N-homo-γ-linolenoylethanolamine [Ligand Id: 5444] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL121229 (Dihomo-Gamma-Linolenoyl Ethanolamide) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CB1 receptor/Cannabinoid CB1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554] | ||||||||
| ChEMBL | Binding affinity against the cannabinoid receptor | B | 6.22 | pKi | 598 | nM | Ki | J Med Chem (1997) 40: 659-667 [PMID:9057852] |
| ChEMBL | Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor] | B | 7.27 | pKi | 53.4 | nM | Ki | J Med Chem (2002) 45: 3649-3659 [PMID:12166938] |
| CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272] | ||||||||
| ChEMBL | In vitro binding affinity was determined against rat brain Cannabinoid receptor 1 | B | 7.27 | pKi | 53.4 | nM | Ki | J Med Chem (1997) 40: 659-667 [PMID:9057852] |
| ChEMBL | Binding affinity for cannabinoid receptor 1 | B | 7.28 | pKi | 53 | nM | Ki | J Med Chem (2005) 48: 5059-5087 [PMID:16078824] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
