denatonium [Ligand Id: 12433] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1738972 (Denatonium)
  • TAS2R10 in Human [GtoPdb: 666] [UniProtKB: Q9NYW0]
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  • TAS2R30 in Human [GtoPdb: 673] [UniProtKB: P59541]
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  • TAS2R46 in Human [GtoPdb: 679] [UniProtKB: P59540]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TAS2R10 in Human [GtoPdb: 666] [UniProtKB: Q9NYW0]
GtoPdb - - 4.13 pEC50 73500 nM EC50 J Neurosci (2013) 33: 201-13 [PMID:23283334]
TAS2R30 in Human [GtoPdb: 673] [UniProtKB: P59541]
GtoPdb - - 6.57 pEC50 270 nM EC50 Chem Senses (2010) 35: 157-70 [PMID:20022913]
TAS2R46 in Human [GtoPdb: 679] [UniProtKB: P59540]
GtoPdb - - 3.62 pEC50 240000 nM EC50 Chem Senses (2010) 35: 157-70 [PMID:20022913]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]