Chronic granulomatous disease

Disease ID:1223
Name:Chronic granulomatous disease
Associated with:0 target
1 immuno-relevant ligand
Synonyms
Bridges-Good syndrome | CGD | Congenital dysphagocytosis | Quie syndrome
Description
A diverse group of potentially life-threatening hereditary diseases caused by phagocyte bactericidal dysfunction resulting in an inability to resist repeated infectious diseases and a tendency to develop chronic inflammation and widely distributed granulomas. Cross-references to several OMIM IDs.
Database Links
Disease Ontology: DOID:3265
Orphanet: ORPHA379

Targets

No target related data available for Chronic granulomatous disease

Ligands

Key to terms and symbols Click ligand name to view ligand summary Click column headers to sort
Ligand References Clinical and Disease comments
IFN-γ
Immuno Disease Comments: Approved therapy for chronic granulomatous disease.
Clinical Use: Recombinant IFNγ is approved to reduce the frequency of serious infection in chronic granulomatous disease (CGD) and severe malignant osteopetrosis . | View clinical data