Synonyms: C-176 STING inhibitor
Compound class:
Synthetic organic
Comment: A covalent inhibitor of mouse stimulator of interferon genes (mSTING) protein, with no effect on the human protein [1]. C-176 binding blocks activation-induced palmitoylation of mSTING and clustering of STING that plays a part in promoting downstream inflammatory signalling.
|
|
Classification | |
Compound class | Synthetic organic |
IUPAC Name |
N-(4-iodophenyl)-5-nitrofuran-2-carboxamide |
Synonyms |
C-176 STING inhibitor |
Database Links | |
CAS Registry No. | 314054-00-7 (source: PubChem) |
ChEMBL Ligand | CHEMBL3593839 |
GtoPdb PubChem SID | 491299918 |
PubChem CID | 1103958 |
Search Google for chemical match using the InChIKey | JBIKQXOZLBLMKI-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | JBIKQXOZLBLMKI |
UniChem Compound Search for chemical match using the InChIKey | JBIKQXOZLBLMKI-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | JBIKQXOZLBLMKI-UHFFFAOYSA-N |