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                "type": "Journal",
                "title": "J Med Chem",
                "year": 2024,
                "volume": "67",
                "issue": "14",
                "pages": "11688-11700",
                "articleTitle": "NN1213 - A Potent, Long-Acting, and Selective Analog of Human Amylin.",
                "authors": "Dahl K, Raun K, Hansen JL, Poulsen C, de la Cour CD, Clausen TR, Hansen AMK, John LM, Plesner A, Sun G <i>et al.</i>"
            }
        ]
    },
    {
        "interactionId": 91147,
        "targetId": 46,
        "targetName": "AMY<sub>3</sub> receptor",
        "ligandAsTargetId": 0,
        "targetSpecies": "Human",
        "primaryTarget": false,
        "targetBindingSite": "",
        "ligandId": 13768,
        "ligandName": "cagrilintide",
        "ligandContext": "",
        "endogenous": false,
        "type": "Agonist",
        "action": "Agonist",
        "actionComment": "",
        "selectivity": "Non-selective",
        "concentrationRange": "",
        "affinity": "9.5",
        "affinityParameter": "pEC50",
        "originalAffinity": "3.5x10<sup>-10</sup>",
        "originalAffinityType": "EC50",
        "originalAffinityRelation": "=",
        "assayDescription": "Receptor activation in a cAMP assay",
        "assayConditions": "",
        "useDependent": false,
        "voltageDependent": false,
        "voltage": "",
        "physiologicalVoltage": false,
        "conciseView": false,
        "refs": [
            {
                "referenceId": 48685,
                "pmid": 34288673,
                "type": "Journal",
                "title": "J Med Chem",
                "year": 2021,
                "volume": "64",
                "issue": "15",
                "pages": "11183-11194",
                "articleTitle": "Development of Cagrilintide, a Long-Acting Amylin Analogue.",
                "authors": "Kruse T, Hansen JL, Dahl K, Sch&#xe4;ffer L, Sensfuss U, Poulsen C, Schlein M, Hansen AMK, Jeppesen CB, Dornonville de la Cour C <i>et al.</i>",
                "pubStatus": "",
                "doi": ""
            }
        ]
    },
    {
        "interactionId": 91148,
        "targetId": 46,
        "targetName": "AMY<sub>3</sub> receptor",
        "ligandAsTargetId": 0,
        "targetSpecies": "Human",
        "primaryTarget": false,
        "targetBindingSite": "",
        "ligandId": 13768,
        "ligandName": "cagrilintide",
        "ligandContext": "",
        "endogenous": false,
        "type": "Agonist",
        "action": "Agonist",
        "actionComment": "",
        "selectivity": "Non-selective",
        "concentrationRange": "",
        "affinity": "9.8",
        "affinityParameter": "pIC50",
        "originalAffinity": "1.7x10<sup>-10</sup>",
        "originalAffinityType": "IC50",
        "originalAffinityRelation": "=",
        "assayDescription": "Determined by displacement of 125I-rat amylin binding to AMY3R in a radioligand binding assay",
        "assayConditions": "",
        "useDependent": false,
        "voltageDependent": false,
        "voltage": "",
        "physiologicalVoltage": false,
        "conciseView": false,
        "refs": [
            {
                "referenceId": 48685,
                "pmid": 34288673,
                "type": "Journal",
                "title": "J Med Chem",
                "year": 2021,
                "volume": "64",
                "issue": "15",
                "pages": "11183-11194",
                "articleTitle": "Development of Cagrilintide, a Long-Acting Amylin Analogue.",
                "authors": "Kruse T, Hansen JL, Dahl K, Sch&#xe4;ffer L, Sensfuss U, Poulsen C, Schlein M, Hansen AMK, Jeppesen CB, Dornonville de la Cour C <i>et al.</i>",
                "pubStatus": "",
                "doi": ""
            }
        ]
    }
]