G protein-coupled receptors (GPCRs)

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  • Browse GPCR families and access overviews, key references and selective ligands
  • Follow the links for longer introductions and for detailed annotation on pharmacology, function, structure, physiology and clinical relevance of each receptor
  • View the list of GPCR families go icon to follow link

Ion channels

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Including:

  • Ligand-gated ion channels (LGICs)
  • Voltage-gated ion channels (VGICs)
  • Other ion channels
  • Browse ion channel families and access overviews, key references and selective ligands
  • Follow the links for longer introductions and for detailed annotation on pharmacology, function, structure, physiology and clinical relevance of each channel or subunit
  • View the list of ion channel families go icon to follow link

Nuclear hormone receptors (NHRs)

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  • Browse NHR families and access overviews, key references and selective ligands
  • Follow the links for detailed annotation on pharmacology, function, structure, physiology and clinical relevance of each receptor
  • View the list of NHR families go icon to follow link

Kinases

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  • Browse kinase subfamilies and access large-scale inhibitor screening data.
  • Access detailed clinical information for approved drug kinase inhibitors.
  • View the list of kinase families go icon to follow link

Catalytic receptors

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Transporters

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Enzymes

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  • Browse a subset of enzymes with pharmacological relevance and access overviews, key references and selective ligands
  • Additional data are provided for protein kinases
  • View the list of enzyme families go icon to follow link

Other protein targets

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Immuno-relevant targets

IUPHAR Guide to Immunopharmacology

A Wellcome Trust-funded extension to GtoPdb, aiming to improve data exchange between immunology and pharmacology.

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The Concise Guide to PHARMACOLOGY 2017/18

Concise Guide to Pharmacology 2017/18

A FREE publication snapshot created from the database summary pages.

Access the table of contents go icon to follow link