Visit the GRAC database for a succinct overview of the properties, selective ligands and key references for:

Visit the IUPHAR database for detailed, peer-reviewed descriptions of the properties, endogenous and synthetic ligands and clinical relevance of:

Browse and search for ligands in both databases:

Search for targets and ligands by name, keyword, identifier, literature reference or chemical structure:

Start using the Guide to Pharmacology:

New database version released 1st Apr 2013. Highlights include:

• Updates to several IUPHAR-DB GPCR and LGIC families;
• Protein kinases added to IUPHAR-DB - first version contains genomic and structural information plus DiscoveRx KINOMEscan^® screening assay of 72 inhibitors. More data coming soon.

Latest news from NC-IUPHAR and BPS:

• Hot topics in pharmacology
• Recent receptor-ligand pairings
• NC-IUPHAR newsletter