ChEMBL ligand: CHEMBL4752759
epoxide hydrolase 2/Epoxide hydratase in Human [ChEMBL: CHEMBL2409] [GtoPdb: 2970] [UniProtKB: P34913] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
epoxide hydrolase 2/Epoxide hydratase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2409] [GtoPdb: 2970] [UniProtKB: P34913]
GtoPdb	-	-	10.3	pKi	<0.05	nM	Ki	J Med Chem (2021) 64: 1856-1872 [PMID:33550801]
ChEMBL	Inhibition of recombinant human sEH expressed in baculovirus expression system assessed as reduction in ACPU binding incubated for 1 hr by FRET displacement assay	B	10.3	pKi	<0.05	nM	Ki	Bioorg Med Chem (2020) 28: 115735-115735 [PMID:33007552]
ChEMBL	Binding affinity to purified recombinant human sEH by FRET-displacement assay	B	10.3	pKi	<0.05	nM	Ki	J Med Chem (2021) 64: 1856-1872 [PMID:33550801]
ChEMBL	Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assay	B	9.4	pIC50	0.4	nM	IC50	J Med Chem (2021) 64: 5429-5446 [PMID:33945278]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]