compound 25c [PMID: 36649216] [Ligand Id: 12334] activity data from GtoPdb

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  • mitogen-activated protein kinase 8 in Human [GtoPdb: 1496] [UniProtKB: P45983]
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  • mitogen-activated protein kinase 9 in Human [GtoPdb: 1497] [UniProtKB: P45984]
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  • mitogen-activated protein kinase 10 in Human [GtoPdb: 1498] [UniProtKB: P53779]
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  • fms related receptor tyrosine kinase 4 in Human [GtoPdb: 1814] [UniProtKB: P35916]
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  • TRAF2 and NCK interacting kinase in Human [GtoPdb: 2244] [UniProtKB: Q9UKE5]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
mitogen-activated protein kinase 8 in Human [GtoPdb: 1496] [UniProtKB: P45983]
GtoPdb - - 5 pIC50 >10000 nM IC50 J Med Chem (2023) 66: 1273-1300 [PMID:36649216]
mitogen-activated protein kinase 9 in Human [GtoPdb: 1497] [UniProtKB: P45984]
GtoPdb - - 5.03 pIC50 9270 nM IC50 J Med Chem (2023) 66: 1273-1300 [PMID:36649216]
mitogen-activated protein kinase 10 in Human [GtoPdb: 1498] [UniProtKB: P53779]
GtoPdb - - 7.07 pIC50 85.2 nM IC50 J Med Chem (2023) 66: 1273-1300 [PMID:36649216]
fms related receptor tyrosine kinase 4 in Human [GtoPdb: 1814] [UniProtKB: P35916]
GtoPdb - - 6.37 pIC50 423 nM IC50 J Med Chem (2023) 66: 1273-1300 [PMID:36649216]
TRAF2 and NCK interacting kinase in Human [GtoPdb: 2244] [UniProtKB: Q9UKE5]
GtoPdb - - 6.44 pIC50 367 nM IC50 J Med Chem (2023) 66: 1273-1300 [PMID:36649216]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.