T140 [Ligand Id: 853] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2370138 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CXCR4/C-X-C chemokine receptor type 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2107] [GtoPdb: 71] [UniProtKB: P61073] | ||||||||
| GtoPdb | - | - | 8.6 | pIC50 | - | - | - |
J Biol Chem (2002) 277: 24515-24521 [PMID:11923301]; Biochem Biophys Res Commun (1998) 253: 877-82 [PMID:9918823] |
| ChEMBL | Inhibition of HIV-induced cytopathogenicity in MT-4 cell | F | 8.48 | pEC50 | 3.3 | nM | EC50 | Bioorg Med Chem Lett (2000) 10: 2633-2637 [PMID:11128640] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
