3-iodothyronamine [Ligand Id: 2145] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL201002 (3'-Iodothyronamine) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| TA1 receptor/Trace amine-associated receptor 1 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4908] [GtoPdb: 364] [UniProtKB: Q923Y8] | ||||||||
| ChEMBL | Activity at mouse TAAR1 by measuring cAMP accumulation in HEK293 cells | F | 6 | pEC50 | >1000 | nM | EC50 | J Med Chem (2006) 49: 1101-1112 [PMID:16451074] |
| GtoPdb | - | - | 7 | pEC50 | - | - | - |
Nat Med (2004) 10: 638-42 [PMID:15146179]; J Med Chem (2006) 49: 1101-12 [PMID:16451074]; J Med Chem (2007) 50: 2787-98 [PMID:17497842] |
| TA1 receptor/Trace amine-associated receptor 1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3833] [GtoPdb: 364] [UniProtKB: Q923Y9] | ||||||||
| ChEMBL | Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells | F | 6.1 | pEC50 | 800 | nM | EC50 | J Med Chem (2006) 49: 1101-1112 [PMID:16451074] |
| GtoPdb | - | - | 7.9 | pEC50 | - | - | - |
Nat Med (2004) 10: 638-42 [PMID:15146179]; J Med Chem (2006) 49: 1101-12 [PMID:16451074]; J Med Chem (2007) 50: 2787-98 [PMID:17497842] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
