tobramycin [Ligand Id: 10930] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1747 (47663, Aktob, Bethkis, Bramitob, Kitabis pak, Nebcin, Nebicin, Nebramycin, Nebramycin factor 6, Nebramycin vi, Nebris, NSC-180514, Obramycin, Tobi, Tobi podhaler, Tobradex, Tobradex St, Tobralex, Tobramycin, Tobravisc, Tobrex, Tymbrineb, Vantobra)
  • Human immunodeficiency virus type 1 REV in Human immunodeficiency virus 1 [ChEMBL: CHEMBL3852] [UniProtKB: Q77YF8]
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  • TAS2R20 in Human [GtoPdb: 671] [UniProtKB: P59543]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Human immunodeficiency virus type 1 REV in Human immunodeficiency virus 1 (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3852] [UniProtKB: Q77YF8]
ChEMBL Tested for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropy F 5.39 pKd 4110 nM Kd Bioorg Med Chem Lett (2001) 11: 1127-1131 [PMID:11354359]
TAS2R20 in Human [GtoPdb: 671] [UniProtKB: P59543]
GtoPdb - - 4.29 pEC50 50970 nM EC50 FASEB J (2019) 33: 501-517 [PMID:30011231]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]