NTQ1062 [Ligand Id: 12112] activity data from GtoPdb

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  • AKT serine/threonine kinase 1 in Human [GtoPdb: 1479] [UniProtKB: P31749]
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  • AKT serine/threonine kinase 2 in Human [GtoPdb: 1480] [UniProtKB: P31751]
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  • AKT serine/threonine kinase 3 in Human [GtoPdb: 2286] [UniProtKB: Q9Y243]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
AKT serine/threonine kinase 1 in Human [GtoPdb: 1479] [UniProtKB: P31749]
GtoPdb - - 9.4 pIC50 0.4 nM IC50 J Med Chem (2022) 65: 8144-8168 [PMID:35679512]
AKT serine/threonine kinase 2 in Human [GtoPdb: 1480] [UniProtKB: P31751]
GtoPdb - - 8.2 pIC50 6.3 nM IC50 J Med Chem (2022) 65: 8144-8168 [PMID:35679512]
AKT serine/threonine kinase 3 in Human [GtoPdb: 2286] [UniProtKB: Q9Y243]
GtoPdb - - 10 pIC50 0.1 nM IC50 J Med Chem (2022) 65: 8144-8168 [PMID:35679512]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.