Stroke, ischemic

Disease ID:892
Name:Stroke, ischemic
Associated with:4 targets
Synonyms
Cerebral infarction | Cerebrovascular accident
Database Links
Disease Ontology: DOID:3455
OMIM: 601367

Targets

CELSR1
References:  1,3
protein kinase C eta
Comments:  A non-synonymous SNP in PRKCH causes susceptibility to cerebral infarction.
References:  2
Mutations:  protein kinase C eta is associated with 1 mutation. Click here for details
coagulation factor II, thrombin
coagulation factor V

Ligands

No ligand related data available for Stroke, ischemic

References

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1. Gouveia LO, Sobral J, Vicente AM, Ferro JM, Oliveira SA. (2011) Replication of the CELSR1 association with ischemic stroke in a Portuguese case-control cohort. Atherosclerosis, 217 (1): 260-2. [PMID:21511255]

2. Kubo M, Hata J, Ninomiya T, Matsuda K, Yonemoto K, Nakano T, Matsushita T, Yamazaki K, Ohnishi Y, Saito S et al.. (2007) A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction. Nat. Genet., 39 (2): 212-7. [PMID:17206144]

3. Yamada Y, Fuku N, Tanaka M, Aoyagi Y, Sawabe M, Metoki N, Yoshida H, Satoh K, Kato K, Watanabe S, Nozawa Y, Hasegawa A, Kojima T. (2009) Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study. Atherosclerosis, 207 (1): 144-9. [PMID:19403135]