EG3287   Click here for help

GtoPdb Ligand ID: 11290

Synonyms: VEGFA(138-165)
Compound class: Peptide or derivative
Comment: This peptide corresponds to the exon 7-encoded neuropilin-1-binding site of VEGF165 [1]. It induces tumour cell and endothelial cell apoptosis via binding to neuropilin 1.
The peptide sequence was claimed in Ark Therapeutics' patent WO2003082918A1 that was granted in 2003 [2], in which EG3287 is noted as being a bicyclic form of Ac-SCKNTDSRCKARQLELNERTCRCDKPRR.
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

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Classification Click here for help
Compound class Peptide or derivative
Synonyms Click here for help
VEGFA(138-165)
Database Links Click here for help
GtoPdb PubChem SID 434321725