AZ3451 [Ligand Id: 9560] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| PAR2 in Human [GtoPdb: 348] [UniProtKB: P55085] | ||||||||
| GtoPdb | In a BIACORE assay. | - | 7.87 | pKd | 13.5 | nM | Kd | Nature (2017) 545: 112-115 [PMID:28445455] |
| GtoPdb | Antagonism of SLIGRL-NH2-induced IP1 formation. | - | 7.64 | pIC50 | 23 | nM | IC50 | Nature (2017) 545: 112-115 [PMID:28445455] |
| GtoPdb | In a FLIPR calcium accumulation assay, vs. SLIGRL activation. | - | 8.27 | pIC50 | 5.4 | nM | IC50 | Nature (2017) 545: 112-115 [PMID:28445455] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
