2MD [Ligand Id: 2776] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL605525 (2MD, Dp001) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Vitamin D receptor in Human [GtoPdb: 605] [UniProtKB: P11473] | ||||||||
| GtoPdb | - | - | 10 | pEC50 | - | - | - | J Med Chem (1998) 41: 4662-74 [PMID:9804706] |
| Vitamin D receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3150] [GtoPdb: 605] [UniProtKB: P13053] | ||||||||
| ChEMBL | Displacement of [3H]1alpha,25-(OH)2D3 from rat recombinant full length VDR | B | 10 | pKi | 0.1 | nM | Ki | J Med Chem (2010) 53: 8642-8649 [PMID:21105677] |
| ChEMBL | Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR after overnight incubation by scintillation counting | B | 10 | pKi | 0.1 | nM | Ki | J Med Chem (2012) 55: 4352-4366 [PMID:22490010] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
