gosogliptin [Ligand Id: 7413] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL515387 (Gosogliptin, PF-00734200, PF-734,200, PF-734200) |
|---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Beta amyloid A4 protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2487] [UniProtKB: P05067] | ||||||||
| ChEMBL | Inhibition of APP in human leukocytes | B | 4.52 | pIC50 | >30000 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
| Dipeptidyl-peptidase 7/Dipeptidyl peptidase II in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3976] [GtoPdb: 1605] [UniProtKB: Q9UHL4] | ||||||||
| ChEMBL | Inhibition of human recombinant DPP2 | B | 5.48 | pIC50 | 3300 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
| dipeptidyl peptidase 3/Dipeptidyl peptidase III in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4520] [GtoPdb: 2355] [UniProtKB: Q9NY33] | ||||||||
| ChEMBL | Inhibition of DPP3 in human erythrocytes | B | 4.52 | pIC50 | >30000 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
| dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL284] [GtoPdb: 1612] [UniProtKB: P27487] | ||||||||
| ChEMBL | Inhibition of human recombinant DPP4 | B | 7.89 | pIC50 | 12.9 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
| ChEMBL | Inhibition of dipeptidyl peptidase 4 (unknown origin) | B | 7.89 | pIC50 | 12.9 | nM | IC50 | Med Chem Res (2013) 22: 4505-4521 |
| ChEMBL | Inhibition of human plasma DPP4 | B | 7.95 | pIC50 | 11.3 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
| dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4653] [GtoPdb: 1612] [UniProtKB: P14740] | ||||||||
| ChEMBL | Inhibition of rat plasma DPP4 | B | 7.89 | pIC50 | 12.8 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
| dipeptidyl peptidase 9/Dipeptidyl peptidase IX in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4793] [GtoPdb: 2357] [UniProtKB: Q86TI2] | ||||||||
| ChEMBL | Inhibition of human DPP9 | B | 5.22 | pIC50 | 5980 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
| dipeptidyl peptidase 8/Dipeptidyl peptidase VIII in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4657] [GtoPdb: 2356] [UniProtKB: Q6V1X1] | ||||||||
| ChEMBL | Inhibition of human recombinant DPP8 | B | 5.15 | pIC50 | 7000 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
| fibroblast activation protein alpha/Fibroblast activation protein alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4683] [GtoPdb: 2365] [UniProtKB: Q12884] | ||||||||
| ChEMBL | Inhibition of human FAP expressed in african green monkey COS1 cells | B | 4.99 | pIC50 | 10300 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
| prolyl endopeptidase/Prolyl endopeptidase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3202] [GtoPdb: 2395] [UniProtKB: P48147] | ||||||||
| ChEMBL | Inhibition of POP | B | 4.52 | pIC50 | >30000 | nM | IC50 | Bioorg Med Chem Lett (2009) 19: 1991-1995 [PMID:19275964] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
