substance P

Ligand id: 2098

Name: substance P

Abbreviated name: SP

Species: Human, Mouse, Rat

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Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
IUPAC Name
(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
TAC1 tachykinin precursor 1 Human preprotachykinin 1 (PPT-1) neurokinin 1, neurokinin 2, neurokinin alpha, neuromedin L, neuropeptide gamma, neuropeptide K, NKNA, NPK, substance K, substance P, TAC2, tachykinin, precursor 1, tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
Tac1 tachykinin 1 Mouse preprotachykinin 1 (PPT-1) neurokinin 1, neurokinin A, NK1, NK-1, Nkna, PPTA, PPT-A, preprotachykinin A, SP, substance P
Tac1 tachykinin, precursor 1 Rat preprotachykinin 1 (PPT-1) PPT, Ppt5fl, PPTA3, protachykinin-1, RATPPTA3, TAC, tachykinin, tachykinin 1, tachykinin, precursor 1, Tachykinin (substance P neurokinin A neuropeptide K neuropeptide gamma), Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma)
Database Links
BindingDB Ligand 50001450
CAS Registry No. 33507-63-0
ChEMBL Ligand CHEMBL235363
GtoPdb PubChem SID 135651888
PubChem CID 36511
Search Google for chemical match using the InChIKey ADNPLDHMAVUMIW-CUZNLEPHSA-N
Search Google for chemicals with the same backbone ADNPLDHMAVUMIW
Search UniChem for chemical match using the InChIKey ADNPLDHMAVUMIW-CUZNLEPHSA-N
Search UniChem for chemicals with the same backbone ADNPLDHMAVUMIW
UniProtKB P20366 (Hs), P41539 (Mm), P06767 (Rn)
Wikipedia Substance_p

Product suppliers

Tocris
Substance P
Cat. No. 1156