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ChEMBL ligand: CHEMBL205904 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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coagulation factor X/Coagulation factor X in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL244] [GtoPdb: 2359] [UniProtKB: P00742] | ||||||||
ChEMBL | Inhibition of F10a | B | 4.94 | pKi | 11400 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 2200-2204 [PMID:16460935] |
complement C1s/Complement C1s in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3913] [GtoPdb: 2335] [UniProtKB: P09871] | ||||||||
GtoPdb | - | - | 8 | pKi | 10 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 2200-4 [PMID:16460935] |
ChEMBL | Inhibition of C1S | B | 8 | pKi | 10 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 2200-2204 [PMID:16460935] |
plasminogen/Plasminogen in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1801] [GtoPdb: 2394] [UniProtKB: P00747] | ||||||||
ChEMBL | Inhibition of plasmin | B | 4.89 | pKi | >13000 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 2200-2204 [PMID:16460935] |
coagulation factor II, thrombin/Thrombin in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL204] [GtoPdb: 2362] [UniProtKB: P00734] | ||||||||
ChEMBL | Inhibition of thrombin | B | 4.82 | pKi | >15000 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 2200-2204 [PMID:16460935] |
plasminogen activator, tissue type/Tissue-type plasminogen activator in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1873] [GtoPdb: 2392] [UniProtKB: P00750] | ||||||||
ChEMBL | Inhibition of tPA | B | 5 | pKi | >10000 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 2200-2204 [PMID:16460935] |
plasminogen activator, urokinase/Urokinase-type plasminogen activator in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3286] [GtoPdb: 2393] [UniProtKB: P00749] | ||||||||
ChEMBL | Inhibition of uPA | B | 5 | pKi | >10000 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 2200-2204 [PMID:16460935] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]