Complement peptide receptors

Formerly known as: Anaphylatoxin receptors

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Complement peptide receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Complement peptide receptors [19]) are activated by the endogenous ~75 amino-acid anaphylatoxin polypeptides C3a (C3, P01024). C4a (C4A, P0C0L4) and C5a (C5, P01031), generated upon stimulation of the complement cascade.


C3a receptor Show summary » More detailed page

C5a1 receptor Show summary » More detailed page

C5a2 receptor Show summary » More detailed page


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Further reading

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation:

Peter Monk, Trent Woodruff, Liam Coulthard, Owen Hawksworth, Vincenzo Mitolo, Maria Panaro. Complement peptide receptors. Accessed on 25/10/2016. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Davenport AP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors. Br J Pharmacol. 172: 5744-5869.