
"approvalSource": "Japan (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7392,
"name": "elosulfase alfa",
"type": "Peptide",
"abbreviation": "",
"inn": "elosulfase alfa",
"approvalSource": "EMA & FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 8361,
"name": "elotuzumab",
"type": "Antibody",
"abbreviation": "",
"inn": "elotuzumab",
"approvalSource": "FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12889,
"name": "elranatamab",
"type": "Antibody",
"abbreviation": "",
"inn": "elranatamab",
"approvalSource": "FDA & EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6961,
"name": "eltrombopag",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eltrombopag",
"approvalSource": "FDA (2008), EMA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7691,
"name": "eluxadoline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eluxadoline",
"approvalSource": "FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11574,
"name": "elvitegravir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "elvitegravir",
"approvalSource": "EMA (2013), FDA (2014), UK (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9295,
"name": "emapalumab",
"type": "Antibody",
"abbreviation": "",
"inn": "emapalumab",
"approvalSource": "FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7174,
"name": "emedastine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "emedastine",
"approvalSource": "FDA (1997), EMA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9744,
"name": "emicizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "emicizumab",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4754,
"name": "empagliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "empagliflozin",
"approvalSource": "FDA & EMA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11244,
"name": "emtricitabine",
"type": "Synthetic organic",
"abbreviation": "FTC",
"inn": "emtricitabine",
"approvalSource": "EMA & FDA (2003)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6322,
"name": "enalapril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enalapril",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6332
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6332,
"name": "enalaprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enalaprilat",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6322
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11828,
"name": "enarodustat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enarodustat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8960,
"name": "enasidenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enasidenib",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11905,
"name": "enavogliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enavogliflozin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7908,
"name": "encorafenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "encorafenib",
"approvalSource": "FDA and EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7175,
"name": "enflurane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enflurane",
"approvalSource": "FDA (1972)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10738,
"name": "enfortumab vedotin",
"type": "Antibody",
"abbreviation": "",
"inn": "enfortumab vedotin",
"approvalSource": "FDA (2019), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13789,
"name": "enlonstobart",
"type": "Antibody",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12188,
"name": "enmetazobactam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enmetazobactam",
"approvalSource": "FDA & EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8882,
"name": "enoxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enoxacin",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6811,
"name": "enoxaparin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enoxaparin sodium",
"approvalSource": "FDA (1993), FDA (2016)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9063,
"name": "enoximone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enoximone",
"approvalSource": "UK",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8959,
"name": "ensartinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ensartinib",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11865,
"name": "ensifentrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ensifentrine",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11871,
"name": "ensitrelvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ensitrelvir",
"approvalSource": "Japan (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6647,
"name": "entacapone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "entacapone",
"approvalSource": "FDA (1999), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7007,
"name": "entinostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "entinostat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8290,
"name": "entrectinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "entrectinib",
"approvalSource": "Japan and FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10492,
"name": "envafolimab",
"type": "Antibody",
"abbreviation": "",
"inn": "envafolimab",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13276,
"name": "enviomycin",
"type": "Natural product",
"abbreviation": "",
"inn": "enviomycin",
"approvalSource": "Japan (1975)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11874,
"name": "envonalkib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "envonalkib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6812,
"name": "enzalutamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "enzalutamide",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11371,
"name": "epalrestat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "epalrestat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11442,
"name": "epcoritamab",
"type": "Antibody",
"abbreviation": "",
"inn": "epcoritamab",
"approvalSource": "FDA & EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 556,
"name": "ephedrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "racephedrine",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7176,
"name": "epinastine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "epinastine",
"approvalSource": "FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2876,
"name": "eplerenone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eplerenone",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13606,
"name": "eplontersen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "eplontersen",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 588,
"name": "eprosartan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eprosartan",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6585,
"name": "eptifibatide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eptifibatide",
"approvalSource": "FDA (1998), EMA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10694,
"name": "eptinezumab",
"type": "Antibody",
"abbreviation": "",
"inn": "eptinezumab",
"approvalSource": "FDA (2020), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10805,
"name": "eravacycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eravacycline",
"approvalSource": "EMA & FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9039,
"name": "erdafitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "erdafitinib",
"approvalSource": "FDA (2019), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9250,
"name": "erenumab",
"type": "Antibody",
"abbreviation": "",
"inn": "erenumab",
"approvalSource": "FDA & EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 148,
"name": "ergometrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ergometrine",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 149,
"name": "ergotamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ergotamine",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6813,
"name": "eribulin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eribulin",
"approvalSource": "FDA (2010), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4920,
"name": "erlotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "erlotinib",
"approvalSource": "FDA (2004), EMA (2005)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10906,
"name": "ertapenem",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ertapenem",
"approvalSource": "FDA (2001), EMA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8376,
"name": "ertugliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ertugliflozin",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1456,
"name": "erythromycin",
"type": "Natural product",
"abbreviation": "EM-A",
"inn": "erythromycin",
"approvalSource": "FDA (no history prior to 1964)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4921,
"name": "erythropoietin",
"type": "Peptide",
"abbreviation": "",
"inn": "epoetin alfa",
"approvalSource": "FDA (no history prior to 1989 available)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 9894,
"name": "esaxerenone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "esaxerenone",
"approvalSource": "Japan (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7177,
"name": "escitalopram",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "escitalopram",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9420,
"name": "esflurbiprofen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "esflurbiprofen",
"approvalSource": "PMDA Japan (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9152,
"name": "esketamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "esketamine",
"approvalSource": "EMA & FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7350,
"name": "eslicarbazepine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eslicarbazepine",
"approvalSource": "FDA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7178,
"name": "esmolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "esmolol",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5488,
"name": "esomeprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "esomeprazole",
"approvalSource": "FDA (2001), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7550,
"name": "estazolam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "estazolam",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11591,
"name": "estetrol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "estetrol",
"approvalSource": "EMA & FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7655,
"name": "estradiol valerate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "estradiol valerate",
"approvalSource": "FDA (1954)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
1013
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9076,
"name": "estramustine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "estramustine",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2821,
"name": "estriol",
"type": "Metabolite",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2818,
"name": "estrone",
"type": "Metabolite",
"abbreviation": "",
"inn": "estrone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4749,
"name": "estrone-3-sulphate",
"type": "Metabolite",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7429,
"name": "eszopiclone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eszopiclone",
"approvalSource": "FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6789,
"name": "etanercept",
"type": "Peptide",
"abbreviation": "",
"inn": "etanercept",
"approvalSource": "FDA (1998), EMA (2000)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 8375,
"name": "etelcalcetide",
"type": "Peptide",
"abbreviation": "",
"inn": "etelcalcetide",
"approvalSource": "EMA (2016), FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7534,
"name": "eteplirsen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "eteplirsen",
"approvalSource": "FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7179,
"name": "ethacrynic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etacrynic acid",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12996,
"name": "ethambutol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ethambutol",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7180,
"name": "ethchlorvynol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ethchlorvynol",
"approvalSource": "FDA (prior to 1961)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7325,
"name": "ethinamate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ethinamate",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7071,
"name": "ethinylestradiol",
"type": "Metabolite",
"abbreviation": "",
"inn": "ethinylestradiol",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7087
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12954,
"name": "ethionamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ethionamide",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7181,
"name": "ethopropazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "profenamine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7182,
"name": "ethosuximide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ethosuximide",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7183,
"name": "ethotoin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ethotoin",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6814,
"name": "ethoxzolamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6948,
"name": "ethylestrenol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ethylestrenol",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7072,
"name": "ethynodiol diacetate",
"type": "Metabolite",
"abbreviation": "",
"inn": "etynodiol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7184,
"name": "etidronic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etidronic acid",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14324,
"name": "etilefrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etilefrine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7185,
"name": "etodolac",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etodolac",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5463,
"name": "etomidate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etomidate",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7590,
"name": "etonogestrel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etonogestrel",
"approvalSource": "FDA (2006), EMA (2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7065
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6815,
"name": "etoposide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etoposide",
"approvalSource": "FDA (1983)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2896,
"name": "etoricoxib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etoricoxib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9331,
"name": "etrasimod",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etrasimod",
"approvalSource": "FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12675,
"name": "etravirine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etravirine",
"approvalSource": "FDA & EMA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7599,
"name": "etretinate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etretinate",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14304,
"name": "etripamil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etripamil",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5889,
"name": "everolimus",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "everolimus",
"approvalSource": "FDA & EMA (2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8717,
"name": "evinacumab",
"type": "Antibody",
"abbreviation": "",
"inn": "evinacumab",
"approvalSource": "EMA & FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9042,
"name": "evocalcet",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "evocalcet",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7343,
"name": "evolocumab",
"type": "Antibody",
"abbreviation": "",
"inn": "evolocumab",
"approvalSource": "EMA & FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7073,
"name": "exemestane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "exemestane",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1135,
"name": "exendin-4",
"type": "Peptide",
"abbreviation": "",
"inn": "exenatide",
"approvalSource": "FDA (2005), EMA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6816,
"name": "ezetimibe",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ezetimibe",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8311,
"name": "fadrozole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fadrozole",
"approvalSource": "Japan only",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11629,
"name": "famciclovir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "famciclovir",
"approvalSource": "FDA (1994), UK (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7886,
"name": "famitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "famitinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7074,
"name": "famotidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "famotidine",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2416,
"name": "fampridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fampridine",
"approvalSource": "FDA (2010), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11420,
"name": "faricimab",
"type": "Antibody",
"abbreviation": "",
"inn": "faricimab",
"approvalSource": "EMA & FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5181,
"name": "fasudil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fasudil",
"approvalSource": "1995",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11139,
"name": "favipiravir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "favipiravir",
"approvalSource": "China and Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6817,
"name": "febuxostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "febuxostat",
"approvalSource": "EMA & FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5716,
"name": "fedratinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fedratinib",
"approvalSource": "FDA (2019), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5473,
"name": "felbamate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "felbamate",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4190,
"name": "felodipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "felodipine",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4613,
"name": "fenfluramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "dexfenfluramine,fenfluramine",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7186,
"name": "fenofibrate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fenofibrate",
"approvalSource": "FDA (1993), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2662
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 939,
"name": "fenoldopam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fenoldopam",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4820,
"name": "fenoprofen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fenoprofen",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 557,
"name": "fenoterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fenoterol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1626,
"name": "fentanyl",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fentanyl",
"approvalSource": "FDA (1968), EMA (2008)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7473,
"name": "fesoterodine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fesoterodine",
"approvalSource": "EMA (2007), FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4819,
"name": "fexofenadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fexofenadine",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10422,
"name": "fezolinetant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fezolinetant",
"approvalSource": "FDA, EMA & UK MHRA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10909,
"name": "fidaxomicin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fidaxomicin",
"approvalSource": "EMA & FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7913,
"name": "filgotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "filgotinib",
"approvalSource": "EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6968,
"name": "filgrastim",
"type": "Peptide",
"abbreviation": "",
"inn": "filgrastim",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10809,
"name": "finafloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "finafloxacin",
"approvalSource": "FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6818,
"name": "finasteride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "finasteride",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8678,
"name": "finerenone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "finerenone",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2407,
"name": "fingolimod",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fingolimod",
"approvalSource": "FDA (2010), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2924
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14401,
"name": "finotonlimab",
"type": "Antibody",
"abbreviation": "",
"inn": "finotonlimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10477,
"name": "firmonertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14399,
"name": "firsekibart",
"type": "Antibody",
"abbreviation": "",
"inn": "firsekibart",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13630,
"name": "fitusiran",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "fitusiran",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7187,
"name": "flavoxate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flavoxate",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2560,
"name": "flecainide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flecainide",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12476,
"name": "fleroxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fleroxacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8182,
"name": "flibanserin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flibanserin",
"approvalSource": "FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7769,
"name": "florbetaben",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "florbetaben (18F)",
"approvalSource": "EMA & FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": true,
"radioactive": true,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7344,
"name": "florbetapir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "florbetapir (18F)",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": true,
"radioactive": true,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9100,
"name": "flortaucipir (18F)",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flortaucipir (18F)",
"approvalSource": "FDA (2020), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": true,
"radioactive": true,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4801,
"name": "floxuridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "floxuridine",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
4789
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10910,
"name": "flucloxacillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flucloxacillin",
"approvalSource": "UK",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4802,
"name": "fludarabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fludarabine",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2873,
"name": "fludrocortisone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fludrocortisone",
"approvalSource": "FDA (1955), UK (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7606,
"name": "fludroxycortide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fludroxycortide",
"approvalSource": "FDA (1963)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2447,
"name": "flufenamic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flufenamic acid",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4192,
"name": "flumazenil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flumazenil",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9913,
"name": "flumbatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flumbatinib",
"approvalSource": "China (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13650,
"name": "flumequine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flumequine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7075,
"name": "flumethasone pivalate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flumetasone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12488,
"name": "flunarizine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flunarizine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7076,
"name": "flunisolide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flunisolide",
"approvalSource": "FDA (prior to1984)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4193,
"name": "flunitrazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flunitrazepam",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7077,
"name": "fluocinolone acetonide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluocinolone acetonide",
"approvalSource": "FDA (1963)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7078,
"name": "fluocinonide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluocinonide",
"approvalSource": "FDA (1971)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7079,
"name": "fluorometholone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluorometholone",
"approvalSource": "FDA (1972)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 203,
"name": "fluoxetine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluoxetine",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2861,
"name": "fluoxymesterone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluoxymesterone",
"approvalSource": "FDA (1956)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 948,
"name": "flupentixol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flupentixol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 204,
"name": "fluphenazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluphenazine",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7188,
"name": "flurazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flurazepam",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4194,
"name": "flurbiprofen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flurbiprofen",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12927,
"name": "flurithromycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flurithromycin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 85,
"name": "fluspirilene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluspirilene",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6943,
"name": "flutamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flutamide",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7342,
"name": "flutemetamol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "flutemetamol (18F)",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": true,
"radioactive": true,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6699,
"name": "fluticasone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluticasone",
"approvalSource": "FDA (1994), EMA (2008)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10892,
"name": "fluticasone furoate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluticasone furoate",
"approvalSource": "FDA (2007)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7080,
"name": "fluticasone propionate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluticasone",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2951,
"name": "fluvastatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluvastatin",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7189,
"name": "fluvoxamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fluvoxamine",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13763,
"name": "fluzoparib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4816,
"name": "folinic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1952)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11705,
"name": "fomepizole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fomepizole",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13533,
"name": "fomivirsen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "fomivirsen",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6819,
"name": "fondaparinux",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fondaparinux sodium",
"approvalSource": "FDA (2001), EMA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6896,
"name": "forasartan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "forasartan",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3465,
"name": "formoterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "formoterol",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12682,
"name": "fosamprenavir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fosamprenavir",
"approvalSource": "FDA (2003), EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
12681
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7623,
"name": "fosaprepitant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fosaprepitant",
"approvalSource": "FDA and EMA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
3490
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5497,
"name": "foscarnet",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "foscarnet sodium",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10813,
"name": "fosfomycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fosfomycin",
"approvalSource": "UK (1994), FDA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6456,
"name": "fosinopril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fosinopril",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6457
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6457,
"name": "fosinoprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fosinoprilat",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6456
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13174,
"name": "foslevodopa",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "foslevodopa",
"approvalSource": "EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
3639
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7190,
"name": "fosphenytoin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fosphenytoin",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2624
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7475,
"name": "fospropofol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fospropofol",
"approvalSource": "FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
5464
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14241,
"name": "fosrolapitant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fosrolapitant",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
5749
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7796,
"name": "fostamatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fostamatinib",
"approvalSource": "FDA (2018), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
5706
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11100,
"name": "fostemsavir",
"type": "Synthetic organic",
"abbreviation": "FTR",
"inn": "fostemsavir",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13951,
"name": "fotagliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13207,
"name": "fovinaciclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fovinaciclib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9208,
"name": "fremanezumab",
"type": "Antibody",
"abbreviation": "",
"inn": "fremanezumab",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7191,
"name": "frovatriptan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "frovatriptan",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9428,
"name": "fruquintinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fruquintinib",
"approvalSource": "China (2018), FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1157,
"name": "FSH",
"type": "Peptide",
"abbreviation": "",
"inn": "urofollitropin",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
3731,
3733
],
"species": "Human"
},
{
"ligandId": 1015,
"name": "fulvestrant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fulvestrant",
"approvalSource": "FDA (2002), EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12393,
"name": "fulzerasib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fulzerasib",
"approvalSource": "China NMPA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12367,
"name": "furagin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13898,
"name": "furaltadone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "furaltadone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12343,
"name": "furazolidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "furazolidone",
"approvalSource": "FDA (1958)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4839,
"name": "furosemide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "furosemide",
"approvalSource": "FDA (1966)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10815,
"name": "fusidic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "fusidic acid",
"approvalSource": "UK (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9786,
"name": "futibatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "futibatinib",
"approvalSource": "FDA (2022), EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5483,
"name": "gabapentin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gabapentin",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7560
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7560,
"name": "gabapentin enacarbil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gabapentin enacarbil",
"approvalSource": "FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
5483
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7863,
"name": "gabexate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gabexate",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6693,
"name": "galantamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "galantamine",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
13477
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8967,
"name": "galcanezumab",
"type": "Antibody",
"abbreviation": "",
"inn": "galcanezumab",
"approvalSource": "FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 356,
"name": "gallamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gallamine triethiodide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4711,
"name": "γ-hydroxybutyrate",
"type": "Metabolite",
"abbreviation": "GHB",
"inn": "",
"approvalSource": "FDA (2002), EMA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11942,
"name": "ganaxolone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ganaxolone",
"approvalSource": "FDA (2022), EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3877,
"name": "ganirelix",
"type": "Peptide",
"abbreviation": "",
"inn": "ganirelix",
"approvalSource": "FDA (1999), EMA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 13402,
"name": "garadacimab",
"type": "Antibody",
"abbreviation": "",
"inn": "garadacimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12402,
"name": "garenoxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "garenoxacin",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13767,
"name": "garsorasib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "garsorasib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10816,
"name": "gatifloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gatifloxacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4934,
"name": "G-CSF",
"type": "Peptide",
"abbreviation": "",
"inn": "lenograstim",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 9540,
"name": "gefapixant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gefapixant",
"approvalSource": "Japan (2022), EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4941,
"name": "gefitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gefitinib",
"approvalSource": "FDA (2003), EMA (2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4793,
"name": "gemcitabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gemcitabine",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3439,
"name": "gemfibrozil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gemfibrozil",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12406,
"name": "gemifloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gemifloxacin",
"approvalSource": "FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6775,
"name": "gemtuzumab ozogamicin",
"type": "Antibody",
"abbreviation": "",
"inn": "gemtuzumab ozogamicin",
"approvalSource": "FDA (2000), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2427,
"name": "gentamicin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gentamicin",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12930,
"name": "gepirone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gepirone",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10817,
"name": "gepotidacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gepotidacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11246,
"name": "gestodene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "UK (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8708,
"name": "gilteritinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "gilteritinib",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7490,
"name": "givinostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "givinostat",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13614,
"name": "givosiran",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "givosiran",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8201,
"name": "glasdegib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "glasdegib",
"approvalSource": "FDA (2018), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11267,
"name": "glecaprevir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "glecaprevir",
"approvalSource": "EMA & FDA (2017)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14394,
"name": "glecirasib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "glecirasib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2414,
"name": "glibenclamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "glibenclamide",
"approvalSource": "FDA (as glyburide, 1984), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6820,
"name": "glimepiride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "glimepiride",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6821,
"name": "glipizide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "glipizide",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12758,
"name": "glofitamab",
"type": "Antibody",
"abbreviation": "",
"inn": "glofitamab",
"approvalSource": "FDA & EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1136,
"name": "glucagon",
"type": "Peptide",
"abbreviation": "",
"inn": "glucagon",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human, Mouse, Rat"
},
{
"ligandId": 7450,
"name": "glucarpidase",
"type": "Peptide",
"abbreviation": "",
"inn": "glucarpidase",
"approvalSource": "FDA (2012), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7192,
"name": "glutethimide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "glutethimide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7459,
"name": "glycopyrrolate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "glycopyrronium bromide",
"approvalSource": "FDA (1961), EMA (2012)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10744,
"name": "golidocitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "golidocitinib",
"approvalSource": "China NMPA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6776,
"name": "golimumab",
"type": "Antibody",
"abbreviation": "",
"inn": "golimumab",
"approvalSource": "FDA (2009), EMA (2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13605,
"name": "golodirsen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "golodirsen",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3879,
"name": "goserelin",
"type": "Peptide",
"abbreviation": "",
"inn": "goserelin",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 2300,
"name": "granisetron",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "granisetron",
"approvalSource": "FDA (1993), EMA (2012)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11573,
"name": "grazoprevir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "grazoprevir",
"approvalSource": "FDA (2016), UK (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10818,
"name": "grepafloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "grepafloxacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4943,
"name": "growth hormone 1",
"type": "Peptide",
"abbreviation": "",
"inn": "somatropin",
"approvalSource": "FDA (1976), EMA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 7617,
"name": "guaifenesin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "guaifenesin",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5443,
"name": "guanabenz",
"type": "Synthetic organic",
"abbreviation": "GBZ",
"inn": "guanabenz",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7193,
"name": "guanadrel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "guanadrel",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7194,
"name": "guanethidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "guanethidine",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 522,
"name": "guanfacine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "guanfacine",
"approvalSource": "FDA (1986), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4783,
"name": "guanidine",
"type": "Metabolite",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1939)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7998,
"name": "guselkumab",
"type": "Antibody",
"abbreviation": "",
"inn": "guselkumab",
"approvalSource": "EMA & FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7195,
"name": "halazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "halazepam",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10019,
"name": "halofantrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "halofantrine",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 86,
"name": "haloperidol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "haloperidol",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2401,
"name": "halothane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "halothane",
"approvalSource": "FDA (1958)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13762,
"name": "henagliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4214,
"name": "heparin",
"type": "Metabolite",
"abbreviation": "",
"inn": "heparin sodium",
"approvalSource": "FDA (1939)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12263,
"name": "hetacillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hetacillin",
"approvalSource": "FDA (1971)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10896
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10657,
"name": "hetrombopag",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11069,
"name": "hexachlorophene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hexachlorophene",
"approvalSource": "FDA (1949)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7196,
"name": "hexylcaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hexylcaine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3884,
"name": "histrelin",
"type": "Peptide",
"abbreviation": "",
"inn": "histrelin",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 13727,
"name": "huperzine A",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7326,
"name": "hydralazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hydralazine",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4836,
"name": "hydrochlorothiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hydrochlorothiazide",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7081,
"name": "hydrocodone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hydrocodone",
"approvalSource": "FDA (no approval history prior to 2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7197,
"name": "hydroflumethiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hydroflumethiazide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7082,
"name": "hydromorphone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hydromorphone",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7198,
"name": "hydroxychloroquine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hydroxychloroquine",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6822,
"name": "hydroxyurea",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hydroxycarbamide",
"approvalSource": "FDA (1967), EMA (2007)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7199,
"name": "hydroxyzine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "hydroxyzine",
"approvalSource": "FDA (1956)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10208,
"name": "ibalizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "ibalizumab",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3059,
"name": "ibandronic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ibandronic acid",
"approvalSource": "EMA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6777,
"name": "ibritumomab tiuxetan",
"type": "Antibody",
"abbreviation": "",
"inn": "ibritumomab tiuxetan",
"approvalSource": "FDA (2002), EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6912,
"name": "ibrutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ibrutinib",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7399,
"name": "ibudilast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ibudilast",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2713,
"name": "ibuprofen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ibuprofen",
"approvalSource": "FDA (1974), EMA (2004)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7200,
"name": "ibutilide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ibutilide",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 667,
"name": "icatibant",
"type": "Peptide",
"abbreviation": "",
"inn": "icatibant",
"approvalSource": "EMA (2008), FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7441,
"name": "icosapent",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "icosapent",
"approvalSource": "FDA (2012), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7641,
"name": "icotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "China (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7083,
"name": "idarubicin",
"type": "Natural product",
"abbreviation": "",
"inn": "idarubicin",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8298,
"name": "idarucizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "idarucizumab",
"approvalSource": "FDA and EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6741,
"name": "idelalisib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "idelalisib",
"approvalSource": "FDA & EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4960,
"name": "IFN-α2",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 8338,
"name": "IFN-α2b (recombinant human)",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 8339,
"name": "IFN-β1a (recombinant human)",
"type": "Peptide",
"abbreviation": "",
"inn": "interferon beta",
"approvalSource": "FDA (1996), EMA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 8340,
"name": "IFN-β1b (recombinant human)",
"type": "Peptide",
"abbreviation": "",
"inn": "interferon beta",
"approvalSource": "FDA (1993), EMA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 4968,
"name": "IFN-γ",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 8341,
"name": "IFN-γ1b (human recombinant)",
"type": "Peptide",
"abbreviation": "",
"inn": "interferon gamma",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7201,
"name": "ifosfamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ifosfamide",
"approvalSource": "FDA (1988)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14249,
"name": "ifupinostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ifupinostat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9736,
"name": "iguratimod",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "iguratimod",
"approvalSource": "China (2011), Japan (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4985,
"name": "IL-2",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 10512,
"name": "ilaprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ilaprazole",
"approvalSource": "South Korea, China",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 87,
"name": "iloperidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "iloperidone",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
14405
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1895,
"name": "iloprost",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "iloprost",
"approvalSource": "EMA (2003), FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5687,
"name": "imatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "imatinib",
"approvalSource": "FDA & EMA (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11328,
"name": "imdevimab",
"type": "Antibody",
"abbreviation": "",
"inn": "imdevimab",
"approvalSource": "Japan, EMA and UK MHRA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13625,
"name": "imetelstat",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "imetelstat",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6377,
"name": "imidapril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "imidapril",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6378
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6378,
"name": "imidaprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "imidaprilat",
"approvalSource": "FDA",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6377
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10821,
"name": "imipenem",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "imipenem",
"approvalSource": "FDA (1985), UK (1988)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 357,
"name": "imipramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "imipramine",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5003,
"name": "imiquimod",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "imiquimod",
"approvalSource": "FDA (1997), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12896,
"name": "imlunestrant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "imlunestrant",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7202,
"name": "inamrinone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "amrinone",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9636,
"name": "inavolisib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "inavolisib",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13624,
"name": "inclisiran",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "inclisiran",
"approvalSource": "EMA (2020), FDA & UK MHRA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7455,
"name": "indacaterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "indacaterol",
"approvalSource": "EMA (2009), FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7203,
"name": "indapamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "indapamide",
"approvalSource": "FDA (1983)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12684,
"name": "indinavir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "indinavir",
"approvalSource": "FDA & EMA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1909,
"name": "indomethacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "indometacin",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 501,
"name": "indoramin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "indoramin",
"approvalSource": "UK (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7992,
"name": "inebilizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "inebilizumab",
"approvalSource": "FDA (2020), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7877,
"name": "infigratinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "infigratinib",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5004,
"name": "infliximab",
"type": "Antibody",
"abbreviation": "",
"inn": "infliximab",
"approvalSource": "FDA (1998), EMA (1999)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7443,
"name": "ingenol mebutate",
"type": "Natural product",
"abbreviation": "",
"inn": "ingenol mebutate",
"approvalSource": "FDA & EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13543,
"name": "inotersen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "inotersen",
"approvalSource": "EMA & FDA (2018), UK MHRA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8266,
"name": "inotuzumab ozogamicin",
"type": "Antibody",
"abbreviation": "",
"inn": "inotuzumab ozogamicin",
"approvalSource": "EMA & FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5012,
"name": "insulin",
"type": "Peptide",
"abbreviation": "",
"inn": "insulin human",
"approvalSource": "FDA (1982), EMA (1997)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
5013,
5014
],
"species": "Human"
},
{
"ligandId": 7572,
"name": "insulin glargine",
"type": "Peptide",
"abbreviation": "",
"inn": "insulin glargine",
"approvalSource": "FDA and EMA (2000)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 4971,
"name": "insulin-like growth factor 1",
"type": "Peptide",
"abbreviation": "IGF-1",
"inn": "mecasermin",
"approvalSource": "FDA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 7400,
"name": "iodipamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "adipiodone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": true,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7653,
"name": "ioflupane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ioflupane (123I)",
"approvalSource": "EMA (2000), FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13792,
"name": "iparomlimab",
"type": "Antibody",
"abbreviation": "",
"inn": "iparomlimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6888,
"name": "ipilimumab",
"type": "Antibody",
"abbreviation": "",
"inn": "ipilimumab",
"approvalSource": "FDA and EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9394,
"name": "ipragliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ipragliflozin",
"approvalSource": "Japan (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 325,
"name": "ipratropium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ipratropium bromide",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10710,
"name": "iptacopan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "iptacopan",
"approvalSource": "FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 589,
"name": "irbesartan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "irbesartan",
"approvalSource": "EMA & FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1214,
"name": "(R)-cetirizine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levocetirizine",
"approvalSource": "FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6823,
"name": "irinotecan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "irinotecan",
"approvalSource": "FDA (1996), EMA (2016)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6925
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11877,
"name": "iruplinalkib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "iruplinalkib",
"approvalSource": "China (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8719,
"name": "isatuximab",
"type": "Antibody",
"abbreviation": "",
"inn": "isatuximab",
"approvalSource": "EMA & FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12136,
"name": "isepamicin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isepamicin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7204,
"name": "isocarboxazid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isocarboxazid",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7205,
"name": "isoetarine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isoetarine",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2505,
"name": "isoflurane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isoflurane",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12761,
"name": "isoniazid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isoniazid",
"approvalSource": "FDA (1952), UK",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 536,
"name": "isoprenaline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isoprenaline",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7051,
"name": "isosorbide dinitrate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isosorbide dinitrate",
"approvalSource": "FDA (no history prior to 1968)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7052,
"name": "isosorbide mononitrate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isosorbide mononitrate",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7600,
"name": "isotretinoin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isotretinoin",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4488,
"name": "isradipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "isradipine",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5608,
"name": "istradefylline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "istradefylline",
"approvalSource": "Japan (2013), FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9421,
"name": "itolizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "itolizumab",
"approvalSource": "DCGI (India; 2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11426,
"name": "itraconazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "itraconazole",
"approvalSource": "FDA (1992), UK (1989)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2357,
"name": "ivabradine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ivabradine",
"approvalSource": "EMA (2005), FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4342,
"name": "ivacaftor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ivacaftor",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11878,
"name": "ivarmacitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ivarmacitinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2373,
"name": "ivermectin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ivermectin",
"approvalSource": "FDA (1996), UK (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13396,
"name": "ivonescimab",
"type": "Antibody",
"abbreviation": "",
"inn": "ivonescimab",
"approvalSource": "China (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9217,
"name": "ivosidenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ivosidenib",
"approvalSource": "FDA (2018), EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6824,
"name": "ixabepilone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ixabepilone",
"approvalSource": "FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8450,
"name": "ixazomib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ixazomib",
"approvalSource": "FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7541,
"name": "ixekizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "ixekizumab",
"approvalSource": "FDA & EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14393,
"name": "jaktinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13950,
"name": "janagliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12924,
"name": "josamycin",
"type": "Natural product",
"abbreviation": "",
"inn": "josamycin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12132,
"name": "kanamycin",
"type": "Natural product",
"abbreviation": "",
"inn": "kanamycin",
"approvalSource": "FDA (1973)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4233,
"name": "ketamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ketamine",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 88,
"name": "ketanserin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ketanserin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2568,
"name": "ketoconazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ketoconazole",
"approvalSource": "FDA (1981), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4795,
"name": "ketoprofen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ketoprofen",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6661,
"name": "ketorolac",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ketorolac",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7206,
"name": "ketotifen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ketotifen",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12653,
"name": "keverprazan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "China (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7207,
"name": "labetalol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "labetalol",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11740,
"name": "lacidipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lacidipine",
"approvalSource": "UK (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7472,
"name": "lacosamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lacosamide",
"approvalSource": "EMA and FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5217,
"name": "L-α-methyldopa",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methyldopa",
"approvalSource": "FDA (1962)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12673,
"name": "lamivudine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lamivudine",
"approvalSource": "FDA (1995), EMA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2622,
"name": "lamotrigine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lamotrigine",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9094,
"name": "lanadelumab",
"type": "Antibody",
"abbreviation": "",
"inn": "lanadelumab",
"approvalSource": "EMA & FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13192,
"name": "landiolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "landiolol",
"approvalSource": "Japan and some European countries, FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2031,
"name": "lanreotide",
"type": "Peptide",
"abbreviation": "",
"inn": "lanreotide",
"approvalSource": "UK (2001), FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7208,
"name": "lansoprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lansoprazole",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5692,
"name": "lapatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lapatinib",
"approvalSource": "FDA (2007), EMA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8909,
"name": "larotrectinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "larotrectinib",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3928,
"name": "lasmiditan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lasmiditan",
"approvalSource": "FDA (2019), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12031,
"name": "latamoxef",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "latamoxef",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9635,
"name": "latanoprostene bunod",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "latanoprostene bunod",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1960,
"name": "latanoprost (free acid form)",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
1961
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1961,
"name": "latanoprost (isopropyl ester)",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "latanoprost",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
1960
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10136,
"name": "lazertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lazertinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9488,
"name": "L-cycloserine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "cycloserine",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7684,
"name": "lebrikizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "lebrikizumab",
"approvalSource": "EMA (2023), FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12202,
"name": "lecanemab",
"type": "Antibody",
"abbreviation": "",
"inn": "lecanemab",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11271,
"name": "ledipasvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ledipasvir",
"approvalSource": "EMA & FDA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10824,
"name": "lefamulin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lefamulin",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6825,
"name": "leflunomide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "leflunomide",
"approvalSource": "FDA (1998), EMA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6844
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9302,
"name": "lemborexant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lemborexant",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11446,
"name": "lenacapavir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lenacapavir",
"approvalSource": "EMA & FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7331,
"name": "lenalidomide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lenalidomide",
"approvalSource": "FDA (2005), EMA (2007)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9424,
"name": "leniolisib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "leniolisib",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7426,
"name": "lenvatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lenvatinib",
"approvalSource": "FDA & EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6469,
"name": "lepirudin",
"type": "Peptide",
"abbreviation": "",
"inn": "lepirudin",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10313,
"name": "lerociclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lerociclib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14319,
"name": "lerodalcibep",
"type": "Peptide",
"abbreviation": "",
"inn": "lerodalcibep",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7673,
"name": "lesinurad",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lesinurad",
"approvalSource": "FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5209,
"name": "letrozole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "letrozole",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9274,
"name": "leucomethylthioninium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1175,
"name": "leuprolide",
"type": "Peptide",
"abbreviation": "",
"inn": "leuprorelin",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7209,
"name": "levallorphan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levallorphan",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7210,
"name": "levamisole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levamisole",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": true,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6826,
"name": "levetiracetam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "etiracetam,levetiracetam",
"approvalSource": "FDA (1999), EMA (2000)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8035,
"name": "levobetaxolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levobetaxolol",
"approvalSource": "FDA (2000) no prior history available",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7211,
"name": "levobupivacaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levobupivacaine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1586,
"name": "levocabastine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levocabastine",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3639,
"name": "levodopa",
"type": "Metabolite",
"abbreviation": "",
"inn": "levodopa",
"approvalSource": "FDA (1993), EMA (2003)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
13174
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10911,
"name": "levofloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levofloxacin",
"approvalSource": "FDA (1996), EMA (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11829,
"name": "levoketoconazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levoketoconazole",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7603,
"name": "levomepromazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levomepromazine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7212,
"name": "levomethadyl acetate",
"type": "Synthetic organic",
"abbreviation": "LAAM",
"inn": "levacetylmethadol",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7435,
"name": "levomilnacipran",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levomilnacipran",
"approvalSource": "FDA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2881,
"name": "levonorgestrel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levonorgestrel,norgestrel",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7595,
"name": "levorphanol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levorphanol",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9816,
"name": "levosalbutamol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levosalbutamol",
"approvalSource": "FDA (prior to 1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1159,
"name": "LH",
"type": "Peptide",
"abbreviation": "",
"inn": "lutropin alfa",
"approvalSource": "FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
3732,
3731
],
"species": "Human"
},
{
"ligandId": 2623,
"name": "lidocaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lidocaine",
"approvalSource": "FDA (1948)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7533,
"name": "lifitegrast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lifitegrast",
"approvalSource": "FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14195,
"name": "limertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5017,
"name": "linaclotide",
"type": "Peptide",
"abbreviation": "",
"inn": "linaclotide",
"approvalSource": "FDA and EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6318,
"name": "linagliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "linagliptin",
"approvalSource": "EMA & FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13761,
"name": "linaprazan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "linaprazan",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10941,
"name": "lincomycin",
"type": "Natural product",
"abbreviation": "",
"inn": "lincomycin",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10827,
"name": "linezolid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "linezolid",
"approvalSource": "FDA (2000), UK (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13305,
"name": "linvoseltamab",
"type": "Antibody",
"abbreviation": "",
"inn": "linvoseltamab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12283,
"name": "linzagolix",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "linzagolix",
"approvalSource": "EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1133,
"name": "liraglutide",
"type": "Peptide",
"abbreviation": "",
"inn": "liraglutide",
"approvalSource": "EMA (2009), FDA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 13108,
"name": "lisaftoclax",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lisaftoclax",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7213,
"name": "lisdexamfetamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lisdexamfetamine",
"approvalSource": "FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2147
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6360,
"name": "lisinopril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lisinopril",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5212,
"name": "Li+",
"type": "Inorganic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 43,
"name": "lisuride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lisuride",
"approvalSource": "EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7387,
"name": "lixisenatide",
"type": "Peptide",
"abbreviation": "",
"inn": "lixisenatide",
"approvalSource": "EMA (2013), FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 9743,
"name": "lodoxamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lodoxamide",
"approvalSource": "UK (1991), FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7551,
"name": "lofepramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lofepramine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9868,
"name": "lofexidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lofexidine",
"approvalSource": "UK (1990), FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12407,
"name": "lomefloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lomefloxacin",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7439,
"name": "lomitapide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lomitapide",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7214,
"name": "lomustine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lomustine",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8024,
"name": "lonafarnib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lonafarnib",
"approvalSource": "FDA (2020), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11521,
"name": "loncastuximab tesirine",
"type": "Antibody",
"abbreviation": "",
"inn": "loncastuximab tesirine",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7215,
"name": "loperamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "loperamide",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11504,
"name": "lopinavir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lopinavir",
"approvalSource": "FDA (2000), EMA (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
9502
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12247,
"name": "loracarbef",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "loracarbef",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7216,
"name": "loratadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "loratadine",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5884,
"name": "lorazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lorazepam",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2941,
"name": "lorcaserin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lorcaserin",
"approvalSource": "FDA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7476,
"name": "lorlatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lorlatinib",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7553,
"name": "lormetazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lormetazepam",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 590,
"name": "losartan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "losartan",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7085,
"name": "loteprednol etabonate",
"type": "Metabolite",
"abbreviation": "",
"inn": "loteprednol",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2739,
"name": "lovastatin",
"type": "Natural product",
"abbreviation": "",
"inn": "lovastatin",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 205,
"name": "loxapine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "loxapine",
"approvalSource": "FDA (1975), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4242,
"name": "lubiprostone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lubiprostone",
"approvalSource": "FDA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7366,
"name": "luliconazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "luliconazole",
"approvalSource": "FDA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7481,
"name": "lumacaftor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lumacaftor",
"approvalSource": "EMA & FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13613,
"name": "lumasiran",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "lumasiran",
"approvalSource": "EMA, FDA & UK MHRA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9099,
"name": "lumateperone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lumateperone",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9969,
"name": "lumefantrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lumefantrine",
"approvalSource": "FDA (2009) in combination with artemether",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2897,
"name": "lumiracoxib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lumiracoxib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7461,
"name": "lurasidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lurasidone",
"approvalSource": "FDA (2010), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10681,
"name": "lurbinectedin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lurbinectedin",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10538,
"name": "luspatercept",
"type": "Peptide",
"abbreviation": "",
"inn": "luspatercept",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10032,
"name": "lusutrombopag",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lusutrombopag",
"approvalSource": "Japan (2015), FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13495,
"name": "luvometinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "luvometinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10912,
"name": "lymecycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "lymecycline",
"approvalSource": "UK (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9745,
"name": "macimorelin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "macimorelin",
"approvalSource": "FDA (2017), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7352,
"name": "macitentan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "macitentan",
"approvalSource": "FDA and EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12697,
"name": "mafenide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mafenide",
"approvalSource": "FDA (1969)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11739,
"name": "manidipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "manidipine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2402,
"name": "maprotiline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "maprotiline",
"approvalSource": "FDA (1980)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11708,
"name": "maralixibat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "maralixibat chloride",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 806,
"name": "maraviroc",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "maraviroc",
"approvalSource": "EMA and FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8686,
"name": "margetuximab",
"type": "Antibody",
"abbreviation": "",
"inn": "margetuximab",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12049,
"name": "maribavir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "maribavir",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13403,
"name": "marstacimab",
"type": "Antibody",
"abbreviation": "",
"inn": "marstacimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11265,
"name": "mavacamten",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mavacamten",
"approvalSource": "FDA (2022), EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8580,
"name": "mavorixafor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mavorixafor",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13924,
"name": "mazdutide",
"type": "Peptide",
"abbreviation": "",
"inn": "mazdutide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 4797,
"name": "mazindol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mazindol",
"approvalSource": "FDA (1973)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13427,
"name": "mebendazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mebendazole",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9011,
"name": "mebeverine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mebeverine",
"approvalSource": "UK (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3990,
"name": "mecamylamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mecamylamine",
"approvalSource": "FDA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7218,
"name": "mechlorethamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "chlormethine",
"approvalSource": "FDA (1949), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12813,
"name": "mecillinam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mecillinam",
"approvalSource": "FDA (1984), UK (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
10922
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2757,
"name": "meclizine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "meclozine",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13540,
"name": "meclocycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "meclocycline",
"approvalSource": "FDA",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7219,
"name": "meclofenamic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "meclofenamic acid",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2879,
"name": "medroxyprogesterone",
"type": "Synthetic organic",
"abbreviation": "MPA",
"inn": "medroxyprogesterone",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7086,
"name": "medrysone",
"type": "Metabolite",
"abbreviation": "",
"inn": "medrysone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2593,
"name": "mefenamic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mefenamic acid",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4252,
"name": "mefloquine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mefloquine",
"approvalSource": "FDA (1989), UK (1989)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9128,
"name": "megestrol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "megestrol",
"approvalSource": "FDA (1971)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 224,
"name": "melatonin",
"type": "Metabolite",
"abbreviation": "MLT",
"inn": "",
"approvalSource": "EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7220,
"name": "meloxicam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "meloxicam",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7620,
"name": "melphalan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "melphalan",
"approvalSource": "FDA (1964), EMA (2020)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
11605
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11605,
"name": "melphalan flufenamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "melphalan flufenamide",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7620
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4253,
"name": "memantine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "memantine",
"approvalSource": "EMA (2002), FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2430,
"name": "(-)-menthol",
"type": "Natural product",
"abbreviation": "",
"inn": "levomenthol,racementhol",
"approvalSource": "FDA (2008), no prior history available",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10470,
"name": "mepenzolic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mepenzolate bromide",
"approvalSource": "FDA (1956)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7222,
"name": "mephentermine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mephentermine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7223,
"name": "mephenytoin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mephenytoin",
"approvalSource": "FDA (1946)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7224,
"name": "mepivacaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mepivacaine",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7685,
"name": "mepolizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "mepolizumab",
"approvalSource": "EMA & FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7225,
"name": "meprobamate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "meprobamate",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7610
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9083,
"name": "meptazinol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "meptazinol",
"approvalSource": "UK (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1227,
"name": "mepyramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mepyramine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6827,
"name": "mequinol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mequinol",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7440,
"name": "mercaptamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mercaptamine",
"approvalSource": "FDA (1994), EMA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7226,
"name": "mercaptopurine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mercaptopurine",
"approvalSource": "FDA (1953), EMA (2012)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7120
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10829,
"name": "meropenem",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "meropenem",
"approvalSource": "FDA (1996), EMA (2018)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2700,
"name": "mesalazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mesalazine",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
11569,
11578
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7227,
"name": "mesoridazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mesoridazine",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7087,
"name": "mestranol",
"type": "Metabolite",
"abbreviation": "",
"inn": "mestranol",
"approvalSource": "FDA (1962)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7071
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7228,
"name": "mesuximide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mesuximide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13618,
"name": "metacycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metacycline",
"approvalSource": "France",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7229,
"name": "metaraminol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metaraminol",
"approvalSource": "FDA (1954)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7609,
"name": "metaxalone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metaxalone",
"approvalSource": "FDA (1962)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4779,
"name": "metformin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metformin",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7438,
"name": "methacholine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methacholine chloride",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5458,
"name": "methadone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methadone",
"approvalSource": "FDA (1947, prior history not available)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4803,
"name": "methamphetamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metamfetamine",
"approvalSource": "FDA (1943)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7230,
"name": "metharbital",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metharbital",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6828,
"name": "methazolamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methazolamide",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7231,
"name": "methdilazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methdilazine",
"approvalSource": "FDA (date unknown)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10913,
"name": "methenamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methenamine",
"approvalSource": "FDA (1967), UK (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12264,
"name": "methicillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "meticillin",
"approvalSource": "FDA (1971)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6649,
"name": "methimazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7232,
"name": "methixene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pimethixene",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6829,
"name": "methocarbamol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methocarbamol",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7233,
"name": "methohexital",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methohexital",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4815,
"name": "methotrexate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methotrexate",
"approvalSource": "FDA (1953), EMA (2016)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 483,
"name": "methoxamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methoxamine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12457,
"name": "methoxsalen",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1954)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7234,
"name": "methoxyflurane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methoxyflurane",
"approvalSource": "FDA (date unknown)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7235,
"name": "methyclothiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methyclothiazide",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 150,
"name": "methylergonovine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methylergometrine",
"approvalSource": "FDA (1946)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7563,
"name": "methylnaltrexone",
"type": "Synthetic organic",
"abbreviation": "MNTX",
"inn": "methylnaltrexone bromide",
"approvalSource": "EMA & FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7236,
"name": "methylphenidate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methylphenidate",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7088,
"name": "methylprednisolone",
"type": "Metabolite",
"abbreviation": "",
"inn": "methylprednisolone",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5094,
"name": "methyltyrosine",
"type": "Metabolite",
"abbreviation": "",
"inn": "racemetirosine",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7238,
"name": "methyprylon",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methyprylon",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 134,
"name": "methysergide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "methysergide",
"approvalSource": "FDA (1962)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7239,
"name": "metipranolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metipranolol",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 241,
"name": "metoclopramide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metoclopramide",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4838,
"name": "metolazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metolazone",
"approvalSource": "FDA (1973)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11140,
"name": "metopimazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metopimazine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 553,
"name": "metoprolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metoprolol",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7333,
"name": "metreleptin",
"type": "Peptide",
"abbreviation": "",
"inn": "metreleptin",
"approvalSource": "FDA (2014), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10914,
"name": "metronidazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metronidazole",
"approvalSource": "FDA (1963)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5224,
"name": "metyrapone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "metyrapone",
"approvalSource": "FDA (1961)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2629,
"name": "mexiletine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mexiletine",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12272,
"name": "mezlocillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mezlocillin",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 135,
"name": "mianserin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mianserin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2522,
"name": "mibefradil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mibefradil",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2449,
"name": "miconazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "miconazole",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12162,
"name": "micronomicin",
"type": "Natural product",
"abbreviation": "",
"inn": "micronomicin",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3342,
"name": "midazolam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "midazolam",
"approvalSource": "FDA (2000), EMA (2011)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13158,
"name": "midecamycin",
"type": "Natural product",
"abbreviation": "",
"inn": "midecamycin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7240,
"name": "midodrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "midodrine",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5702,
"name": "midostaurin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "midostaurin",
"approvalSource": "FDA & EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8274,
"name": "mifamurtide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mifamurtide",
"approvalSource": "EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12380,
"name": "mifanertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mifanertinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2805,
"name": "mifepristone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mifepristone",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10200,
"name": "migalastat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "migalastat",
"approvalSource": "EMA (2016), FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4842,
"name": "miglitol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "miglitol",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4841,
"name": "miglustat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "miglustat",
"approvalSource": "EMA (2002), FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7436,
"name": "milnacipran",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "milnacipran",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5225,
"name": "milrinone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "milrinone",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14405,
"name": "milsaperidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "milsaperidone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
87
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11355,
"name": "miltefosine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "miltefosine",
"approvalSource": "FDA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11993,
"name": "mindeudesivir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mindeudesivir",
"approvalSource": "China NMPA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10831,
"name": "minocycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "minocycline",
"approvalSource": "FDA (1971), UK (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4254,
"name": "minoxidil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "minoxidil",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7364,
"name": "mipomersen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "mipomersen",
"approvalSource": "FDA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7445,
"name": "mirabegron",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mirabegron",
"approvalSource": "FDA and EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7935,
"name": "mirdametinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mirdametinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9846,
"name": "mirikizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "mirikizumab",
"approvalSource": "Japan, EMA and FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11738,
"name": "mirodenafil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mirodenafil",
"approvalSource": "Korea (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8303,
"name": "mirogabalin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mirogabalin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7241,
"name": "mirtazapine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mirtazapine",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12250,
"name": "mirvetuximab soravtansine",
"type": "Antibody",
"abbreviation": "",
"inn": "mirvetuximab soravtansine",
"approvalSource": "FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1936,
"name": "misoprostol (methyl ester)",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "misoprostol",
"approvalSource": "FDA (1988)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
1935
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10473,
"name": "mitapivat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mitapivat",
"approvalSource": "EMA & FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8394,
"name": "mithramycin",
"type": "Natural product",
"abbreviation": "",
"inn": "plicamycin",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7089,
"name": "mitomycin C",
"type": "Natural product",
"abbreviation": "",
"inn": "mitomycin",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6957,
"name": "mitotane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mitotane",
"approvalSource": "FDA (1970), EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7242,
"name": "mitoxantrone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mitoxantrone",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7243,
"name": "mivacurium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mivacurium chloride",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10102,
"name": "mizolastine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mizolastine",
"approvalSource": "UK (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10468,
"name": "mobocertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mobocertinib",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7428,
"name": "moclobemide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "moclobemide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7555,
"name": "modafinil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "modafinil",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6571,
"name": "moexipril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "moexipril",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6572
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6572,
"name": "moexiprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "moexiprilat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6571
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6477,
"name": "mogamulizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "mogamulizumab",
"approvalSource": "PMDA (Japan, 2012), EMA & FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 207,
"name": "molindone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "molindone",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10737,
"name": "molnupiravir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "UK (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10735
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7791,
"name": "momelotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "momelotinib",
"approvalSource": "FDA (2023), Japan PMDA & EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9029,
"name": "mometasone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mometasone",
"approvalSource": "1987 (FDA)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6830,
"name": "monobenzone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "monobenzone",
"approvalSource": "FDA (1952)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3340,
"name": "montelukast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "montelukast",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7244,
"name": "moracizine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "moracizine",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1627,
"name": "morphine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1984), prior history not available",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
9082
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 242,
"name": "mosapride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mosapride",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12298,
"name": "mosunetuzumab",
"type": "Antibody",
"abbreviation": "",
"inn": "mosunetuzumab",
"approvalSource": "EMA & FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10679,
"name": "motixafortide",
"type": "Peptide",
"abbreviation": "",
"inn": "motixafortide",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7675,
"name": "moxetumomab pasudotox",
"type": "Antibody",
"abbreviation": "",
"inn": "moxetumomab pasudotox",
"approvalSource": "FDA (2018), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10915,
"name": "moxifloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "moxifloxacin",
"approvalSource": "FDA (1999), UK (2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12306,
"name": "moxisylyte",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "moxisylyte",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12574,
"name": "moxonidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "moxonidine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14395,
"name": "mufemilast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mufemilast",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10916,
"name": "mupirocin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "mupirocin",
"approvalSource": "FDA (1987), UK (1998)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6889,
"name": "muromonab-CD3",
"type": "Antibody",
"abbreviation": "",
"inn": "muromonab-CD3",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6831,
"name": "mycophenolate mofetil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1995), EMA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6832
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6832,
"name": "mycophenolic acid",
"type": "Natural product",
"abbreviation": "",
"inn": "mycophenolic acid",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6831
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9071,
"name": "nabilone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nabilone",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7245,
"name": "nabumetone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nabumetone",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12919,
"name": "nadifloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nadifloxacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 554,
"name": "nadolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nadolol",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4262,
"name": "nafamostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nafamostat",
"approvalSource": "Japan only",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3902,
"name": "nafarelin",
"type": "Peptide",
"abbreviation": "",
"inn": "nafarelin",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10942,
"name": "nafcillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nafcillin",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4507,
"name": "NaHCO3",
"type": "Inorganic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1986, no prior history available)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1663,
"name": "nalbuphine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nalbuphine",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9150,
"name": "naldemedine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "naldemedine",
"approvalSource": "FDA (2017), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1651,
"name": "nalfurafine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nalfurafine",
"approvalSource": "Japan (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12773,
"name": "nalidixic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nalidixic acid",
"approvalSource": "FDA (1964), EMA",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1628,
"name": "nalmefene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nalmefene",
"approvalSource": "EMA (2013), FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1629,
"name": "nalorphine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nalorphine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7539,
"name": "naloxegol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "naloxegol",
"approvalSource": "EMA & FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1638,
"name": "naloxone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "naloxone",
"approvalSource": "FDA (1971), EMA (2017)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1639,
"name": "naltrexone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "naltrexone",
"approvalSource": "FDA (1998), UK (2011)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6949,
"name": "nandrolone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nandrolone",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5509,
"name": "naphazoline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "naphazoline",
"approvalSource": "FDA (1971, prior history not available)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5230,
"name": "naproxen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "naproxen",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
9551
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 45,
"name": "naratriptan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "naratriptan",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11572,
"name": "narlaprevir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "narlaprevir",
"approvalSource": "Russia (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13084,
"name": "narlumosbart",
"type": "Antibody",
"abbreviation": "",
"inn": "narlumosbart",
"approvalSource": "China (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14317,
"name": "narsoplimab",
"type": "Antibody",
"abbreviation": "",
"inn": "narsoplimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6591,
"name": "natalizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "natalizumab",
"approvalSource": "FDA (2004), EMA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6833,
"name": "nateglinide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nateglinide",
"approvalSource": "FDA (2000), EMA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11341,
"name": "naxitamab",
"type": "Antibody",
"abbreviation": "",
"inn": "naxitamab",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7246,
"name": "nebivolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nebivolol",
"approvalSource": "FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8090,
"name": "necitumumab",
"type": "Antibody",
"abbreviation": "",
"inn": "necitumumab",
"approvalSource": "FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7607,
"name": "nedocromil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nedocromil",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13615,
"name": "nedosiran",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "nedosiran",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7247,
"name": "nefazodone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nefazodone",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7090,
"name": "nelarabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nelarabine",
"approvalSource": "FDA (2005), EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11090,
"name": "nelfinavir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nelfinavir",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8720,
"name": "nemolizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "nemolizumab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10836,
"name": "nemonoxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nemonoxacin",
"approvalSource": "Taiwan (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 709,
"name": "neomycin",
"type": "Natural product",
"abbreviation": "",
"inn": "framycetin",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8993,
"name": "neostigmine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "neostigmine bromide",
"approvalSource": "FDA",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7564,
"name": "nepafenac",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nepafenac",
"approvalSource": "FDA (2005), EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7565
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12518,
"name": "nerandomilast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5686,
"name": "neratinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "neratinib",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9322,
"name": "netarsudil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "netarsudil",
"approvalSource": "FDA (2017), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12159,
"name": "netilmicin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "netilmicin",
"approvalSource": "FDA (1983), UK (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5742,
"name": "netupitant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "netupitant",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12676,
"name": "nevirapine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nevirapine",
"approvalSource": "FDA (1996), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5026,
"name": "NGF",
"type": "Peptide",
"abbreviation": "",
"inn": "cenegermin",
"approvalSource": "EMA (2017), FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 2559,
"name": "nicardipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nicardipine",
"approvalSource": "FDA (1988)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8494,
"name": "niclosamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2411,
"name": "nicorandil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nicorandil",
"approvalSource": "UK (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2585,
"name": "nicotine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2514,
"name": "nifedipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nifedipine",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2439,
"name": "niflumic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "niflumic acid",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12348,
"name": "nifuratel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nifuratel",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12358,
"name": "nifuroxazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nifuroxazide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12364,
"name": "nifurtimox",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nifurtimox",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12346,
"name": "nifurtoinol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nifurtoinol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5697,
"name": "nilotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nilotinib",
"approvalSource": "FDA & EMA (2007)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2864,
"name": "nilutamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nilutamide",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7401,
"name": "nimesulide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nimesulide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2523,
"name": "nimodipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nimodipine",
"approvalSource": "FDA (1988)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7988,
"name": "nimotuzumab",
"type": "Antibody",
"abbreviation": "",
"inn": "nimotuzumab",
"approvalSource": "China, India, others (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5936,
"name": "nintedanib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nintedanib",
"approvalSource": "FDA & EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13876,
"name": "nipocalimab",
"type": "Antibody",
"abbreviation": "",
"inn": "nipocalimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8275,
"name": "niraparib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "niraparib",
"approvalSource": "EMA & FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11503,
"name": "nirmatrelvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nirmatrelvir",
"approvalSource": "UK MHRA (2021), EMA (2022), FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7746,
"name": "nirogacestat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nirogacestat",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2524,
"name": "nisoldipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nisoldipine",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6834,
"name": "nitisinone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nitisinone",
"approvalSource": "FDA (2002), EMA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2334,
"name": "nitrendipine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nitrendipine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12366,
"name": "nitrofural",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nitrofural",
"approvalSource": "FDA (1945)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10917,
"name": "nitrofurantoin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nitrofurantoin",
"approvalSource": "FDA (1953), UK (2000)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7053,
"name": "nitroglycerin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (no history prior to 1981)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13964,
"name": "nitroxoline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nitroxoline",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7335,
"name": "nivolumab",
"type": "Antibody",
"abbreviation": "",
"inn": "nivolumab",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7248,
"name": "nizatidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nizatidine",
"approvalSource": "FDA (1988)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 316,
"name": "N-methyl scopolamine",
"type": "Synthetic organic",
"abbreviation": "NMS",
"inn": "",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2509,
"name": "NO",
"type": "Inorganic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1999), EMA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
9551
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11245,
"name": "nomegestrol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "UK (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4792,
"name": "nomifensine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nomifensine",
"approvalSource": "FDA (approval date not specified, withdrawn 1992)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 505,
"name": "(-)-noradrenaline",
"type": "Metabolite",
"abbreviation": "",
"inn": "norepinephrine",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7391
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4265,
"name": "nordihydroguiaretic acid",
"type": "Natural product",
"abbreviation": "NDGA",
"inn": "masoprocol",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2880,
"name": "norethisterone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "norethisterone",
"approvalSource": "FDA (1973)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12408,
"name": "norfloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "norfloxacin",
"approvalSource": "FDA (1986), EMA",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7091,
"name": "norgestimate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "norgestimate",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2404,
"name": "nortriptyline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "nortriptyline",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12021,
"name": "novobiocin",
"type": "Natural product",
"abbreviation": "",
"inn": "novobiocin",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13847,
"name": "NP10679",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9416,
"name": "nusinersen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "nusinersen",
"approvalSource": "FDA (2016), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3435,
"name": "obeticholic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "obeticholic acid",
"approvalSource": "EMA & FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13342,
"name": "obiltoxaximab",
"type": "Antibody",
"abbreviation": "",
"inn": "obiltoxaximab",
"approvalSource": "FDA (2016), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6941,
"name": "obinutuzumab",
"type": "Antibody",
"abbreviation": "",
"inn": "obinutuzumab",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7580,
"name": "ocrelizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "ocrelizumab",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7446,
"name": "ocriplasmin",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 2055,
"name": "octreotide",
"type": "Peptide",
"abbreviation": "",
"inn": "octreotide",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 11194,
"name": "odevixibat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "odevixibat",
"approvalSource": "EMA & FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12690,
"name": "odronextamab",
"type": "Antibody",
"abbreviation": "",
"inn": "odronextamab",
"approvalSource": "EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6778,
"name": "ofatumumab",
"type": "Antibody",
"abbreviation": "",
"inn": "ofatumumab",
"approvalSource": "FDA (2009), EMA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10918,
"name": "ofloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ofloxacin",
"approvalSource": "FDA (1990), UK (1992)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 47,
"name": "olanzapine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "olanzapine",
"approvalSource": "EMA & FDA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7519,
"name": "olaparib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "olaparib",
"approvalSource": "EMA & FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9172,
"name": "olaratumab",
"type": "Antibody",
"abbreviation": "",
"inn": "olaratumab",
"approvalSource": "EMA & FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13280,
"name": "oleandomycin",
"type": "Natural product",
"abbreviation": "",
"inn": "oleandomycin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13658,
"name": "olezarsen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "olezarsen",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7334,
"name": "oliceridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oliceridine",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 591,
"name": "olmesartan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "olmesartan medoxomil",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9196,
"name": "olmutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "olmutinib",
"approvalSource": "South Korea (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7543,
"name": "olodaterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "olodaterol",
"approvalSource": "FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7249,
"name": "olopatadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "olopatadine",
"approvalSource": "FDA (1996), EMA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11578,
"name": "olsalazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "olsalazine",
"approvalSource": "FDA (1997), UK (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2700
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10319,
"name": "olutasidenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "olutasidenib",
"approvalSource": "FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10630,
"name": "olverembatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "olverembatinib",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7454,
"name": "omacetaxine mepesuccinate",
"type": "Natural product",
"abbreviation": "",
"inn": "omacetaxine mepesuccinate",
"approvalSource": "FDA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10839,
"name": "omadacycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "omadacycline",
"approvalSource": "FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6890,
"name": "omalizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "omalizumab",
"approvalSource": "FDA (2003), EMA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7573,
"name": "omaveloxolone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "omaveloxolone",
"approvalSource": "FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11272,
"name": "ombitasvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ombitasvir",
"approvalSource": "FDA (2015), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4279,
"name": "omeprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "omeprazole",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10315,
"name": "omidenepag",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "omidenepag",
"approvalSource": "FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2290,
"name": "ondansetron",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ondansetron",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13787,
"name": "ongericimab",
"type": "Antibody",
"abbreviation": "",
"inn": "ongericimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8988,
"name": "opicapone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "opicapone",
"approvalSource": "EMA & UK (2016), FDA 2020",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11247,
"name": "opipramol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "opipramol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6971,
"name": "oprelvekin",
"type": "Peptide",
"abbreviation": "",
"inn": "oprelvekin",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7250,
"name": "orciprenaline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "orciprenaline",
"approvalSource": "FDA (1973)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10629,
"name": "orelabrutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "orelabrutinib",
"approvalSource": "China (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10877,
"name": "oritavancin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oritavancin",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5277,
"name": "orlistat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "orlistat",
"approvalSource": "FDA (1999), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7251,
"name": "orphenadrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "orphenadrine",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11427,
"name": "oseltamivir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oseltamivir",
"approvalSource": "FDA (1999), EMA (2002)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8310,
"name": "osilodrostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "osilodrostat",
"approvalSource": "EMA & FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7719,
"name": "osimertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "osimertinib",
"approvalSource": "FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7349,
"name": "ospemifene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ospemifene",
"approvalSource": "FDA (2013), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4826,
"name": "ouabain",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10943,
"name": "oxacillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxacillin",
"approvalSource": "FDA (1971)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7433,
"name": "oxaliplatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxaliplatin",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7092,
"name": "oxandrolone",
"type": "Metabolite",
"abbreviation": "",
"inn": "oxandrolone",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10840,
"name": "oxantel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxantel",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7252,
"name": "oxaprozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxaprozin",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7253,
"name": "oxazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxazepam",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7254,
"name": "oxcarbazepine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "imidazole salicylate",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6835,
"name": "oxiglutatione",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxiglutatione",
"approvalSource": "FDA (2008)-see Comment",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12999,
"name": "oxolinic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxolinic acid",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7255,
"name": "oxprenolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxprenolol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7123,
"name": "oxybuprocaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxybuprocaine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 359,
"name": "oxybutynin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxybutynin",
"approvalSource": "FDA (1975), EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7093,
"name": "oxycodone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxycodone",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 124,
"name": "oxymetazoline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxymetazoline",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7094,
"name": "oxymorphone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxymorphone",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7256,
"name": "oxyphencyclimine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxyphencyclimine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7257,
"name": "oxyphenonium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxyphenonium bromide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10919,
"name": "oxytetracycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "oxytetracycline",
"approvalSource": "FDA (1964), UK (2011)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2174,
"name": "oxytocin",
"type": "Peptide",
"abbreviation": "OT",
"inn": "oxytocin",
"approvalSource": "FDA (1980)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human, Mouse, Rat"
},
{
"ligandId": 9866,
"name": "ozagrel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ozagrel",
"approvalSource": "China and Japan only",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8709,
"name": "ozanimod",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ozanimod",
"approvalSource": "EMA & FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10841,
"name": "ozenoxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ozenoxacin",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11772,
"name": "pabinafusp alfa",
"type": "Antibody",
"abbreviation": "",
"inn": "pabinafusp alfa",
"approvalSource": "Japan (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2770,
"name": "paclitaxel",
"type": "Natural product",
"abbreviation": "",
"inn": "paclitaxel",
"approvalSource": "FDA (1992), EMA (2008)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7793,
"name": "pacritinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pacritinib",
"approvalSource": "FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7380,
"name": "palbociclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "palbociclib",
"approvalSource": "FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6954,
"name": "palifermin",
"type": "Peptide",
"abbreviation": "",
"inn": "palifermin",
"approvalSource": "FDA (2004), EMA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7258,
"name": "paliperidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "paliperidone",
"approvalSource": "FDA (2006), EMA (2007)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
96
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7486,
"name": "palonosetron",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "palonosetron",
"approvalSource": "FDA (2003), EMA (2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13484,
"name": "palopegteriparatide",
"type": "Peptide",
"abbreviation": "",
"inn": "palopegteriparatide",
"approvalSource": "EMA (2023), FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 8276,
"name": "palovarotene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "palovarotene",
"approvalSource": "Canada (2022), FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14237,
"name": "paltusotine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "paltusotine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7259,
"name": "pamidronic acid",
"type": "Synthetic organic",
"abbreviation": "disodium pamidronate",
"inn": "pamidronic acid",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12345,
"name": "pamiparib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pamiparib",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4001,
"name": "pancuronium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pancuronium bromide",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12184,
"name": "panipenem",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "panipenem",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6883,
"name": "panitumumab",
"type": "Antibody",
"abbreviation": "",
"inn": "panitumumab",
"approvalSource": "FDA (2006), EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7489,
"name": "panobinostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "panobinostat",
"approvalSource": "EMA & FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7260,
"name": "pantoprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pantoprazole",
"approvalSource": "FDA (2000), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13147,
"name": "papaverine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13652,
"name": "para-aminosalicylic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA, EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5239,
"name": "paracetamol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "paracetamol",
"approvalSource": "FDA (1968)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7261,
"name": "paramethadione",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "paramethadione",
"approvalSource": "FDA (1949)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2895,
"name": "parecoxib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "parecoxib",
"approvalSource": "UK (2002), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2894
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7262,
"name": "pargyline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pargyline",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2791,
"name": "paricalcitol",
"type": "Metabolite",
"abbreviation": "",
"inn": "paricalcitol",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11273,
"name": "paritaprevir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "paritaprevir",
"approvalSource": "FDA (2015), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12160,
"name": "paromomycin",
"type": "Natural product",
"abbreviation": "",
"inn": "paromomycin",
"approvalSource": "FDA (1969)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4790,
"name": "paroxetine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "paroxetine",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2018,
"name": "pasireotide",
"type": "Peptide",
"abbreviation": "",
"inn": "pasireotide",
"approvalSource": "FDA and EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 13611,
"name": "patisiran",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "patisiran",
"approvalSource": "EMA & EMA & FDA (2018), UK MHRA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5698,
"name": "pazopanib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pazopanib",
"approvalSource": "FDA (2009), EMA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12410,
"name": "pazufloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pazufloxacin",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5039,
"name": "PDGF BB",
"type": "Peptide",
"abbreviation": "",
"inn": "becaplermin",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
5043
],
"species": "Human"
},
{
"ligandId": 9782,
"name": "pecazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pecazine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8315,
"name": "peficitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "peficitinib",
"approvalSource": "Japan (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12411,
"name": "pefloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pefloxacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6836,
"name": "pegaptanib",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "pegaptanib",
"approvalSource": "FDA (2004), EMA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13826,
"name": "pegcetacoplan",
"type": "Peptide",
"abbreviation": "",
"inn": "pegcetacoplan",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6969,
"name": "pegfilgrastim",
"type": "Peptide",
"abbreviation": "",
"inn": "pegfilgrastim",
"approvalSource": "FDA and EMA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7447,
"name": "peginesatide",
"type": "Peptide",
"abbreviation": "",
"inn": "peginesatide",
"approvalSource": "FDA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7462,
"name": "peginterferon alfa-2b",
"type": "Peptide",
"abbreviation": "",
"inn": "peginterferon alfa-2b",
"approvalSource": "EMA (2000), FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7637,
"name": "peginterferon beta-1a",
"type": "Peptide",
"abbreviation": "",
"inn": "peginterferon beta-1a",
"approvalSource": "EMA and FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7463,
"name": "pegloticase",
"type": "Peptide",
"abbreviation": "",
"inn": "pegloticase",
"approvalSource": "FDA (2010), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7485,
"name": "pegvisomant",
"type": "Peptide",
"abbreviation": "",
"inn": "pegvisomant",
"approvalSource": "FDA (2003), EMA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7499,
"name": "pembrolizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "pembrolizumab",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6837,
"name": "pemetrexed",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pemetrexed",
"approvalSource": "FDA (2004), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9767,
"name": "pemigatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pemigatinib",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7329,
"name": "pemirolast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pemirolast",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12808,
"name": "penamecillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "penamecillin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
4796
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7263,
"name": "penbutolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "penbutolol",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7264,
"name": "penicillamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "penicillamine",
"approvalSource": "FDA (1970)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4796,
"name": "penicillin G",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "benethamine penicillin,benzathine benzylpenicillin,benzylpenicillin,clemizole penicillin,phenyracillin",
"approvalSource": "FDA (1947)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
12808
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12347,
"name": "penpulimab",
"type": "Antibody",
"abbreviation": "",
"inn": "penpulimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 870,
"name": "pentagastrin",
"type": "Peptide",
"abbreviation": "",
"inn": "pentagastrin",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 1606,
"name": "(-)-pentazocine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pentazocine",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5480,
"name": "pentobarbitone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pentobarbital",
"approvalSource": "FDA (1973, prior history not available)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4805,
"name": "pentostatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pentostatin",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7095,
"name": "pentoxifylline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pentoxifylline",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
9225
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7050,
"name": "perampanel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "perampanel",
"approvalSource": "FDA and EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 48,
"name": "pergolide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pergolide",
"approvalSource": "FDA (1988)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9216,
"name": "periciazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "periciazine",
"approvalSource": "UK (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6367,
"name": "perindopril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "perindopril",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6373
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6373,
"name": "perindoprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "perindoprilat",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6367
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7556,
"name": "perospirone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 209,
"name": "perphenazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "perphenazine",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5046,
"name": "pertuzumab",
"type": "Antibody",
"abbreviation": "",
"inn": "pertuzumab",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7221,
"name": "pethidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pethidine",
"approvalSource": "FDA (1942)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8710,
"name": "pexidartinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pexidartinib",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1882,
"name": "PGE1",
"type": "Metabolite",
"abbreviation": "",
"inn": "alprostadil",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1883,
"name": "PGE2",
"type": "Metabolite",
"abbreviation": "",
"inn": "dinoprostone",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1915,
"name": "PGI2",
"type": "Metabolite",
"abbreviation": "",
"inn": "epoprostenol",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7265,
"name": "phenacemide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenacemide",
"approvalSource": "FDA (1951)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7402,
"name": "phenacetin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenacetin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7616,
"name": "phenazopyridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenazopyridine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14332,
"name": "phendimetrazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7266,
"name": "phenelzine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenelzine",
"approvalSource": "FDA (1961)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12275,
"name": "pheneticillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pheneticillin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6838,
"name": "phenindione",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenindione",
"approvalSource": "FDA (approval date not available)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7267,
"name": "pheniramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pheniramine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2804,
"name": "phenobarbital",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenobarbital",
"approvalSource": "FDA (no date available)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7268,
"name": "phenoxybenzamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenoxybenzamine",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10920,
"name": "phenoxymethylpenicillin",
"type": "Natural product",
"abbreviation": "",
"inn": "phenoxymethylpenicillin",
"approvalSource": "FDA (1958), UK (1998)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6839,
"name": "phenprocoumon",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenprocoumon",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7269,
"name": "phentermine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phentermine",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 502,
"name": "phentolamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phentolamine",
"approvalSource": "FDA (1952)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7270,
"name": "phenylbutazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenylbutazone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8480,
"name": "phenylbutyrate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1996), EMA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 485,
"name": "phenylephrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenylephrine",
"approvalSource": "FDA (1952)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2624,
"name": "phenytoin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "phenytoin",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7190
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9086,
"name": "pholcodine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pholcodine",
"approvalSource": "UK (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6598,
"name": "physostigmine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11268,
"name": "pibrentasvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pibrentasvir",
"approvalSource": "EMA & FDA (2017)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14398,
"name": "picankibart",
"type": "Antibody",
"abbreviation": "",
"inn": "picankibart",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 305,
"name": "pilocarpine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8423,
"name": "pimavanserin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pimavanserin",
"approvalSource": "FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6783,
"name": "pimecrolimus",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pimecrolimus",
"approvalSource": "FDA (2001), EMA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12873,
"name": "pimicotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 90,
"name": "pimozide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pimozide",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2412,
"name": "pinacidil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pinacidil",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 91,
"name": "pindolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pindolol",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2694,
"name": "pioglitazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pioglitazone",
"approvalSource": "FDA (1999), EMA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12774,
"name": "pipemidic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pipemidic acid",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10921,
"name": "piperacillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "piperacillin",
"approvalSource": "FDA (1981), UK (2011)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10025,
"name": "piperaquine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "piperaquine",
"approvalSource": "EMA (2011) in combination with artenimol",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7271,
"name": "pipobroman",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pipobroman",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7557,
"name": "pipotiazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pipotiazine",
"approvalSource": "UK (1980)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4288,
"name": "piracetam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "piracetam",
"approvalSource": "UK (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7272,
"name": "pirbuterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pirbuterol",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 328,
"name": "pirenzepine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pirenzepine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7532,
"name": "pirfenidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pirfenidone",
"approvalSource": "EMA (2011), FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6638,
"name": "pirlindole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pirlindole",
"approvalSource": "Russia only",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12475,
"name": "piromidic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "piromidic acid",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7273,
"name": "piroxicam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "piroxicam",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11628,
"name": "pirtobrutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pirtobrutinib",
"approvalSource": "FDA & EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3035,
"name": "pitavastatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pitavastatin",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8924,
"name": "pitolisant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pitolisant",
"approvalSource": "EMA (2016), FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10922,
"name": "pivmecillinam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pivmecillinam",
"approvalSource": "UK (1977), FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
12813
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7544,
"name": "pixantrone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pixantrone",
"approvalSource": "EMA and UK (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 93,
"name": "pizotifen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pizotifen",
"approvalSource": "UK (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10847,
"name": "plazomicin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "plazomicin",
"approvalSource": "FDA (2018)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9069,
"name": "plecanatide",
"type": "Peptide",
"abbreviation": "",
"inn": "plecanatide",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 844,
"name": "plerixafor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "plerixafor",
"approvalSource": "FDA (2008), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11396,
"name": "plitidepsin",
"type": "Natural product",
"abbreviation": "",
"inn": "plitidepsin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13642,
"name": "plozasiran",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "plozasiran",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13598,
"name": "podofilox",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (pre-1990)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8404,
"name": "polatuzumab vedotin",
"type": "Antibody",
"abbreviation": "",
"inn": "polatuzumab vedotin",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8316,
"name": "polmacoxib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "polmacoxib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10338,
"name": "polymyxin B",
"type": "Peptide",
"abbreviation": "",
"inn": "polymyxin B",
"approvalSource": "FDA (1964, no prior history available)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7274,
"name": "polythiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "polythiazide",
"approvalSource": "FDA (1961)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7348,
"name": "pomalidomide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pomalidomide",
"approvalSource": "FDA and EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5890,
"name": "ponatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ponatinib",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9320,
"name": "ponesimod",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ponesimod",
"approvalSource": "EMA & FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11428,
"name": "posaconazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "posaconazole",
"approvalSource": "EMA (2005), FDA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12900,
"name": "pozelimab",
"type": "Antibody",
"abbreviation": "",
"inn": "pozelimab",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 555,
"name": "practolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "practolol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6840,
"name": "pralatrexate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pralatrexate",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7597,
"name": "pralidoxime",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pralidoxime iodide",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1092,
"name": "pralmorelin",
"type": "Peptide",
"abbreviation": "",
"inn": "pralmorelin",
"approvalSource": "Japan only",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10033,
"name": "pralsetinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pralsetinib",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 953,
"name": "pramipexole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pramipexole",
"approvalSource": "FDA and EMA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7482,
"name": "pramlintide",
"type": "Peptide",
"abbreviation": "",
"inn": "pramlintide",
"approvalSource": "FDA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 3634,
"name": "pranlukast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pranlukast",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7562,
"name": "prasugrel",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prasugrel",
"approvalSource": "FDA and EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
1771
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2953,
"name": "pravastatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pravastatin",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7275,
"name": "prazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prazepam",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 503,
"name": "prazosin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prazosin",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7605,
"name": "prednicarbate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prednicarbate",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2866,
"name": "prednisolone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prednisolone",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7096,
"name": "prednisone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prednisone",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5484,
"name": "pregabalin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pregabalin",
"approvalSource": "FDA and EMA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2376,
"name": "pregnenolone",
"type": "Metabolite",
"abbreviation": "",
"inn": "pregnenolone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11172,
"name": "pretomanid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pretomanid",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7276,
"name": "prilocaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prilocaine",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9952,
"name": "primaquine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "primaquine",
"approvalSource": "FDA (1952)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5338,
"name": "primidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "primidone",
"approvalSource": "FDA (1954)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12934,
"name": "pristinamycin IA",
"type": "Natural product",
"abbreviation": "",
"inn": "pristinamycin",
"approvalSource": "France, 1995",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12933,
"name": "pristinamycin IIA",
"type": "Natural product",
"abbreviation": "",
"inn": "pristinamycin",
"approvalSource": "France, 1995",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4357,
"name": "probenecid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "probenecid",
"approvalSource": "FDA (1951)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7277,
"name": "probucol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "probucol",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4811,
"name": "procainamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "procainamide",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4291,
"name": "procaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "procaine",
"approvalSource": "FDA (1972)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7278,
"name": "procarbazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "procarbazine",
"approvalSource": "FDA (1969)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3464,
"name": "procaterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "procaterol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7279,
"name": "prochlorperazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prochlorperazine",
"approvalSource": "FDA (1956)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7280,
"name": "procyclidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "procyclidine",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2377,
"name": "progesterone",
"type": "Metabolite",
"abbreviation": "",
"inn": "progesterone",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9676,
"name": "proguanil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "proguanil",
"approvalSource": "FDA (2000) in combination with atovaquone",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7281,
"name": "promazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "promazine",
"approvalSource": "FDA (1956)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7282,
"name": "promethazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "promethazine",
"approvalSource": "FDA (1951)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2561,
"name": "propafenone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "propafenone",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 329,
"name": "propantheline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "propantheline bromide",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7283,
"name": "proparacaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "proxymetacaine",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7284,
"name": "propiomazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "propiomazine",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5464,
"name": "propofol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "propofol",
"approvalSource": "FDA (1989)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7475
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 564,
"name": "propranolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "propranolol",
"approvalSource": "FDA (1967), EMA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6650,
"name": "propylthiouracil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "propylthiouracil",
"approvalSource": "FDA (1947)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14280,
"name": "protionamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "protionamide",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7285,
"name": "protriptyline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "protriptyline",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 243,
"name": "prucalopride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prucalopride",
"approvalSource": "EMA (2009), FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12860,
"name": "prulifloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prulifloxacin",
"approvalSource": "EMA, Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14396,
"name": "prusogliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "prusogliptin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7286,
"name": "pseudoephedrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pseudoephedrine",
"approvalSource": "FDA (1975)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1785,
"name": "PTH",
"type": "Peptide",
"abbreviation": "",
"inn": "parathyroid hormone",
"approvalSource": "FDA (2015), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 13886,
"name": "pucolentimab",
"type": "Antibody",
"abbreviation": "",
"inn": "pucotenlimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7287,
"name": "pyrazinamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pyrazinamide",
"approvalSource": "FDA (no history prior to 1971)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8994,
"name": "pyridostigmine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pyridostigmine bromide",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4800,
"name": "pyrimethamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "pyrimethamine",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9662,
"name": "pyrotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "China (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7288,
"name": "quazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "quazepam",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 50,
"name": "quetiapine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "quetiapine",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6350,
"name": "quinapril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "quinapril",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6352
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6352,
"name": "quinaprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "quinaprilat",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6350
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7097,
"name": "quinestrol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "quinestrol",
"approvalSource": "FDA (date unknown)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7289,
"name": "quinethazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "quinethazone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2342,
"name": "quinidine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2510,
"name": "quinine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2005, as quinine sulfate, previous history unspecified)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10798,
"name": "quinupristin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "quinupristin",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5658,
"name": "quizartinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "quizartinib",
"approvalSource": "Japan (2019), EMA & FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7290,
"name": "rabeprazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rabeprazole",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11654,
"name": "racecadotril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "racecadotril",
"approvalSource": "UK (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
5278
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7995,
"name": "racotumomab",
"type": "Antibody",
"abbreviation": "",
"inn": "racotumomab",
"approvalSource": "Cuba and Argentina (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7814,
"name": "radotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "radotinib",
"approvalSource": "South Korea (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2820,
"name": "raloxifene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "raloxifene",
"approvalSource": "FDA (1997), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11571,
"name": "raltegravir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "raltegravir",
"approvalSource": "EMA & FDA (2007)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7403,
"name": "raltitrexed",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "raltitrexed",
"approvalSource": "EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1356,
"name": "ramelteon",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ramelteon",
"approvalSource": "FDA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6339,
"name": "ramipril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ramipril",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6344
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6344,
"name": "ramiprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ramiprilat",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6339
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7390,
"name": "ramucirumab",
"type": "Antibody",
"abbreviation": "",
"inn": "ramucirumab",
"approvalSource": "FDA & EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6779,
"name": "ranibizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "ranibizumab",
"approvalSource": "FDA (2006), EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1234,
"name": "ranitidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ranitidine",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": true,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7291,
"name": "ranolazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ranolazine",
"approvalSource": "FDA (2006), EMA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6641,
"name": "rasagiline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rasagiline",
"approvalSource": "EMA (2005), FDA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7467,
"name": "rasburicase",
"type": "Peptide",
"abbreviation": "",
"inn": "rasburicase",
"approvalSource": "FDA and EMA (2009)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10168,
"name": "ravulizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "ravulizumab",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13344,
"name": "raxibacumab",
"type": "Antibody",
"abbreviation": "",
"inn": "raxibacumab",
"approvalSource": "FDA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 871,
"name": "rebamipide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rebamipide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4808,
"name": "reboxetine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "reboxetine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14196,
"name": "recaticimab",
"type": "Antibody",
"abbreviation": "",
"inn": "recaticimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5596,
"name": "regadenoson",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "regadenoson",
"approvalSource": "FDA (2008), EMA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11332,
"name": "regdanvimab",
"type": "Antibody",
"abbreviation": "",
"inn": "regdanvimab",
"approvalSource": "South Korea & EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5891,
"name": "regorafenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "regorafenib",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9536,
"name": "relatlimab",
"type": "Antibody",
"abbreviation": "",
"inn": "relatlimab",
"approvalSource": "EMA & FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10852,
"name": "relebactam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "relebactam",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5586,
"name": "relugolix",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "relugolix",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10715,
"name": "remdesivir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "remdesivir",
"approvalSource": "FDA & EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
11445
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10457,
"name": "remibrutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "remibrutinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7292,
"name": "remifentanil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "remifentanil",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8442,
"name": "remimazolam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "remimazolam",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6841,
"name": "repaglinide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "repaglinide",
"approvalSource": "FDA (1997), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10316,
"name": "repotrectinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "repotrectinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7098,
"name": "rescinnamine",
"type": "Natural product",
"abbreviation": "",
"inn": "rescinnamine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4823,
"name": "reserpine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "reserpine",
"approvalSource": "FDA (1955)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8091,
"name": "reslizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "reslizumab",
"approvalSource": "EMA & FDA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12026,
"name": "resmetirom",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "resmetirom",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11035,
"name": "retapamulin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "retapamulin",
"approvalSource": "FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11583,
"name": "retifanlimab",
"type": "Antibody",
"abbreviation": "",
"inn": "retifanlimab",
"approvalSource": "FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2601,
"name": "retigabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "retigabine",
"approvalSource": "FDA and EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12007,
"name": "revaprazan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "revaprazan",
"approvalSource": "S Korea (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10129,
"name": "revefenacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "revefenacin",
"approvalSource": "FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11882,
"name": "revumenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "revumenib",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10628,
"name": "rezivertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rezivertinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12798,
"name": "rezvilutamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rezvilutamide",
"approvalSource": "China NMPA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6842,
"name": "ribavirin",
"type": "Synthetic organic",
"abbreviation": "RBV",
"inn": "ribavirin",
"approvalSource": "FDA (1985), EMA (1999)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7383,
"name": "ribociclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ribociclib",
"approvalSource": "FDA & EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12015,
"name": "rifabutin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rifabutin",
"approvalSource": "FDA (1992), UK (2003)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2765,
"name": "rifampicin",
"type": "Natural product",
"abbreviation": "",
"inn": "rifampicin",
"approvalSource": "FDA (1971)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4570,
"name": "rifamycin",
"type": "Natural product",
"abbreviation": "",
"inn": "rifamycin",
"approvalSource": "FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12014,
"name": "rifapentine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rifapentine",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12012,
"name": "rifaximin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rifaximin",
"approvalSource": "FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13356,
"name": "rilmenidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rilmenidine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6790,
"name": "rilonacept",
"type": "Peptide",
"abbreviation": "",
"inn": "rilonacept",
"approvalSource": "FDA (2008), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 11387,
"name": "rilpivirine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rilpivirine",
"approvalSource": "EMA & FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2326,
"name": "riluzole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "riluzole",
"approvalSource": "FDA (1995), EMA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
11375
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9993,
"name": "rilzabrutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rilzabrutinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10704,
"name": "rimegepant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rimegepant",
"approvalSource": "FDA (2020), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7099,
"name": "rimexolone",
"type": "Metabolite",
"abbreviation": "",
"inn": "rimexolone",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 743,
"name": "rimonabant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rimonabant",
"approvalSource": "EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5257,
"name": "riociguat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "riociguat",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10423,
"name": "ripasudil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ripasudil",
"approvalSource": "Japan (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9175,
"name": "ripretinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ripretinib",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8922,
"name": "risankizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "risankizumab",
"approvalSource": "Japan, FDA & EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11170,
"name": "risdiplam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "risdiplam",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3176,
"name": "risedronate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "risedronic acid",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 96,
"name": "risperidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "risperidone",
"approvalSource": "FDA (1993), EMA (2022)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7258
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9559,
"name": "ritlecitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ritlecitinib",
"approvalSource": "FDA, UK & EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7294,
"name": "ritodrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ritodrine",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8804,
"name": "ritonavir",
"type": "Synthetic organic",
"abbreviation": "RTV",
"inn": "ritonavir",
"approvalSource": "EMA & FDA (1996)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6780,
"name": "rituximab",
"type": "Antibody",
"abbreviation": "",
"inn": "rituximab",
"approvalSource": "FDA (1997), EMA (1998)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6388,
"name": "rivaroxaban",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rivaroxaban",
"approvalSource": "EMA (2008), FDA (2011)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6602,
"name": "rivastigmine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rivastigmine",
"approvalSource": "FDA (2000), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7648,
"name": "rivoceranib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rivoceranib",
"approvalSource": "2014 (Chinese NMPA)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 51,
"name": "rizatriptan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rizatriptan",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4003,
"name": "rocuronium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rocuronium bromide",
"approvalSource": "FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2893,
"name": "rofecoxib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rofecoxib",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6962,
"name": "roflumilast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "roflumilast",
"approvalSource": "EMA (2010), FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12879,
"name": "rokitamycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rokitamycin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5749,
"name": "rolapitant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rolapitant",
"approvalSource": "FDA (2015), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
14241
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12760,
"name": "rolitetracycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rolitetracycline",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10927
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7006,
"name": "romidepsin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "romidepsin",
"approvalSource": "FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6974,
"name": "romiplostim",
"type": "Peptide",
"abbreviation": "",
"inn": "romiplostim",
"approvalSource": "FDA (2008), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 8092,
"name": "romosozumab",
"type": "Antibody",
"abbreviation": "",
"inn": "romosozumab",
"approvalSource": "Japan, FDA and EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7295,
"name": "ropinirole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ropinirole",
"approvalSource": "FDA (1997), EMA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7602,
"name": "ropivacaine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ropivacaine",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1056,
"name": "rosiglitazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rosiglitazone",
"approvalSource": "FDA (1999), EMA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12474,
"name": "rosoxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rosoxacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2954,
"name": "rosuvastatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rosuvastatin",
"approvalSource": "FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 941,
"name": "rotigotine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rotigotine",
"approvalSource": "EMA (2006), FDA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8454,
"name": "roxadustat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "roxadustat",
"approvalSource": "EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1465,
"name": "roxithromycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "roxithromycin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9801,
"name": "rozanolixizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "rozanolixizumab",
"approvalSource": "FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7736,
"name": "rucaparib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rucaparib",
"approvalSource": "FDA (2016), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7470,
"name": "rufinamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rufinamide",
"approvalSource": "EMA (2007), FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12473,
"name": "rufloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rufloxacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10103,
"name": "rupatadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "rupatadine",
"approvalSource": "UK (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5688,
"name": "ruxolitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ruxolitinib",
"approvalSource": "FDA (2011), EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8253,
"name": "sacituzumab govitecan",
"type": "Antibody",
"abbreviation": "",
"inn": "sacituzumab govitecan",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13791,
"name": "sacituzumab tirumotecan",
"type": "Antibody",
"abbreviation": "",
"inn": "sacituzumab tirumotecan",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7857,
"name": "sacubitril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sacubitril",
"approvalSource": "EMA & FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7858
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8291,
"name": "safinamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "safinamide",
"approvalSource": "EMA (2015), FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 558,
"name": "salbutamol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "salbutamol",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4306,
"name": "salicylic acid",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 559,
"name": "salmeterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "salmeterol",
"approvalSource": "FDA (1994), EMA (2016)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10651,
"name": "samidorphan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "samidorphan",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5276,
"name": "sapropterin",
"type": "Metabolite",
"abbreviation": "",
"inn": "sapropterin",
"approvalSource": "FDA (2007), EMA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
14278
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4813,
"name": "saquinavir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "saquinavir",
"approvalSource": "FDA (1995), EMA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10857,
"name": "sarafloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sarafloxacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12921,
"name": "sarecycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sarecycline",
"approvalSource": "FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7905,
"name": "sargramostim",
"type": "Peptide",
"abbreviation": "",
"inn": "sargramostim",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7999,
"name": "sarilumab",
"type": "Antibody",
"abbreviation": "",
"inn": "sarilumab",
"approvalSource": "EMA & FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14341,
"name": "saroglitazar",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "saroglitazar",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 210,
"name": "sarpogrelate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sarpogrelate",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9093,
"name": "satralizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "satralizumab",
"approvalSource": "Canada, Japan and FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9918,
"name": "savolitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "savolitinib",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6316,
"name": "saxagliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "saxagliptin",
"approvalSource": "EMA & FDA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 330,
"name": "scopolamine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11947,
"name": "sebetralstat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sebetralstat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12925,
"name": "secnidazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "secnidazole",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7615,
"name": "secobarbital",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "secobarbital",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3643,
"name": "secretin",
"type": "Peptide",
"abbreviation": "",
"inn": "secretin human",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 8078,
"name": "secukinumab",
"type": "Antibody",
"abbreviation": "",
"inn": "secukinumab",
"approvalSource": "Japan (2014), FDA and EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11137,
"name": "seladelpar",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "seladelpar",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6639,
"name": "selegiline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "selegiline",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7552,
"name": "selexipag",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "selexipag",
"approvalSource": "FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
5852
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10036,
"name": "selinexor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "selinexor",
"approvalSource": "FDA (2019), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10318,
"name": "selpercatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "selpercatinib",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5665,
"name": "selumetinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "selumetinib",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9724,
"name": "semaglutide",
"type": "Peptide",
"abbreviation": "",
"inn": "semaglutide",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 11199,
"name": "senaparib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "senaparib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13939,
"name": "seniprutug",
"type": "Antibody",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14278,
"name": "sepiapterin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sepiapterin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
5276
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6966,
"name": "seractide acetate",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 11450,
"name": "serdexmethylphenidate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "serdexmethylphenidate",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7554
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6998,
"name": "sermorelin",
"type": "Peptide",
"abbreviation": "",
"inn": "sermorelin",
"approvalSource": "FDA (1990)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 13796,
"name": "serplulimab",
"type": "Antibody",
"abbreviation": "",
"inn": "serplulimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 98,
"name": "sertindole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sertindole",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4798,
"name": "sertraline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sertraline",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9272,
"name": "setmelanotide",
"type": "Peptide",
"abbreviation": "",
"inn": "setmelanotide ",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 13491,
"name": "sevabertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sevabertinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7296,
"name": "sevoflurane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sevoflurane",
"approvalSource": "FDA (1995), EMA (2002)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13760,
"name": "SH-1028",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12102,
"name": "sibeprenlimab",
"type": "Antibody",
"abbreviation": "",
"inn": "sibeprenlimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2586,
"name": "sibutramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sibutramine",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4743,
"name": "sildenafil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sildenafil",
"approvalSource": "EMA & FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 493,
"name": "silodosin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "silodosin",
"approvalSource": "FDA (2008), EMA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7396,
"name": "siltuximab",
"type": "Antibody",
"abbreviation": "",
"inn": "siltuximab",
"approvalSource": "EMA & FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12781,
"name": "simenafil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7367,
"name": "simeprevir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "simeprevir",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12960,
"name": "simnotrelvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "China NMPA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7640,
"name": "simotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "China only",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2955,
"name": "simvastatin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "simvastatin",
"approvalSource": "FDA (1991), EMA (2013)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12990,
"name": "sintilimab",
"type": "Antibody",
"abbreviation": "",
"inn": "sintilimab",
"approvalSource": "China (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13905,
"name": "sipavibart",
"type": "Antibody",
"abbreviation": "",
"inn": "sipavibart",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9289,
"name": "siponimod",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "siponimod",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6031,
"name": "sirolimus",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sirolimus",
"approvalSource": "FDA (1999), EMA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10858,
"name": "sisomicin",
"type": "Natural product",
"abbreviation": "",
"inn": "sisomicin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11040,
"name": "sitafloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sitafloxacin",
"approvalSource": "Japan (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6286,
"name": "sitagliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sitagliptin",
"approvalSource": "FDA (2006), EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3950,
"name": "sitaxsentan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sitaxentan",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12196,
"name": "sitokiren",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sitokiren",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6441,
"name": "sivelestat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sivelestat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9533,
"name": "SNP",
"type": "Inorganic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA 1988",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7368,
"name": "sofosbuvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sofosbuvir",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13426,
"name": "sofpironium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sofpironium bromide",
"approvalSource": "Japan (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7483,
"name": "solifenacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "solifenacin",
"approvalSource": "FDA (2004), UK (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10342,
"name": "solriamfetol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "solriamfetol",
"approvalSource": "FDA (2019), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12013,
"name": "somatrogon",
"type": "Peptide",
"abbreviation": "",
"inn": "somatrogon",
"approvalSource": "EMA (2022), FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 8199,
"name": "sonidegib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sonidegib",
"approvalSource": "EMA & FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13354,
"name": "sonrotoclax",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sonrotoclax",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5711,
"name": "sorafenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sorafenib",
"approvalSource": "FDA (2005), EMA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8312,
"name": "sotagliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sotagliflozin",
"approvalSource": "EMA (2019), FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7297,
"name": "sotalol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sotalol",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12962,
"name": "sotatercept",
"type": "Antibody",
"abbreviation": "",
"inn": "sotatercept",
"approvalSource": "EMA & FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10678,
"name": "sotorasib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sotorasib",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11333,
"name": "sotrovimab",
"type": "Antibody",
"abbreviation": "",
"inn": "sotrovimab",
"approvalSource": "UK & EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3886,
"name": "sovateltide",
"type": "Peptide",
"abbreviation": "",
"inn": "sovateltide",
"approvalSource": "India CDSCO (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10860,
"name": "sparfloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sparfloxacin",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8448,
"name": "sparsentan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sparsentan",
"approvalSource": "FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11127,
"name": "spectinomycin",
"type": "Natural product",
"abbreviation": "",
"inn": "spectinomycin",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12169,
"name": "spesolimab",
"type": "Antibody",
"abbreviation": "",
"inn": "spesolimab",
"approvalSource": "FDA and EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13312,
"name": "spiramycin",
"type": "Natural product",
"abbreviation": "",
"inn": "spiramycin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6575,
"name": "spirapril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "spirapril",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6576
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6576,
"name": "spiraprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "spiraprilat",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6575
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2875,
"name": "spironolactone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "spironolactone",
"approvalSource": "FDA (1960), EMA (2023)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10369,
"name": "stanozolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "stanozolol",
"approvalSource": "FDA (1962)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13785,
"name": "stapokibart",
"type": "Antibody",
"abbreviation": "",
"inn": "stapokibart",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12678,
"name": "stavudine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "stavudine",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5469,
"name": "stiripentol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "stiripentol",
"approvalSource": "EMA (2007), FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10923,
"name": "streptomycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "streptomycin",
"approvalSource": "FDA (1946)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4004,
"name": "succinylcholine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "suxamethonium chloride",
"approvalSource": "FDA (1952)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7055,
"name": "sucralfate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sucralfate",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3534,
"name": "sufentanil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sufentanil",
"approvalSource": "FDA (1984), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5826,
"name": "sufinpyrazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfinpyrazone",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12342,
"name": "sugemalimab",
"type": "Antibody",
"abbreviation": "",
"inn": "sugemalimab",
"approvalSource": "China (2021), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10769,
"name": "sulbactam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulbactam",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
12290
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12632,
"name": "sulfabenzamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfabenzamide",
"approvalSource": "FDA (1945)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12633,
"name": "sulfacetamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfacetamide",
"approvalSource": "FDA (1945)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12634,
"name": "sulfachlorpyridazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfachlorpyridazine",
"approvalSource": "FDA",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12635,
"name": "sulfadiazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfadiazine",
"approvalSource": "FDA (1941), UK (2008)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12638,
"name": "sulfadimethoxine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfadimethoxine",
"approvalSource": "FDA (1958)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12642,
"name": "sulfadimidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfadimidine",
"approvalSource": "FDA (1949)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10173,
"name": "sulfadoxine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfadoxine",
"approvalSource": "FDA (1981) in combination with pyrimethamine",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12639,
"name": "sulfaguanidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfaguanidine",
"approvalSource": "FDA (1941)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13711,
"name": "sulfamazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfamazone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12640,
"name": "sulfamerazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfamerazine",
"approvalSource": "FDA (1949)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12683,
"name": "sulfamethizole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfamethizole",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10933,
"name": "sulfamethoxazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfamethoxazole",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12686,
"name": "sulfamethoxypyridazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfamethoxypyridazine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12641,
"name": "sulfametoxydiazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfametoxydiazine",
"approvalSource": "FDA (1966)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12702,
"name": "sulfametrole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfametrole",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12688,
"name": "sulfamonomethoxine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfamonomethoxine",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12744,
"name": "sulfamoxole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfamoxole",
"approvalSource": "1960",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12631,
"name": "sulfanilamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfanilamide",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
12743
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12698,
"name": "sulfapyridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfapyridine",
"approvalSource": "FDA (1939)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4840,
"name": "sulfasalazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfasalazine",
"approvalSource": "FDA (1950)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12699,
"name": "sulfathiazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfathiazole",
"approvalSource": "FDA (1945)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12700,
"name": "sulfisoxazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulfafurazole",
"approvalSource": "FDA (1948)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5425,
"name": "sulindac",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulindac",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10862,
"name": "sulopenem",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulopenem",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 958,
"name": "(-)-sulpiride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "levosulpiride,sulpiride",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5501,
"name": "sulpiride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sulpiride",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12290,
"name": "sultamicillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sultamicillin",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10896,
10769
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 54,
"name": "sumatriptan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sumatriptan",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5713,
"name": "sunitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sunitinib",
"approvalSource": "FDA and EMA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11672,
"name": "sunvozertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "sunvozertinib",
"approvalSource": "China (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7298,
"name": "suprofen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "suprofen",
"approvalSource": "FDA (no history prior to 1988)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1728,
"name": "suramin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "suramin sodium",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9769,
"name": "surufatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "surufatinib",
"approvalSource": "China (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9807,
"name": "sutimlimab",
"type": "Antibody",
"abbreviation": "",
"inn": "sutimlimab",
"approvalSource": "EMA & FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2890,
"name": "suvorexant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "suvorexant",
"approvalSource": "FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12630,
"name": "suzetrigine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "suzetrigine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6687,
"name": "tacrine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tacrine",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6784,
"name": "tacrolimus",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tacrolimus",
"approvalSource": "FDA (1994), EMA (2002)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7299,
"name": "tadalafil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tadalafil",
"approvalSource": "EMA (2002), FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8378,
"name": "tafamidis",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tafamidis",
"approvalSource": "EMA and UK (2011), FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11131,
"name": "tafasitamab",
"type": "Antibody",
"abbreviation": "",
"inn": "tafasitamab",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9722,
"name": "tafenoquine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tafenoquine",
"approvalSource": "FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": true,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7451,
"name": "tafluprost",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tafluprost",
"approvalSource": "FDA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
7452
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12517,
"name": "tafolecimab",
"type": "Antibody",
"abbreviation": "",
"inn": "tafolecimab",
"approvalSource": "China (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13795,
"name": "tagitanlimab",
"type": "Antibody",
"abbreviation": "",
"inn": "tagitanlimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12289,
"name": "talampicillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "talampicillin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
10896
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8313,
"name": "talazoparib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "talazoparib",
"approvalSource": "FDA (2018), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11198,
"name": "taletrectinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "taletrectinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7444,
"name": "taliglucerase alfa",
"type": "Peptide",
"abbreviation": "",
"inn": "taliglucerase alfa",
"approvalSource": "FDA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 12240,
"name": "talquetamab",
"type": "Antibody",
"abbreviation": "",
"inn": "talquetamab",
"approvalSource": "FDA & EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2648,
"name": "tamibarotene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tamibarotene",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1016,
"name": "tamoxifen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tamoxifen",
"approvalSource": "FDA (1977)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2817,
10204,
10203
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 488,
"name": "tamsulosin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tamsulosin",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7477,
"name": "tapentadol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tapentadol",
"approvalSource": "FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9686,
"name": "tapinarof",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tapinarof",
"approvalSource": "FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12969,
"name": "tarlatamab",
"type": "Antibody",
"abbreviation": "",
"inn": "tarlatamab",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7393,
"name": "tasimelteon",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tasimelteon",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11414,
"name": "tasurgratinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tasurgratinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13030,
"name": "taurolidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "taurolidine",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4746,
"name": "tauroursodeoxycholic acid",
"type": "Metabolite",
"abbreviation": "TUDA",
"inn": "ursodoxicoltaurine",
"approvalSource": "FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6952,
"name": "tazarotene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tazarotene",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7011,
"name": "tazemetostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tazemetostat",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7378,
"name": "tebentafusp",
"type": "Antibody",
"abbreviation": "",
"inn": "tebentafusp",
"approvalSource": "FDA & EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10864,
"name": "tebipenem pivoxil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tebipenem pivoxil",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12233,
"name": "teclistamab",
"type": "Antibody",
"abbreviation": "",
"inn": "teclistamab",
"approvalSource": "EMA & FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10865,
"name": "tedizolid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tedizolid",
"approvalSource": "FDA (2014), EMA (2015)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7049,
"name": "teduglutide",
"type": "Peptide",
"abbreviation": "",
"inn": "teduglutide",
"approvalSource": "FDA and EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10513,
"name": "tegafur",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tegafur",
"approvalSource": "EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 226,
"name": "tegaserod",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tegaserod",
"approvalSource": "FDA (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13434,
"name": "tegileridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tegileridine",
"approvalSource": "China (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12008,
"name": "tegoprazan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tegoprazan",
"approvalSource": "S Korea (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10924,
"name": "teicoplanin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "teicoplanin",
"approvalSource": "UK (1989)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10925,
"name": "telavancin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "telavancin",
"approvalSource": "FDA (2009), EMA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13908,
"name": "telisotuzumab vedotin",
"type": "Antibody",
"abbreviation": "",
"inn": "telisotuzumab vedotin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11827,
"name": "telitacicept",
"type": "Peptide",
"abbreviation": "",
"inn": "telitacicept",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10878,
"name": "telithromycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "telithromycin",
"approvalSource": "EMA (2001), FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 592,
"name": "telmisartan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "telmisartan",
"approvalSource": "EMA & FDA (1998)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9490,
"name": "telotristat ethyl",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "telotristat",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10866,
"name": "temafloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "temafloxacin",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7300,
"name": "temazepam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "temazepam",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11736,
"name": "temocapril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "temocapril",
"approvalSource": "Japan & Korea",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
11737
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10926,
"name": "temocillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "temocillin",
"approvalSource": "UK (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7301,
"name": "temozolomide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "temozolomide",
"approvalSource": "EMA and FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5892,
"name": "temsirolimus",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "temsirolimus",
"approvalSource": "FDA & EMA (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8449,
"name": "tenapanor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tenapanor",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9906,
"name": "teneligliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "teneligliptin",
"approvalSource": "Japan (2012), S Korea (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6843,
"name": "teniposide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "teniposide",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10948,
"name": "tenofovir",
"type": "Synthetic organic",
"abbreviation": "TDF",
"inn": "tenofovir",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14054,
"name": "tenofovir alafenamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tenofovir alafenamide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12252,
"name": "teplizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "teplizumab",
"approvalSource": "FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8293,
"name": "tepotinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tepotinib",
"approvalSource": "FDA, EMA & UK MHRA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10612,
"name": "teprotumumab",
"type": "Antibody",
"abbreviation": "",
"inn": "teprotumumab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7302,
"name": "terazosin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "terazosin",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 560,
"name": "terbutaline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "terbutaline",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6601
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2608,
"name": "terfenadine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "terfenadine",
"approvalSource": "FDA",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 56,
"name": "terguride",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "terguride",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6844,
"name": "teriflunomide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "teriflunomide",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6825
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4448,
"name": "teriparatide",
"type": "Peptide",
"abbreviation": "",
"inn": "teriparatide",
"approvalSource": "FDA (1987), EMA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 14307,
"name": "terizidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "terizidone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11241,
"name": "terlipressin",
"type": "Peptide",
"abbreviation": "",
"inn": "terlipressin",
"approvalSource": "UK (2001), FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 6959,
"name": "tesamorelin",
"type": "Peptide",
"abbreviation": "",
"inn": "tesamorelin",
"approvalSource": "FDA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7303,
"name": "testolactone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "testolactone",
"approvalSource": "FDA (1969)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2858,
"name": "testosterone",
"type": "Metabolite",
"abbreviation": "",
"inn": "testosterone",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
7100,
7628,
7629,
7630
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7630,
"name": "testosterone decanoate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2858
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7629,
"name": "testosterone isocaproate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2858
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7628,
"name": "testosterone phenylpropionate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2858
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7100,
"name": "testosterone propionate",
"type": "Metabolite",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
2858
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4834,
"name": "tetrabenazine",
"type": "Synthetic organic",
"abbreviation": "TBZ",
"inn": "tetrabenazine",
"approvalSource": "FDA (2008)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10927,
"name": "tetracycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tetracycline",
"approvalSource": "FDA (1953), UK (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
12760
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11859,
"name": "tetrandrine",
"type": "Natural product",
"abbreviation": "",
"inn": "tetrandrine",
"approvalSource": "China",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10199,
"name": "tezacaftor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tezacaftor",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8933,
"name": "tezepelumab",
"type": "Antibody",
"abbreviation": "",
"inn": "tezepelumab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7327,
"name": "thalidomide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "thalidomide",
"approvalSource": "FDA (1998), EMA (2008)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 413,
"name": "theophylline",
"type": "Natural product",
"abbreviation": "",
"inn": "aminophylline,choline theophyllinate,guaifylline",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7304,
"name": "thiabendazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tiabendazole",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7305,
"name": "thiamylal",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7306,
"name": "thiethylperazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "thiethylperazine",
"approvalSource": "FDA (1961)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6845,
"name": "thioguanine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tioguanine",
"approvalSource": "FDA (1966)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2579,
"name": "thiopental",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "thiopental sodium",
"approvalSource": "FDA (approval date not specified)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 100,
"name": "thioridazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "thioridazine",
"approvalSource": "FDA (1962)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7622,
"name": "thiotepa",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "thiotepa",
"approvalSource": "FDA (1959), EMA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 212,
"name": "thiothixene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tiotixene",
"approvalSource": "FDA (1967)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4818,
"name": "tiagabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tiagabine",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7558,
"name": "tianeptine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tianeptine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9711,
"name": "tibolone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tibolone",
"approvalSource": "EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12881,
"name": "tibremciclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1765,
"name": "ticagrelor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ticagrelor",
"approvalSource": "EMA (2010), FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10928,
"name": "ticarcillin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ticarcillin",
"approvalSource": "FDA (1985)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7307,
"name": "ticlopidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ticlopidine",
"approvalSource": "FDA (1991)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10929,
"name": "tigecycline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tigecycline",
"approvalSource": "FDA (2005), EMA & UK (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8093,
"name": "tildrakizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "tildrakizumab",
"approvalSource": "EMA & FDA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7604,
"name": "tiludronic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tiludronic acid",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 565,
"name": "timolol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "timolol",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12341,
"name": "tinidazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tinidazole",
"approvalSource": "FDA (2004)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6846,
"name": "tinzaparin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tinzaparin sodium",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13859,
"name": "tioconazole",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 367,
"name": "tiotropium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tiotropium bromide",
"approvalSource": "FDA (2004)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8696,
"name": "tipiracil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tipiracil",
"approvalSource": "Japan only",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12685,
"name": "tipranavir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tipranavir",
"approvalSource": "FDA & EMA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9265,
"name": "tirabrutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tirabrutinib",
"approvalSource": "Japan (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2637,
"name": "tiratricol",
"type": "Metabolite",
"abbreviation": "",
"inn": "tiratricol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7957,
"name": "tirbanibulin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tirbanibulin",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6586,
"name": "tirofiban",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tirofiban",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11429,
"name": "tirzepatide",
"type": "Peptide",
"abbreviation": "",
"inn": "tirzepatide",
"approvalSource": "EMA & FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 9592,
"name": "tislelizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "tislelizumab",
"approvalSource": "China (2019), EMA (2023), FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11719,
"name": "tisotumab vedotin",
"type": "Antibody",
"abbreviation": "",
"inn": "tisotumab vedotin",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6058,
"name": "tivozanib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tivozanib",
"approvalSource": "EMA (2017), FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11330,
"name": "tixagevimab",
"type": "Antibody",
"abbreviation": "",
"inn": "tixagevimab",
"approvalSource": "EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7308,
"name": "tizanidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tizanidine",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10930,
"name": "tobramycin",
"type": "Natural product",
"abbreviation": "",
"inn": "tobramycin",
"approvalSource": "FDA (1975), EMA (2011)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7309,
"name": "tocainide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tocainide",
"approvalSource": "FDA (1984)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6881,
"name": "tocilizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "tocilizumab",
"approvalSource": "Japan (2005), EMA (2009), FDA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5677,
"name": "tofacitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tofacitinib",
"approvalSource": "FDA (2012), EMA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13536,
"name": "tofersen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "tofersen",
"approvalSource": "FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9395,
"name": "tofogliflozin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tofogliflozin",
"approvalSource": "Japan (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6847,
"name": "tolazamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolazamide",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7310,
"name": "tolazoline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolazoline",
"approvalSource": "FDA (1948)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6848,
"name": "tolbutamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolbutamide",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6646,
"name": "tolcapone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolcapone",
"approvalSource": "EMA (1997), FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10625,
"name": "tolebrutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolebrutinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8769,
"name": "tolfenamic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolfenamic acid",
"approvalSource": "UK (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7311,
"name": "tolmetin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolmetin",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7404,
"name": "tolrestat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolrestat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 360,
"name": "tolterodine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolterodine",
"approvalSource": "FDA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12766,
"name": "toludesvenlafaxine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "toludesvenlafaxine",
"approvalSource": "China (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2226,
"name": "tolvaptan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tolvaptan",
"approvalSource": "FDA and EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6849,
"name": "topiramate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "topiramate",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7101,
"name": "topotecan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "topotecan",
"approvalSource": "EMA and FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4325,
"name": "toremifene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "toremifene",
"approvalSource": "EMA (1996), FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12989,
"name": "toripalimab",
"type": "Antibody",
"abbreviation": "",
"inn": "toripalimab",
"approvalSource": "FDA (2023), EMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7312,
"name": "torsemide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "torasemide",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6781,
"name": "tositumomab",
"type": "Antibody",
"abbreviation": "",
"inn": "tositumomab",
"approvalSource": "FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12878,
"name": "tosufloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tosufloxacin",
"approvalSource": "Japan",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9977,
"name": "tovorafenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tovorafenib",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2774,
"name": "trabectedin",
"type": "Natural product",
"abbreviation": "",
"inn": "trabectedin",
"approvalSource": "EMA (2007), FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9278,
"name": "tradipitant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tradipitant",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8001,
"name": "tralokinumab",
"type": "Antibody",
"abbreviation": "",
"inn": "tralokinumab",
"approvalSource": "EMA & FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8286,
"name": "tramadol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tramadol",
"approvalSource": "FDA (1995), UK (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6495,
"name": "trametinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trametinib",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6453,
"name": "trandolapril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trandolapril",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6455
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6455,
"name": "trandolaprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trandolaprilat",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6453
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6573,
"name": "tranexamic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tranexamic acid",
"approvalSource": "FDA (1986)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6326,
"name": "tranilast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tranilast",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5281,
"name": "tranylcypromine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tranylcypromine",
"approvalSource": "FDA (1961)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5082,
"name": "trastuzumab",
"type": "Antibody",
"abbreviation": "",
"inn": "trastuzumab",
"approvalSource": "FDA (1998), EMA (2000)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6928,
"name": "trastuzumab emtansine",
"type": "Antibody",
"abbreviation": "",
"inn": "trastuzumab emtansine",
"approvalSource": "EMA and FDA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7102,
"name": "travoprost",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "travoprost",
"approvalSource": "EMA and FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 213,
"name": "trazodone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trazodone",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8462,
"name": "tremelimumab",
"type": "Antibody",
"abbreviation": "",
"inn": "tremelimumab",
"approvalSource": "FDA (2022), EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8281,
"name": "treosulfan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "treosulfan",
"approvalSource": "UK (1992), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5820,
"name": "treprostinil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "treprostinil",
"approvalSource": "FDA (2002), EMA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2644,
"name": "tretinoin",
"type": "Metabolite",
"abbreviation": "",
"inn": "tretinoin",
"approvalSource": "FDA (1995)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2139,
"name": "TRH",
"type": "Peptide",
"abbreviation": "",
"inn": "protirelin",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human, Mouse, Rat"
},
{
"ligandId": 2870,
"name": "triamcinolone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "triamcinolone",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2867,
"name": "triamcinolone acetonide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4329,
"name": "triamterene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "triamterene",
"approvalSource": "FDA (1964)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7313,
"name": "triazolam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "triazolam",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7314,
"name": "trichlormethiazide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trichlormethiazide",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9962,
"name": "trifarotene",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trifarotene",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 214,
"name": "trifluoperazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trifluoperazine",
"approvalSource": "FDA (1959)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4330,
"name": "triflupromazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "triflupromazine",
"approvalSource": "FDA (1957)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8697,
"name": "trifluridine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trifluridine",
"approvalSource": "Japan, FDA (2015), EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11431,
"name": "triheptanoin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "triheptanoin",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7315,
"name": "trihexyphenidyl",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trihexyphenidyl",
"approvalSource": "FDA (1949)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2634,
"name": "triiodothyronine",
"type": "Metabolite",
"abbreviation": "T3",
"inn": "liothyronine",
"approvalSource": "FDA (1956)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9626,
"name": "trilaciclib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trilaciclib",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6850,
"name": "trilostane",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trilostane",
"approvalSource": "FDA (date of approval not specified)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7316,
"name": "trimethadione",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trimethadione",
"approvalSource": "FDA (1946)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7614,
"name": "trimethobenzamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trimethobenzamide",
"approvalSource": "FDA (1974)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10931,
"name": "trimethoprim",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trimethoprim",
"approvalSource": "FDA (1980)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7613,
"name": "trimetrexate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trimetrexate",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7317,
"name": "trimipramine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trimipramine",
"approvalSource": "FDA (1979)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7318,
"name": "tripelennamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tripelennamine",
"approvalSource": "FDA (1948)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1228,
"name": "triprolidine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "triprolidine",
"approvalSource": "FDA (1982)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 1177,
"name": "triptorelin",
"type": "Peptide",
"abbreviation": "",
"inn": "triptorelin",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 12482,
"name": "trofinetide",
"type": "Peptide",
"abbreviation": "",
"inn": "trofinetide",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 2693,
"name": "troglitazone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "troglitazone",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10209,
"name": "troleandomycin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "troleandomycin",
"approvalSource": "FDA (1969)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7328,
"name": "tromethamine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trometamol",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7319,
"name": "tropicamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tropicamide",
"approvalSource": "FDA (1960)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 260,
"name": "tropisetron",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tropisetron",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7480,
"name": "trospium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trospium chloride",
"approvalSource": "FDA (2004)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13476,
"name": "trovafloxacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "trovafloxacin",
"approvalSource": "FDA (1997), EMA (1998)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3920,
"name": "TSH",
"type": "Peptide",
"abbreviation": "",
"inn": "thyrotropin alfa",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
3734,
3731
],
"species": "Human"
},
{
"ligandId": 2635,
"name": "T4",
"type": "Metabolite",
"abbreviation": "",
"inn": "levothyroxine sodium",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2294,
"name": "tubocurarine",
"type": "Natural product",
"abbreviation": "",
"inn": "tubocurarine chloride",
"approvalSource": "FDA (1945)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9922,
"name": "tucatinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tucatinib",
"approvalSource": "FDA (2020), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8305,
"name": "tucidinostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tucidinostat",
"approvalSource": "China",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11675,
"name": "tunlametinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tunlametinib",
"approvalSource": "China (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12099,
"name": "tunodafil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "tunodafil",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13793,
"name": "tuvonralimab",
"type": "Antibody",
"abbreviation": "",
"inn": "tuvonralimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8920,
"name": "ublituximab",
"type": "Antibody",
"abbreviation": "",
"inn": "ublituximab",
"approvalSource": "FDA (2022), EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10176,
"name": "ubrogepant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ubrogepant",
"approvalSource": "FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11577,
"name": "udenafil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "udenafil",
"approvalSource": "South Korea",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10359,
"name": "ulinastatin",
"type": "Peptide",
"abbreviation": "",
"inn": "ulinastatin",
"approvalSource": "Japan, China",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 7460,
"name": "ulipristal acetate",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ulipristal",
"approvalSource": "EMA (2009), FDA (2010)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8916,
"name": "umbralisib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "umbralisib",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7354,
"name": "umeclidinium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "umeclidinium bromide",
"approvalSource": "FDA (2013), EMA (2014)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11089,
"name": "umifenovir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "umifenovir",
"approvalSource": "Russia, China",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12092,
"name": "unecritinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "unecritinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8282,
"name": "unoprostone isopropyl",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "unoprostone",
"approvalSource": "FDA (2000)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12235,
"name": "upacicalcet",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "upacicalcet",
"approvalSource": "Japan (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9246,
"name": "upadacitinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "upadacitinib",
"approvalSource": "EMA & FDA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7621,
"name": "uramustine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "uramustine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13357,
"name": "urapidil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "urapidil",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7104,
"name": "ursodeoxycholic acid",
"type": "Metabolite",
"abbreviation": "",
"inn": "ursodeoxycholic acid",
"approvalSource": "UK (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6885,
"name": "ustekinumab",
"type": "Antibody",
"abbreviation": "",
"inn": "ustekinumab",
"approvalSource": "FDA (2009), EMA (2009)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10871,
"name": "vaborbactam",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vaborbactam",
"approvalSource": "FDA (2017), EMA (2018)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11831,
"name": "vadadustat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vadadustat",
"approvalSource": "Japan (2020), EMA (2023), FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4824,
"name": "valacyclovir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "valaciclovir",
"approvalSource": "FDA (1995, prior history not available)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8694,
"name": "valbenazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "valbenazine",
"approvalSource": "FDA (2017)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2894,
"name": "valdecoxib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "valdecoxib",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
2895
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12282,
"name": "valemetostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "valemetostat",
"approvalSource": "Japan (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4716,
"name": "valganciclovir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "valganciclovir",
"approvalSource": "FDA (2002, prior history not available)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7009,
"name": "valproic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "valproic acid",
"approvalSource": "FDA (1978)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3937,
"name": "valsartan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "valsartan",
"approvalSource": "FDA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9247,
"name": "vamorolone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vamorolone",
"approvalSource": "FDA & EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10932,
"name": "vancomycin",
"type": "Natural product",
"abbreviation": "",
"inn": "vancomycin",
"approvalSource": "FDA (1964), UK (1990)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5717,
"name": "vandetanib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vandetanib",
"approvalSource": "FDA (2011), EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11570,
"name": "vaniprevir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vaniprevir",
"approvalSource": "Japan 2014",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13694,
"name": "vanzacaftor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vanzacaftor",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2054,
"name": "vapreotide",
"type": "Peptide",
"abbreviation": "",
"inn": "vapreotide",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 7320,
"name": "vardenafil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vardenafil",
"approvalSource": "EMA and FDA (2003)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5459,
"name": "varenicline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "varenicline",
"approvalSource": "FDA and EMA (2006)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2168,
"name": "vasopressin",
"type": "Peptide",
"abbreviation": "AVP",
"inn": "vasopressin injection",
"approvalSource": "FDA (date of approval not specified)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human, Mouse, Rat"
},
{
"ligandId": 11677,
"name": "vebreltinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vebreltinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4002,
"name": "vecuronium",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vecuronium bromide",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7437,
"name": "vedolizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "vedolizumab",
"approvalSource": "FDA and EMA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7464,
"name": "velaglucerase alfa",
"type": "Peptide",
"abbreviation": "",
"inn": "velaglucerase alfa",
"approvalSource": "FDA and EMA (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 11269,
"name": "velpatasvir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "velpatasvir",
"approvalSource": "EMA & FDA (2016)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5893,
"name": "vemurafenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vemurafenib",
"approvalSource": "FDA (2011), EMA (2012)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
8548
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 8318,
"name": "venetoclax",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "venetoclax",
"approvalSource": "FDA and EMA (2016)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7321,
"name": "venlafaxine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "venlafaxine",
"approvalSource": "FDA (1993)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2406,
"name": "verapamil",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "verapamil",
"approvalSource": "FDA (1981)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10010,
"name": "vericiguat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "EMA & FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10100,
"name": "vibegron",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vibegron",
"approvalSource": "FDA (2020), EMMA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4806,
"name": "vidarabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vidarabine",
"approvalSource": "FDA (1976)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4821,
"name": "vigabatrin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vigabatrin",
"approvalSource": "FDA (2009), EMA (2018)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7353,
"name": "vilanterol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vilanterol",
"approvalSource": "FDA (2013)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7427,
"name": "vilazodone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vilazodone",
"approvalSource": "FDA (2011)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6310,
"name": "vildagliptin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vildagliptin",
"approvalSource": "EMA & UK (2007)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11346,
"name": "vilobelimab",
"type": "Antibody",
"abbreviation": "",
"inn": "vilobelimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11502,
"name": "viloxazine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "viloxazine",
"approvalSource": "FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11430,
"name": "viltolarsen",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "viltolarsen",
"approvalSource": "FDA (2020)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11190,
"name": "vimseltinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vimseltinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6851,
"name": "vinblastine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vinblastine",
"approvalSource": "FDA (1965)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6785,
"name": "vincristine",
"type": "Natural product",
"abbreviation": "",
"inn": "vincristine",
"approvalSource": "FDA (1963)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7105,
"name": "vinorelbine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vinorelbine",
"approvalSource": "FDA (1994)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5285,
"name": "vinpocetine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vinpocetine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13252,
"name": "viomycin",
"type": "Natural product",
"abbreviation": "",
"inn": "viomycin",
"approvalSource": "FDA (1953)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6975,
"name": "vismodegib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vismodegib",
"approvalSource": "FDA (2012), EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2747,
"name": "vitamin D3",
"type": "Metabolite",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11388,
"name": "voclosporin",
"type": "Peptide",
"abbreviation": "",
"inn": "voclosporin",
"approvalSource": "FDA (2021), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 8681,
"name": "volanesorsen",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "volanesorsen",
"approvalSource": "EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11549,
"name": "vonoprazan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vonoprazan",
"approvalSource": "Japan (2014), FDA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6755,
"name": "von Willebrand factor",
"type": "Peptide",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (2015)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": "Human"
},
{
"ligandId": 4047,
"name": "vorapaxar",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vorapaxar",
"approvalSource": "FDA (2014)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10663,
"name": "vorasidenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vorasidenib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6852,
"name": "vorinostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vorinostat",
"approvalSource": "FDA (2006)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 14430,
"name": "vornorexant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vornorexant",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7351,
"name": "vortioxetine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "vortioxetine",
"approvalSource": "FDA and EMA (2013)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9068,
"name": "vosoritide",
"type": "Peptide",
"abbreviation": "",
"inn": "vosoritide",
"approvalSource": "EMA & FDA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 10559,
"name": "voxelotor",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "voxelotor",
"approvalSource": "FDA (2019), EMA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9296,
"name": "vunakizumab",
"type": "Antibody",
"abbreviation": "",
"inn": "",
"approvalSource": "China NMPA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13616,
"name": "vutrisiran",
"type": "Nucleic acid",
"abbreviation": "",
"inn": "vutrisiran",
"approvalSource": "EMA, FDA & UK MHRA (2022)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13683,
"name": "VX-993",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6853,
"name": "warfarin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "warfarin",
"approvalSource": "FDA (1954)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 57,
"name": "xanomeline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "xanomeline",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13784,
"name": "xeligekimab",
"type": "Antibody",
"abbreviation": "",
"inn": "xeligekimab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6381,
"name": "ximelagatran",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ximelagatran",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": true,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6382
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7900,
"name": "xipamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "xipamide",
"approvalSource": "UK (2002)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 517,
"name": "xylometazoline",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "xylometazoline",
"approvalSource": "",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 102,
"name": "yohimbine",
"type": "Natural product",
"abbreviation": "",
"inn": "",
"approvalSource": "FDA (no date available)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3322,
"name": "zafirlukast",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zafirlukast",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4828,
"name": "zalcitabine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zalcitabine",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4345,
"name": "zaleplon",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zaleplon",
"approvalSource": "FDA (1999)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12307,
"name": "zanamivir",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zanamivir",
"approvalSource": "FDA (1999), EMA (2019)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13627,
"name": "zanidatamab",
"type": "Antibody",
"abbreviation": "",
"inn": "zanidatamab",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9861,
"name": "zanubrutinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zanubrutinib",
"approvalSource": "FDA (2019), EMA (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13433,
"name": "zastaprazan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zastaprazan",
"approvalSource": "South Korea (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11513,
"name": "zavegepant",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zavegepant",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13649,
"name": "zenocutuzumab",
"type": "Antibody",
"abbreviation": "",
"inn": "zenocutuzumab",
"approvalSource": "FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 13512,
"name": "zeprumetostat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zeprumetostat",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 2536,
"name": "ziconotide",
"type": "Peptide",
"abbreviation": "",
"inn": "ziconotide",
"approvalSource": "FDA (2004), EMA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 4825,
"name": "zidovudine",
"type": "Synthetic organic",
"abbreviation": "AZT",
"inn": "zidovudine",
"approvalSource": "FDA (1987)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11680,
"name": "ziftomenib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ziftomenib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 5297,
"name": "zileuton",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zileuton",
"approvalSource": "FDA (1996)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10404,
"name": "zilucoplan",
"type": "Peptide",
"abbreviation": "",
"inn": "zilucoplan",
"approvalSource": "FDA & EMA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
],
"species": ""
},
{
"ligandId": 12349,
"name": "zimberelimab",
"type": "Antibody",
"abbreviation": "",
"inn": "zimberelimab",
"approvalSource": "China (2021)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": true,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 59,
"name": "ziprasidone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "ziprasidone",
"approvalSource": "FDA (2001)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6462,
"name": "zofenopril",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zofenopril",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
6463
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 6463,
"name": "zofenoprilat",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zofenoprilat",
"approvalSource": "FDA",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
6462
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 9209,
"name": "zolbetuximab",
"type": "Antibody",
"abbreviation": "",
"inn": "zolbetuximab",
"approvalSource": "Japan PMDA, EMA & FDA (2024)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 3177,
"name": "zoledronic acid",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zoledronic acid",
"approvalSource": "FDA and EMA (2001)",
"approved": true,
"whoEssential": true,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10875,
"name": "zoliflodacin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zoliflodacin",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": true,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 60,
"name": "zolmitriptan",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zolmitriptan",
"approvalSource": "FDA (1997)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 4348,
"name": "zolpidem",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zolpidem",
"approvalSource": "FDA (1992)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12387,
"name": "zongertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zongertinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7047,
"name": "zonisamide",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zonisamide",
"approvalSource": "FDA (2000), EMA (2005)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7430,
"name": "zopiclone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zopiclone",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 10456,
"name": "zorifertinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zorifertinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 103,
"name": "zotepine",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zotepine",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 11576,
"name": "zucapsaicin",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zucapsaicin",
"approvalSource": "Canada (2010)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 7559,
"name": "zuclopenthixol",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zuclopenthixol",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12858,
"name": "zuranolone",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zuranolone",
"approvalSource": "FDA (2023)",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
},
{
"ligandId": 12389,
"name": "zurletrectinib",
"type": "Synthetic organic",
"abbreviation": "",
"inn": "zurletrectinib",
"approvalSource": "",
"approved": true,
"whoEssential": false,
"withdrawn": false,
"antibacterial": false,
"immuno": false,
"malaria": false,
"labelled": false,
"radioactive": false,
"activeDrugIds": [
],
"prodrugIds": [
],
"complexIds": [
],
"subunitIds": [
]
}
]