PAF

Ligand id: 1831

Name: PAF

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 26
Topological polar surface area 103.93
Molecular weight 523.36
XLogP 6.51
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
IUPAC Name
[(2R)-2-acetyloxy-3-hexadecoxypropyl] 2-trimethylazaniumylethyl phosphate
Synonyms
PAF (C16) | PAF C-16 | platelet activating factor
Comments
PAF is an endogenous platelet-activating factor; PAF receptor agonist. PAF-PAFR signalling plays a role in a wide range of biological processes including vasodilation, superoxide formation, cell proliferation, angiogenesis and regulation of the inflammatory response.
Database Links
CAS Registry No. 74389-68-7
ChEBI CHEBI:44811
ChEMBL Ligand CHEMBL1235246
DrugBank Ligand DB02261
GtoPdb PubChem SID 135651534
PubChem CID 108156
RCSB PDB Ligand PFS
Search Google for chemical match using the InChIKey HVAUUPRFYPCOCA-AREMUKBSSA-N
Search Google for chemicals with the same backbone HVAUUPRFYPCOCA
Search UniChem for chemical match using the InChIKey HVAUUPRFYPCOCA-AREMUKBSSA-N
Search UniChem for chemicals with the same backbone HVAUUPRFYPCOCA
Wikipedia Platelet-activating_factor

Product suppliers

Tocris
PAF (C16)
Cat. No. 2940