Z-Arg-Leu-Val-Agly-Ile-Val-OMe [Ligand Id: 6534] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2028907 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| cathepsin B/Cathepsin B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4072] [GtoPdb: 2343] [UniProtKB: P07858] | ||||||||
| ChEMBL | Inhibition of Human Cathepsin B | B | 10.06 | pKi | 0.09 | nM | Ki | J Med Chem (2002) 45: 4202-4211 [PMID:12213061] |
| GtoPdb | - | - | 10.1 | pKi | 0.09 | nM | Ki | J Med Chem (2002) 45: 4202-11 [PMID:12213061] |
| cathepsin K/Cathepsin K in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL268] [GtoPdb: 2350] [UniProtKB: P43235] | ||||||||
| ChEMBL | Inhibition of Human Cathepsin K | B | 7.68 | pKi | 21 | nM | Ki | J Med Chem (2002) 45: 4202-4211 [PMID:12213061] |
| Papain in Carica papaya (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4779] [UniProtKB: P00784] | ||||||||
| ChEMBL | In vitro inhibition of papain. | B | 9.11 | pKi | 0.77 | nM | Ki | J Med Chem (2002) 45: 4202-4211 [PMID:12213061] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
