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ChEMBL ligand: CHEMBL259067 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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RAR-related orphan receptor-α/Nuclear receptor ROR-alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5868] [GtoPdb: 598] [UniProtKB: P35398] | ||||||||
ChEMBL | Inhibition of GAL4-tagged RORalpha by luciferase assay | B | 4.48 | pIC50 | >33000 | nM | IC50 | Bioorg Med Chem Lett (2008) 18: 2628-2632 [PMID:18374567] |
Steroidogenic factor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4666] [GtoPdb: 632] [UniProtKB: Q13285] | ||||||||
ChEMBL | Inhibition of GAL4-tagged NR5A1 by luciferase assay | B | 6.12 | pIC50 | 760 | nM | IC50 | Bioorg Med Chem Lett (2008) 18: 2628-2632 [PMID:18374567] |
ChEMBL | Inhibition of Gal4-fused human SF1 LBD (198 to 462 residues) expressed in CHO-K1 cells | B | 7.52 | pIC50 | 30 | nM | IC50 | ACS Med Chem Lett (2020) 11: 365-370 [PMID:32184971] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]