Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL13883 (4-hydroxy-3-methoxy-benzyldehyde, FEMA NO. 3107, H-0264, Lioxin, Methylprotocatechuic aldehyde, NPLC-0145, NSC-15351, NSC-403658, NSC-48383, P-hydroxy-m-methoxybenzaldehyde, Rhovanil, Vanillic aldehyde, Vanillin, vanilline, Vanillin melting point standard, Vanillin, natural) |
---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
tripartite motif containing 33/E3 ubiquitin-protein ligase TRIM33 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2176772] [GtoPdb: 2254] [UniProtKB: Q9UPN9] | ||||||||
ChEMBL | Inhibition of recombinant TRIM33 PHD bromodomain (unknown origin) using biotinylated H3 peptide (H3K9me3K18ac) by AlphaScreen assay | B | 6.49 | pIC50 | 325.6 | nM | IC50 | WO-2018200988-A1. Inhibitors of trim33 and methods of use (null) |
4-aminobutyrate aminotransferase/Gamma-amino-N-butyrate transaminase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2044] [GtoPdb: 2464] [UniProtKB: P80404] | ||||||||
ChEMBL | Inhibitory activity against GABAT | B | 4.77 | pIC50 | 17100 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 592-595 [PMID:16290145] |
Pancreatic triacylglycerol lipase in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1687677] [UniProtKB: P00591] | ||||||||
ChEMBL | Inhibition of pig pancreatic lipase assessed as p-NPB hydrolysis by ELISA | B | 4.13 | pIC50 | 74400 | nM | IC50 | Bioorg Med Chem Lett (2011) 21: 1512-1514 [PMID:21282056] |
aldehyde dehydrogenase 5 family member A1/Succinate semialdehyde dehydrogenase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1911] [GtoPdb: 2466] [UniProtKB: P51649] | ||||||||
ChEMBL | Inhibitory activity against SSADH | B | 4.81 | pIC50 | 15600 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 592-595 [PMID:16290145] |
tripartite motif containing 24/Transcription intermediary factor 1-alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3108638] [GtoPdb: 2252] [UniProtKB: O15164] | ||||||||
ChEMBL | Inhibition of recombinant TRIM24 (unknown origin) using biotinylated H3 peptide (H3K9me3K18ac) by AlphaScreen assay | B | 6.79 | pIC50 | 162 | nM | IC50 | WO-2018200988-A1. Inhibitors of trim33 and methods of use (null) |
TAS2R14 in Human [GtoPdb: 668] [UniProtKB: Q9NYV8] | ||||||||
GtoPdb | - | - | 3.24 | pEC50 | 570000 | nM | EC50 | Front Nutr (2021) 8: 683627 [PMID:34307435] |
TAS2R20 in Human [GtoPdb: 671] [UniProtKB: P59543] | ||||||||
GtoPdb | - | - | 3.28 | pEC50 | 530000 | nM | EC50 | Front Nutr (2021) 8: 683627 [PMID:34307435] |
TAS2R39 in Human [GtoPdb: 675] [UniProtKB: P59534] | ||||||||
GtoPdb | - | - | 3.06 | pEC50 | 870000 | nM | EC50 | Front Nutr (2021) 8: 683627 [PMID:34307435] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]