VU0486846 [Ligand Id: 12305] activity data from GtoPdb

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  • M1 receptor in Human [GtoPdb: 13] [UniProtKB: P11229]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
M1 receptor in Human [GtoPdb: 13] [UniProtKB: P11229]
GtoPdb Agonist potency - 5.4 pEC50 4000 nM EC50 ACS Chem Neurosci (2018) 9: 2274-2285 [PMID:29701957]
GtoPdb PAM potency - 6.51 pEC50 310 nM EC50 ACS Chem Neurosci (2018) 9: 2274-2285 [PMID:29701957]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.