LY3522348 [Ligand Id: 13033] activity data from GtoPdb

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  • ketohexokinase in Human [GtoPdb: 3236] [UniProtKB: P50053]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ketohexokinase in Human [GtoPdb: 3236] [UniProtKB: P50053]
GtoPdb Inhibition of fructose conversion to F1P by KHK in HepG2 liver cells - 7.39 pIC50 41 nM IC50 J Med Chem (2023) 66: 15960-15976 [PMID:37992274]
GtoPdb Biochemical inhibition of hKHK-C and hKHK-A isoforms - 7.7 pIC50 20 nM IC50 J Med Chem (2023) 66: 15960-15976 [PMID:37992274]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.