2A. Hepatocyte nuclear factor-4 receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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The nomenclature of hepatocyte nuclear factor-4 receptors is agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [1]. While linoleic acid has been identified as the endogenous ligand for HNF4α its function remains ambiguous [4]. HNF4γ has yet to be paired with an endogenous ligand.

Receptors

Hepatocyte nuclear factor-4-α / NR2A1 C Show summary » More detailed page

Hepatocyte nuclear factor-4-γ / NR2A2 C Show summary » More detailed page

Further reading

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References

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation:

Frances M. Sladek. 2A. Hepatocyte nuclear factor-4 receptors. Accessed on 14/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=91.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Cidlowski JA, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Nuclear hormone receptors. Br J Pharmacol. 174 Suppl 1: S208-S224.