tibremciclib [Ligand Id: 12881] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • cyclin dependent kinase 4 in Human [GtoPdb: 1976] [UniProtKB: P11802]
There should be some charts here, you may need to enable JavaScript!
  • cyclin dependent kinase 6 in Human [GtoPdb: 1978] [UniProtKB: Q00534]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cyclin dependent kinase 4 in Human [GtoPdb: 1976] [UniProtKB: P11802]
GtoPdb - - 8.72 pIC50 1.9 nM IC50 US20210261546A1. Crystal form of compound for inhibiting the activity of cdk4/6 and use thereof (2021)
cyclin dependent kinase 6 in Human [GtoPdb: 1978] [UniProtKB: Q00534]
GtoPdb - - 7.66 pIC50 22 nM IC50 US20210261546A1. Crystal form of compound for inhibiting the activity of cdk4/6 and use thereof (2021)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.