conivaptan

Ligand id: 2203

Name: conivaptan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 78.09
Molecular weight 498.21
XLogP 9.93
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (2005))
IUPAC Name
N-[4-(2-methyl4,5-dihydro-3H-imidazo[5,4-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamide
International Nonproprietary Names
INN number INN
7947 conivaptan
Synonyms
Vaprisol®
YM-087
YM087
Database Links
BindingDB Ligand 50319771
CAS Registry No. 210101-16-9
ChEMBL Ligand CHEMBL1755
DrugBank Ligand DB00872
PharmGKB Drug PA164742939
PubChem CID 151171
Search Google for chemical match using the InChIKey IKENVDNFQMCRTR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone IKENVDNFQMCRTR
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Wikipedia Conivaptan
Comments
Conivaptan is a non-peptide vasopressin receptor antagonist. It antagonises the V1A and V2 receptors but does not inhibit V1B receptor activity.