[
    {
        "targetId": 284,
        "transducers": "G<sub>s</sub> family",
        "effectors": "Adenylyl cyclase stimulation",
        "comments": "",
        "secondaryMechanism": false,
        "refs": [
            {
                "referenceId": 4351,
                "pmid": 8463333,
                "type": "Journal",
                "title": "J Biol Chem",
                "year": 1993,
                "volume": "268",
                "issue": "11",
                "pages": "8246-50",
                "articleTitle": "Molecular cloning of a novel melanocortin receptor.",
                "authors": "Gantz I, Konda Y, Tashiro T, Shimoto Y, Miwa H, Munzert G, Watson SJ, DelValle J, Yamada T"
            }
        ]
    },
    {
        "targetId": 284,
        "transducers": "G protein (identity unknown)",
        "effectors": "Other - See Comments",
        "comments": "Melanocortin activation of the MC<sub>3</sub> mobilizes intracellular calcium via an incompletely understood pathway(s).",
        "secondaryMechanism": true,
        "refs": [
            {
                "referenceId": 4313,
                "pmid": 11161002,
                "type": "Journal",
                "title": "Physiol Genomics",
                "year": 2001,
                "volume": "5",
                "issue": "1",
                "pages": "11-9",
                "articleTitle": "Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells.",
                "authors": "Mountjoy KG, Kong PL, Taylor JA, Willard DH, Wilkison WO"
            },
            {
                "referenceId": 4354,
                "pmid": 12906838,
                "type": "Journal",
                "title": "Neuropeptides",
                "year": 2003,
                "volume": "37",
                "issue": "4",
                "pages": "201-10",
                "articleTitle": "Evidence for the interaction of protein kinase C and melanocortin 3-receptor signaling pathways.",
                "authors": "Wachira SJ, Hughes-Darden CA, Taylor CV, Ochillo R, Robinson TJ"
            }
        ]
    }
]