Complement peptide receptors

Formerly known as: Anaphylatoxin receptors

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Complement peptide receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Complement peptide receptors [19]) are activated by the endogenous ~75 amino-acid anaphylatoxin polypeptides C3a (C3, P01024). C4a (C4A, P0C0L4) and C5a (C5, P01031), generated upon stimulation of the complement cascade.


C3a receptor Show summary » More detailed page

C5a1 receptor Show summary » More detailed page

C5a2 receptor Show summary » More detailed page


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Further reading

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation:

Peter Monk, Trent Woodruff, Liam Coulthard, Owen Hawksworth, Vincenzo Mitolo, Maria Panaro. Complement peptide receptors. Accessed on 29/11/2015. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA and Harmar AJ, CGTP Collaborators. (2013) The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors. Br J Pharmacol. 170: 1459–1581.