anandamide

Ligand id: 2364

Name: anandamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 17
Topological polar surface area 49.33
Molecular weight 347.28
XLogP 7.43
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
IUPAC Name
(5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide
Synonyms
AEA
arachidonoyl ethanolamide
N-arachidonoylethanolamine
Database Links
BindingDB Ligand 22988
CAS Registry No. 94421-68-8 (source: ChEBI)
ChEBI CHEBI:2700
ChEMBL Ligand CHEMBL15848
Human Metabolome Database HMDB04080
PubChem CID 5281969
Search Google for chemical match using the InChIKey LGEQQWMQCRIYKG-DOFZRALJSA-N
Search Google for chemicals with the same backbone LGEQQWMQCRIYKG
Wikipedia Anandamide
Comments
Anandamide is an endogenous cannabinoid neurotransmitter found in animal and human organs, especially in the brain. It activates the cannabinoid receptors CB1 and CB2. Anandamide is also known to be an endogenous activator of the TRPV1 cation channel [2,10], which is involved in regulation of body temperature and nociception.