Histamine receptors

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [16,40]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [16].


H1 receptor Show summary » More detailed page

H2 receptor Show summary » More detailed page

H3 receptor Show summary » More detailed page

H4 receptor Show summary » More detailed page


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Further reading

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation:

Paul Chazot, Stephen J. Hill, Hiroyuki Fukui, C. Robin Ganellin, Helmut L. Haas, Roberto Levi, Walter Schunack, Jean-Charles Schwartz, Nigel P. Shankley, Henk Timmerman, J. Michael Young, Rebecca Hills. Histamine receptors. Accessed on 01/12/2015. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=33.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA and Harmar AJ, CGTP Collaborators. (2013) The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors. Br J Pharmacol. 170: 1459–1581.