XY101 [Ligand Id: 10366] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| RAR-related orphan receptor-γ in Human [GtoPdb: 600] [UniProtKB: P51449] | ||||||||
| GtoPdb | In vitro binding to the RORγ LBD measured using AlphaScreen technology. | - | 6.12 | pKd | 750 | nM | Kd | J Med Chem (2019) 62: 4716-4730 [PMID:30964293] |
| GtoPdb | In vitro binding to the RORγ LBD measured in a isothermal titration calorimetry (ITC) assay. | - | 6.42 | pKd | 380 | nM | Kd | J Med Chem (2019) 62: 4716-4730 [PMID:30964293] |
| GtoPdb | Measuring disruprion of RORγ-driven transcriptional activity in a Gal4 reporter assay in 293 T cells. | - | 7.52 | pIC50 | 30 | nM | IC50 | J Med Chem (2019) 62: 4716-4730 [PMID:30964293] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
