compound 2 [PMID: 11934595] [Ligand Id: 8562] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL282896
  • bone morphogenetic protein 1/Bone morphogenetic protein 1 in Human [ChEMBL: CHEMBL3898] [GtoPdb: 2333] [UniProtKB: P13497]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
bone morphogenetic protein 1/Bone morphogenetic protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3898] [GtoPdb: 2333] [UniProtKB: P13497]
GtoPdb - - 6.7 pIC50 200 nM IC50 Bioorg Med Chem Lett (2002) 12: 1233-5 [PMID:11934595]
ChEMBL Inhibitory activity against Procollagen C-Proteinase (PCP) B 9.7 pIC50 0.2 nM IC50 Bioorg Med Chem Lett (2002) 12: 1233-1235 [PMID:11934595]
ChEMBL Inhibitory activity against Procollagen C-Proteinase (PCP) B 9.7 pIC50 0.2 nM IC50 Bioorg Med Chem Lett (2002) 12: 1233-1235 [PMID:11934595]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]