Synonyms: SCH 79797 | SCH79797
Compound class:
Synthetic organic
Comment: Potent, selective non-peptide PAR1 antagonist. Marketed as SCH-79797 dihydrochloride.
Other biological activity: SCH-79797 has been reported to exhibit antibacterial activity against Gram-positive and -negative bacteria, including MRSA and other clinically significant bacterial pathogens, with a low frequency of resistance in vivo [2]. The authors show that SCH-79797 targets both bacterial folate metabolism and membrane integrity to mediate its antibacterial effect. Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
N'-cyclopropyl-7-[(4-propan-2-ylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine |
Synonyms |
SCH 79797 | SCH79797 |
Database Links | |
Specialist databases | |
Antibiotic DB | SCH79797 |
GPCRdb Ligand | SCH-79797 |
Other databases | |
ChEBI | CHEBI:94998 |
ChEMBL Ligand | CHEMBL63426 |
GtoPdb PubChem SID | 405560412 |
PubChem CID | 4259181 |
Search Google for chemical match using the InChIKey | AVXQPEKZIGPIJW-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | AVXQPEKZIGPIJW |
UniChem Compound Search for chemical match using the InChIKey | AVXQPEKZIGPIJW-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | AVXQPEKZIGPIJW-UHFFFAOYSA-N |