JNJ-10191584

Ligand id: 1277

Name: JNJ-10191584

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 52.23
Molecular weight 278.09
XLogP 0.7
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(6-chloro-1H-benzimidazol-2-yl)-(4-methylpiperazin-1-yl)methanone
Synonyms
compound 12 [1] | JNJ 10191584 | VUF 6002 | VUF6002
Database Links
BindingDB Ligand 50179335
CAS Registry No. 73903-17-0 (source: Scifinder)
ChEMBL Ligand CHEMBL185951
PubChem CID 10446295
Search Google for chemical match using the InChIKey MOIWSUQWIOVGRH-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MOIWSUQWIOVGRH
Search UniChem for chemical match using the InChIKey MOIWSUQWIOVGRH-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone MOIWSUQWIOVGRH
Wikipedia VUF-6002
Comments
JNJ-10191584 is a selective, orally active antagonist of the histamine H4 receptor [1-2].