Synonyms: Triazavirin® | TZV
Compound class:
Synthetic organic
Comment: Riamilovir is a synthetic guanine derivative that acts as a broad-spectrum antiviral agent. It disrupts viral transcription and replication, with antiviral activity against a range of RNA viruses. The exact molecular target has not been reported, although molecular docking studies suggest an interaction of riamilovir with SARS-CoV-2 Mpro (3CL protease) [3]. Consequently, riamilovir has been advanced into clinical evaluation for potential anti-SARS-CoV-2 activity.
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-one |
International Nonproprietary Names | |
INN number | INN |
10616 | riamilovir |
Synonyms |
Triazavirin® | TZV |
Database Links | |
ChEMBL Ligand | CHEMBL1618116 |
DrugBank Ligand | DB15622 |
GtoPdb PubChem SID | 464244137 |
PubChem CID | 3113817 |
Search Google for chemical match using the InChIKey | IDVQGNMSSHPZSJ-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | IDVQGNMSSHPZSJ |
Search PubMed clinical trials | riamilovir |
Search PubMed titles | riamilovir |
Search PubMed titles/abstracts | riamilovir |
UniChem Compound Search for chemical match using the InChIKey | IDVQGNMSSHPZSJ-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | IDVQGNMSSHPZSJ-UHFFFAOYSA-N |