PGF

Ligand id: 1884

Name: PGF

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 12
Topological polar surface area 97.99
Molecular weight 354.24
XLogP 3.2
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
IUPAC Name
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid
International Nonproprietary Names
INN number INN
3074 dinoprost
Synonyms
prostaglandin F
Database Links
CAS Registry No. 551-11-1 (source: Scifinder)
ChEBI CHEBI:15553
ChEMBL Ligand CHEMBL815
GtoPdb PubChem SID 135651540
PubChem CID 5280363
Search Google for chemical match using the InChIKey PXGPLTODNUVGFL-YNNPMVKQSA-N
Search Google for chemicals with the same backbone PXGPLTODNUVGFL
Search PubMed clinical trials dinoprost
Search PubMed titles dinoprost
Search PubMed titles/abstracts dinoprost
Search UniChem for chemical match using the InChIKey PXGPLTODNUVGFL-YNNPMVKQSA-N
Search UniChem for chemicals with the same backbone PXGPLTODNUVGFL
Wikipedia Prostaglandin_F2alpha
Comments
PGF is a naturally-occurring prostanoid which functions as a potent vasoconstrictor. The synthetically produced drug, dinoprost, is chemically identical to the endogenous prostaglandin [3].