palmoxiric acid [Ligand Id: 2683] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL12394 (MCN-3802, Palmoxiric acid) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| Carnitine palmitoyltransferase 1A in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2981] [UniProtKB: Q9MYX2] | ||||||||
| ChEMBL | Compound was tested for its inhibitory activity against carnitine palmitoyl transferase-A (CPT-A) | B | 6.05 | pIC50 | 900 | nM | IC50 | J Med Chem (1986) 29: 2184-2190 [PMID:3783579] |
| Carnitine palmitoyltransferase 1A in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3858] [UniProtKB: P32198] | ||||||||
| ChEMBL | Inhibition of carnitine palmitoyl transferase (CPT), assessed with isolated rat liver mitochondria | B | 7.4 | pIC50 | 40 | nM | IC50 | J Med Chem (1987) 30: 1094-1097 [PMID:3585906] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
